- Ingenol Mebutate Gel for Actinic Keratosis
[作者：Lebwohl, M; Swanson, N; Anderson, LL; Melgaard, A; Xu, ZY; Berman, B,期刊：New England Journal of Medicine, 页码：1010-1019 , 文章类型： Article，,卷期：2012年366-11]
- BACKGROUND Actinic keratosis is a common precursor to sun-related squamous-cell carcinoma. Treating actinic keratoses and the surrounding skin area (i.e., field therapy) can eradicate clinical and subclinical actinic ker...
- Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
[作者：Comi, G; Jeffery, D; Kappos, L; Montalban, X; Boyko, A; Rocca, MA; Filippi, M,期刊：New England Journal of Medicine, 页码：1000-1009 , 文章类型： Article，,卷期：2012年366-11]
- BACKGROUND Two proof-of-concept clinical trials have provided evidence that laquinimod reduces disease activity in patients with relapsing-remitting multiple sclerosis. METHODS We conducted a randomized, double-blind, ph...
- Closure or Medical Therapy for Cryptogenic Stroke with Patent Foramen Ovale
[作者：Furlan, AJ; Reisman, M; Massaro, J; Mauri, L; Adams, H; Albers, GW; Felberg, R; Herrmann, H; Kar, S; Landzberg, M; Raizner, A; Wechsler, L,期刊：New England Journal of Medicine, 页码：991-999 , 文章类型： Article，,卷期：2012年366-11]
- Background The prevalence of patent foramen ovale among patients with cryptogenic stroke is higher than that in the general population. Closure with a percutaneous device is often recommended in such patients, but it is ...
- Prostate-Cancer Mortality at 11 Years of Follow-up
[作者：Schroder, FH; Hugosson, J; Roobol, MJ; Tammela, TLJ; Ciatto, S; Nelen, V; Kwiatkowski, M; Lujan, M; Lilja, H; Zappa, M; Denis, LJ; Recker, F; Paez, A; Maattanen, L; Bangma, CH; Aus, G; Carlsson, S; Villers, A; Rebillard, X; van der Kwast, T; Kujala, PM; Blijenberg, BG; Stenman, UH; Huber, A; Taari, K; Hakama, M; Moss, SM; de Koning, HJ; Auvinen, A,期刊：New England Journal of Medicine, 页码：981-990 , 文章类型： Article，,卷期：2012年366-11]
- Background Several trials evaluating the effect of prostate-specific antigen (PSA) testing on prostate-cancer mortality have shown conflicting results. We updated prostate-cancer mortality in the European Randomized Stud...
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