- JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
[作者：Harrison, C; Kiladjian, JJ; Al-Ali, HK; Gisslinger, H; Waltzman, R; Stalbovskaya, V; McQuitty, M; Hunter, DS; Levy, R; Knoops, L; Cervantes, F; Vannucchi, AM; Barbui, T; Barosi, G,期刊：New England Journal of Medicine, 页码：787-798 , 文章类型： Article，,卷期：2012年366-9]
- BACKGROUND Treatment options for myelofibrosis are limited. We evaluated the efficacy and safety of ruxolitinib, a potent and selective Janus kinase (JAK) 1 and 2 inhibitor, as compared with the best available therapy, i...
- Placebo-Controlled Trial of Amantadine for Severe Traumatic Brain Injury
[作者：Giacino, JT; Whyte, J; Bagiella, E; Kalmar, K; Childs, N; Khademi, A; Eifert, B; Long, D; Katz, DI; Cho, S; Yablon, SA; Luther, M; Hammond, FM; Nordenbo, A; Novak, P; Mercer, W; Maurer-Karattup, P; Sherer, M,期刊：New England Journal of Medicine, 页码：819-826 , 文章类型： Article，,卷期：2012年366-9]
- BACKGROUND Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadi...
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
[作者：Verstovsek, S; Mesa, RA; Gotlib, J; Levy, RS; Gupta, V; DiPersio, JF; Catalano, JV; Deininger, M; Miller, C; Silver, RT; Talpaz, M; Winton, EF; Harvey, JH; Arcasoy, MO; Hexner, E; Lyons, RM; Paquette, R; Raza, A; Vaddi, K; Erickson-Viitanen, S; Koumenis, IL; Sun, W; Sandor, V; Kantarjian, HM,期刊：New England Journal of Medicine, 页码：799-807 , 文章类型： Article，,卷期：2012年366-9]
- BACKGROUND Ruxolitinib, a selective inhibitor of Janus kinase (JAK) 1 and 2, has clinically significant activity in myelofibrosis. METHODS In this double-blind trial, we randomly assigned patients with intermediate-2 or ...
- A Randomized Trial of Nicotine-Replacement Therapy Patches in Pregnancy
[作者：Coleman, T; Cooper, S; Thornton, JG; Grainge, MJ; Watts, K; Britton, J; Lewis, S,期刊：New England Journal of Medicine, 页码：808-818 , 文章类型： Article，,卷期：2012年366-9]
- BACKGROUND Nicotine-replacement therapy is effective for smoking cessation outside pregnancy and its use is widely recommended during pregnancy. We investigated the efficacy and safety of nicotine patches during pregnanc...
- A Startling Decline
[作者：Rinne, ML; McGinnis, SM; Samuels, MA; Katz, JT; Loscalzo, J,期刊：New England Journal of Medicine, 页码：836-842 , 文章类型： Article，,卷期：2012年366-9]
- An 89-year-old man was brought to the emergency department by his wife and son for an evaluation of changes in cognition and personality. Six months earlier, he began to require help managing finances and operating his c...
|