- Vorapaxar in the Secondary Prevention of Atherothrombotic Events
[作者：Morrow, DA; Braunwald, E; Bonaca, MP; Ameriso, SF; Dalby, AJ; Fish, MP; Fox, KAA; Lipka, LJ; Liu, X; Nicolau, JC; Ophuis, AJO; Paolasso, E; Scirica, BM; Spinar, J; Theroux, P; Wiviott, SD; Strony, J; Murphy, SA,期刊：New England Journal of Medicine, 页码：1404-1413 , 文章类型： Article，,卷期：2012年366-15]
- BACKGROUND Thrombin potently activates platelets through the protease-activated receptor PAR-1. Vorapaxar is a novel antiplatelet agent that selectively inhibits the cellular actions of thrombin through antagonism of PAR...
- Case 11-2012: A 60-Year-Old Man with Weakness, Rash, and Renal Failure Rocky Mountain spotted fever
[作者：Channick, RN; Lorenzo, ME; Wu, CC; Hoang, MP,期刊：New England Journal of Medicine, 页码：1434-1443 , 文章类型： Article，,卷期：2012年366-15]
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- Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
[作者：Ledermann, J; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; Scott, C; Meier, W; Shapira-Frommer, R; Safra, T; Matei, D; Macpherson, E; Watkins, C; Carmichael, J; Matulonis, U,期刊：New England Journal of Medicine, 页码：1382-1392 , 文章类型： Article，,卷期：2012年366-15]
- BACKGROUND Olaparib (AZD2281) is an oral poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitor that has shown antitumor activity in patients with high-grade serous ovarian cancer with or without BRCA1 or BRCA2 ge...
- Outcomes after Induction Failure in Childhood Acute Lymphoblastic Leukemia
[作者：Schrappe, M; Hunger, SP; Pui, CH; Saha, V; Gaynon, PS; Baruchel, A; Conter, V; Otten, J; Ohara, A; Versluys, AB; Escherich, G; Heyman, M; Silverman, LB; Horibe, K; Mann, G; Camitta, BM; Harbott, J; Riehm, H; Richards, S; Devidas, M; Zimmermann, M,期刊：New England Journal of Medicine, 页码：1371-1381 , 文章类型： Article，,卷期：2012年366-15]
- BACKGROUND Failure of remission-induction therapy is a rare but highly adverse event in children and adolescents with acute lymphoblastic leukemia (ALL). METHODS We identified induction failure, defined by the persistenc...
- CT Angiography for Safe Discharge of Patients with Possible Acute Coronary Syndromes
[作者：Litt, HI; Gatsonis, C; Snyder, B; Singh, H; Miller, CD; Entrikin, DW; Leaming, JM; Gavin, LJ; Pacella, CB; Hollander, JE,期刊：New England Journal of Medicine, 页码：1393-1403 , 文章类型： Article，,卷期：2012年366-15]
- BACKGROUND Admission rates among patients presenting to emergency departments with possible acute coronary syndromes are high, although for most of these patients, the symptoms are ultimately found not to have a cardiac ...
- A Randomized Trial of Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
[作者：Elmunzer, BJ; Scheiman, JM; Lehman, GA; Chak, A; Mosler, P; Higgins, PDR; Hayward, RA; Romagnuolo, J; Elta, GH; Sherman, S; Waljee, AK; Repaka, A; Atkinson, MR; Cote, GA; Kwon, RS; McHenry, L; Piraka, CR; Wamsteker, EJ; Watkins, JL; Korsnes, SJ; Schmidt, SE; Turner, SM; Nicholson, S; Fogel, EL,期刊：New England Journal of Medicine, 页码：1414-1422 , 文章类型： Article，,卷期：2012年366-15]
- BACKGROUND Preliminary research suggests that rectally administered nonsteroidal antiinflammatory drugs may reduce the incidence of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). METHODS In thi...
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