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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Spiralian quartet developmental potential is regulated by specific localization elements that mediate asymmetric RNA segregation [作者：Rabinowitz, JS; Lambert, JD,期刊：Development, 页码：4039-4049 , 文章类型： Article，,卷期：2010年137-23] Spiralian embryos are found in a large group of invertebrate phyla but are largely uncharacterized at a molecular level. These embryos are thought to be particularly reliant on autonomous cues for patterning, and thus re... A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning [作者：Lek, M; Dias, JM; Marklund, U; Uhde, CW; Kurdija, S; Lei, QB; Sussel, L; Rubenstein, JL; Matise, MP; Arnold, HH; Jessell, TM; Ericson, J,期刊：Development, 页码：4051-4060 , 文章类型： Article，,卷期：2010年137-23] The deployment of morphogen gradients is a core strategy to establish cell diversity in developing tissues, but little is known about how small differences in the concentration of extracellular signals are translated int... Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome [作者：Hofmann, JJ; Zovein, AC; Koh, H; Radtke, F; Weinmaster, G; Iruela-Arispe, ML,期刊：Development, 页码：4061-4072 , 文章类型： Article，,卷期：2010年137-23] Mutations in the human Notch ligand jagged 1 (JAG1) result in a multi-system disorder called Alagille syndrome (AGS). AGS is chiefly characterized by a paucity of intrahepatic bile ducts (IHBD), but also includes cardiac... Prohibitin1 acts as a neural crest specifier in Xenopus development by repressing the transcription factor E2F1 [作者：Schneider, M; Schambony, A; Wedlich, D,期刊：Development, 页码：4073-4081 , 文章类型： Article，,卷期：2010年137-23] Prohibitin 1 (phb1), which was initially described as an inhibitor of cell proliferation, is a highly conserved protein found in multiple cellular compartments. In the nucleus it interacts with the transcriptional regula... Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation [作者：Zhan, SA; Guo, QH; Li, MH; Li, MW; Li, JY; Miao, XX; Huang, YP,期刊：Development, 页码：4083-4090 , 文章类型： Article，,卷期：2010年137-23] The pigmentation of insects has served as an excellent model for the study of morphological trait evolution and developmental biology. The melanism (mln) mutant of the silkworm Bombyx mori is notable for its strong black... When whorls collide: the development of hair patterns in frizzled 6 mutant mice [作者：Wang, YS; Chang, H; Nathans, J,期刊：Development, 页码：4091-4099 , 文章类型： Article，,卷期：2010年137-23] Surface appendages such as bristles, feathers and hairs exhibit both long-and short-range order. In the frizzled 6 null (Fz6(-/-)) mouse the orientations of the earliest born hair follicles are uncorrelated, but over tim... Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex [作者：Yokota, Y; Eom, TY; Stanco, A; Kim, WY; Rao, S; Snider, WD; Anton, ES,期刊：Development, 页码：4101-4110 , 文章类型： Article，,卷期：2010年137-23] Polarized radial glia are crucial to the formation of the cerebral cortex. They serve as neural progenitors and as guides for neuronal placement in the developing cerebral cortex. The maintenance of polarized morphology ... Sry: the master switch in mammalian sex determination [作者：Kashimada, K; Koopman, P,期刊：Development, 页码：3921-3930 , 文章类型： Article，,卷期：2010年137-23] SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex determination. Recent studies in mice reveal that the major role of SRY is to achieve sufficient expression of the related gene Sox9, in order to... Clonal analyses reveal roles of organ founding stem cells, melanocyte stem cells and melanoblasts in establishment, growth and regeneration of the adult zebrafish fin [作者：Tu, S; Johnson, SL,期刊：Development, 页码：3931-3939 , 文章类型： Article，,卷期：2010年137-23] In vertebrates, the adult form emerges from the embryo by mobilization of precursors or adult stem cells. What different cell types these precursors give rise to, how many precursors establish the tissue or organ, and ho... Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse [作者：Sasaki, T; Mizuochi, C; Horio, Y; Nakao, K; Akashi, K; Sugiyama, D,期刊：Development, 页码：3941-3952 , 文章类型： Article，,卷期：2010年137-23] Hematopoietic stem cells (HSCs) emerge from and expand in the mouse placenta at mid-gestation. To determine their compartment of origin and define extrinsic signals governing their commitment to this lineage, we identifi... Klf5 regulates lineage formation in the pre-implantation mouse embryo [作者：Lin, SCJ; Wani, MA; Whitsett, JA; Wells, JM,期刊：Development, 页码：3953-3963 , 文章类型： Article，,卷期：2010年137-23] Kruppel-like transcription factors (Klfs) are essential for the induction and maintenance of pluripotency of embryonic stem cells (ESCs), yet little is known about their roles in establishing the three lineages of the pr... Identification of epidermal progenitors for the Merkel cell lineage [作者：Woo, SH; Stumpfova, M; Jensen, UB; Lumpkin, EA; Owens, DM,期刊：Development, 页码：3965-3971 , 文章类型： Article，,卷期：2010年137-23] Epithelial stem cells in adult mammalian skin are known to maintain epidermal, follicular and sebaceous lineages during homeostasis. Recently, Merkel cell mechanoreceptors were identified as a fourth lineage derived from... Role of canonical Wnt signaling/beta-catenin via Dermo1 in cranial dermal cell development [作者：Tran, TH; Jarrell, A; Zentner, GE; Welsh, A; Brownell, I; Scacheri, PC; Atit, R,期刊：Development, 页码：3973-3984 , 文章类型： Article，,卷期：2010年137-23] Cranial dermis develops from cephalic mesoderm and neural crest cells, but what signal(s) specifies the dermal lineage is unclear. Using genetic tools to fate map and manipulate a cranial mesenchymal progenitor populatio... Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning [作者：Martin, SM; O'Brien, GS; Portera-Cailliau, C; Sagasti, A,期刊：Development, 页码：3985-3994 , 文章类型： Article，,卷期：2010年137-23] Fragments of injured axons that detach from their cell body break down by the molecularly regulated process of Wallerian degeneration (WD). Although WD resembles local axon degeneration, a common mechanism for refining n... The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo [作者：Beatty, A; Morton, D; Kemphues, K,期刊：Development, 页码：3995-4004 , 文章类型： Article，,卷期：2010年137-23] Polarity is essential for generating cell diversity. The one-cell C. elegans embryo serves as a model for studying the establishment and maintenance of polarity. In the early embryo, a myosin II-dependent contraction of ... Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo [作者：Panagiotaki, N; Dajas-Bailador, F; Amaya, E; Papalopulu, N; Dorey, K,期刊：Development, 页码：4005-4015 , 文章类型： Article，,卷期：2010年137-23] During development, many organs, including the kidney, lung and mammary gland, need to branch in a regulated manner to be functional. Multicellular branching involves changes in cell shape, proliferation and migration. A...