- Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells
[作者:Zhu, Q; Shan, XH; Miao, H; Lu, YB; Xu, JR; You, N; Liu, C; Liao, DF; Jin, JF,期刊:FEBS Letters, 页码:2136-2141 , 文章类型: Article,,卷期:2009年583-12]
- Ceramidase hydrolyzes ceramide and produces sphingosine as a substrate of sphingosine kinase (SPHK), which transforms sphingosine to sphingosine-1-phosphate. It has been reported that cytokines elicit SPHK activation in ...
- The PsbP protein, but not the PsbQ protein, is required for normal thylakoid architecture in Arabidopsis thaliana
[作者:Yi, XP; Hargett, SR; Frankel, LK; Bricker, TM,期刊:FEBS Letters, 页码:2142-2147 , 文章类型: Article,,卷期:2009年583-12]
- Interfering RNA was used to suppress the expression of the genes At1g06680 and At2g30790 in Arabidopsis thaliana, which encode the PsbP-1 and PsbP-2 proteins, respectively, of Photosystem II. A phenotypic series of trans...
- Individual and common inhibitors of coronavirus and picornavirus main proteases (vol 583, pg 549, 2009)
[作者:Kuo, CJ; Liu, HG; Lo, YK; Seong, CM; Lee, KI; Jung, YS; Liang, PH,期刊:FEBS Letters, 页码:2154-2154 , 文章类型: Correction,,卷期:2009年583-12]
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- Evolution of geminiviruses and their satellites
[作者:Nawaz-Ul-Rehman, MS; Fauquet, CM,期刊:FEBS Letters, 页码:1825-1832 , 文章类型: Review,,卷期:2009年583-12]
- Geminiviruses and their satellites have circular single stranded DNA genomes, infecting many crops and weeds across the globe. To successfully invade new hosts, break host resistance, move virus particles within and betw...
- Activity of the circadian transcription factor White Collar Complex is modulated by phosphorylation of SP-motifs
[作者:Sancar, G; Sancar, C; Brunner, M; Schafmeier, T,期刊:FEBS Letters, 页码:1833-1840 , 文章类型: Article,,卷期:2009年583-12]
- Posttranslational modi. cations, particularly phosphorylation, regulate activity, stability and localization of proteins in circadian clocks, thereby contributing to a stable oscillation with a period of approximately 24...
- Phosphoglycerate mutase in mammalian striated muscles: Subcellular localization and binding partners
[作者:Kowalski, W; Gizak, A; Rakus, D,期刊:FEBS Letters, 页码:1841-1845 , 文章类型: Article,,卷期:2009年583-12]
- Contrary to previously published data, we have found that in mammalian skeletal muscles, phosphoglycerate mutase (PGM) is organized in a regular, striated fashion within the sarcomere. In the absence of the enzyme effect...
- Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
[作者:Waters, S; Marchbank, K; Solomon, E; Whitehouse, C; Gautel, M,期刊:FEBS Letters, 页码:1846-1852 , 文章类型: Article,,卷期:2009年583-12]
- Nbr1, a ubiquitous kinase scaffold protein, contains a PB1, and a ubiquitin-associated (UBA) domain. We show here that the nbr1 UBA domain binds to lysine-48 and -63 linked polyubiquitin-B chains. Nbr1 also binds to the ...
- Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation
[作者:Davies, SMK; Rackham, O; Shearwood, AMJ; Hamilton, KL; Narsai, R; Whelan, J; Filipovska, A,期刊:FEBS Letters, 页码:1853-1858 , 文章类型: Article,,卷期:2009年583-12]
- The basic components and mechanisms of mitochondrial transcription in mammals have been described, however, the components involved in mRNA processing, translation and stability remain largely unknown. In plants, pentatr...
- Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID mice
[作者:Jin, L; Xiao, CL; Lu, CH; Xia, M; Xing, GW; Xiong, S; Liu, QY; Liu, H; Li, YC; Ge, F; Wang, QD; He, QY; Wang, YF,期刊:FEBS Letters, 页码:1859-1866 , 文章类型: Article,,卷期:2009年583-12]
SNX-2112, a novel inhibitor of Hsp90 currently used as an anti-tumor drug, induces apoptosis in multiple tumor cell lines. It destabilizes specific client proteins, but the molecular mechanism of the apoptosis effect ...
- Detection of c-Abl kinase-promoted phosphorylation of Rad51 by specific antibodies reveals that Y54 phosphorylation is dependent on that of Y315
[作者:Popova, M; Shimizu, H; Yamamoto, KI; Lebechec, M; Takahashi, M; Fleury, F,期刊:FEBS Letters, 页码:1867-1872 , 文章类型: Article,,卷期:2009年583-12]
- Rad51 plays a crucial role in homologous recombination and recombinational DNA repair. Its activity is regulated by phosphorylation by the c-Abl kinase. Either Tyr54 or Tyr315 have been reported as the target of phosphor...
- The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription
[作者:Kang, HB; Choi, Y; Lee, JM; Choi, KC; Kim, HC; Yoo, JY; Lee, YH; Yoon, HG,期刊:FEBS Letters, 页码:1880-1886 , 文章类型: Article,,卷期:2009年583-12]
- In this study, we discovered that NSD2 specifically interacts with the DNA-binding domain of androgen receptor (AR) via its HMG domain, and the nuclear translocation of both NSD2 and AR is enhanced in the presence of lig...
- Maize AKIN beta gamma dimerizes through the KIS/CBM domain and assembles into SnRK1 complexes
[作者:Lopez-Paz, C; Vilela, B; Riera, M; Pages, M; Lumbreras, V,期刊:FEBS Letters, 页码:1887-1894 , 文章类型: Article,,卷期:2009年583-12]
- The SNF1/AMPK/SnRK1 complex is an intracellular energy sensor composed of three types of subunits: the SnRK1 kinase and two regulatory, non-catalytic subunits (designated beta and gamma). We have previously described an ...
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