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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Recombineering Hunchback identifies two conserved domains required to maintain neuroblast competence and specify early-born neuronal identity [作者：Tran, KD; Miller, MR; Doe, CQ,期刊：Development, 页码：1421-1430 , 文章类型： Article，,卷期：2010年137-9] The Hunchback/Ikaros family of zinc-finger transcription factors is essential for specifying the anterior/posterior body axis in insects, the fate of early-born pioneer neurons in Drosophila, and for retinal and immune d... Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing Delta Np63 alpha [作者：Romano, RA; Smalley, K; Liu, S; Sinha, S,期刊：Development, 页码：1431-1439 , 文章类型： Article，,卷期：2010年137-9] The transcription factor p63 plays an essential role in epidermal morphogenesis. Animals lacking p63 fail to form many ectodermal organs, including the skin and hair follicles. Although the indispensable role of p63 in s... The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules [作者：Voronina, E; Seydoux, G,期刊：Development, 页码：1441-1450 , 文章类型： Article，,卷期：2010年137-9] C. elegans P granules are conserved cytoplasmic ribonucleoprotein complexes that are unique to the germline and essential for fertility. During most of germline development, P granules are perinuclear and associate with ... The FoxF/FoxC factor LET-381 directly regulates both cell fate specification and cell differentiation in C. elegans mesoderm development [作者：Amin, NM; Shi, HR; Liu, J,期刊：Development, 页码：1451-1460 , 文章类型： Article，,卷期：2010年137-9] Forkhead transcription factors play crucial and diverse roles in mesoderm development. In particular, FoxF and FoxC genes are, respectively, involved in the development of visceral/splanchnic mesoderm and non-visceral... RBPj kappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development [作者：Dong, YF; Jesse, AM; Kohn, A; Gunnell, LM; Honjo, T; Zuscik, MJ; O'Keefe, RJ; Hilton, MJ,期刊：Development, 页码：1461-1471 , 文章类型： Article，,卷期：2010年137-9] The Notch pathway has recently been implicated in mesenchymal progenitor cell (MPC) differentiation from bone marrow-derived progenitors. However, whether Notch regulates MPC differentiation in an RBPj kappa-dependent ma... Membrane fusion triggers rapid degradation of two gamete-specific, fusion-essential proteins in a membrane block to polygamy in Chlamydomonas [作者：Liu, YJ; Misamore, MJ; Snell, WJ,期刊：Development, 页码：1473-1481 , 文章类型： Article，,卷期：2010年137-9] The plasma membranes of gametes are specialized for fusion, yet, once fusion occurs, in many organisms the new zygote becomes incapable of further membrane fusion reactions. The molecular mechanisms that underlie this lo... Functional specialization of cellulose synthase genes of prokaryotic origin in chordate larvaceans [作者：Sagane, Y; Zech, K; Bouquet, JM; Schmid, M; Bal, U; Thompson, EM,期刊：Development, 页码：1483-1492 , 文章类型： Article，,卷期：2010年137-9] Extracellular matrices play important, but poorly investigated, roles in morphogenesis. Extracellular cellulose is central to regulation of pattern formation in plants, but among metazoans only tunicates are capable of c... Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability [作者：Duchi, S; Fagnocchi, L; Cavaliere, V; Hsouna, A; Gargiulo, G; Hsu, T,期刊：Development, 页码：1493-1503 , 文章类型： Article，,卷期：2010年137-9] Mutations in the human von Hippel-Lindau (VHL) genes are the cause of VHL disease, which displays multiple benign and malignant tumors. The VHL gene has been shown to regulate angiogenic potential and glycolic metabolism... Limited functions of Hox genes in the larval development of the ascidian Ciona intestinalis [作者：Ikuta, T; Satoh, N; Saiga, H,期刊：Development, 页码：1505-1513 , 文章类型： Article，,卷期：2010年137-9] In animals, region specific morphological characters along the anteroposterior axis are controlled by a number of developmental genes, including Hox genes encoding homeodomain transcription factors. Although Hox genes ha... The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite [作者：Oginuma, M; Takahashi, Y; Kitajima, S; Kiso, M; Kanno, J; Kimura, A; Saga, Y,期刊：Development, 页码：1515-1522 , 文章类型： Article，,卷期：2010年137-9] Notch signaling exerts multiple roles during different steps of mouse somitogenesis. We have previously shown that segmental boundaries are formed at the interface of the Notch activity boundary, suggesting the importanc... JACKDAW controls epidermal patterning in the Arabidopsis root meristem through a non-cell-autonomous mechanism [作者：Hassan, H; Scheres, B; Blilou, I,期刊：Development, 页码：1523-1529 , 文章类型： Article，,卷期：2010年137-9] In Arabidopsis, specification of the hair and non-hair epidermal cell types is position dependent, in that hair cells arise over clefts in the underlying cortical cell layer. Epidermal patterning is determined by a netwo... Mesodermal Wnt signaling organizes the neural plate via Meis3 [作者：Elkouby, YM; Elias, S; Casey, ES; Blythe, SA; Tsabar, N; Klein, PS; Root, H; Liu, KJ; Frank, D,期刊：Development, 页码：1531-1541 , 文章类型： Article，,卷期：2010年137-9] In vertebrates, canonical Wnt signaling controls posterior neural cell lineage specification. Although Wnt signaling to the neural plate is sufficient for posterior identity, the source and timing of this activity remain... Ets1 is required for proper migration and differentiation of the cardiac neural crest [作者：Gao, ZG; Kim, GH; Mackinnon, AC; Flagg, AE; Bassett, B; Earley, JU; Svensson, EC,期刊：Development, 页码：1543-1551 , 文章类型： Article，,卷期：2010年137-9] Defects in cardiac neural crest lead to congenital heart disease through failure of cardiac outflow tract and ventricular septation. In this report, we demonstrate a previously unappreciated role for the transcription fa... FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation [作者：Roth, M; Bonev, B; Lindsay, J; Lea, R; Panagiotaki, N; Houart, C; Papalopulu, N,期刊：Development, 页码：1553-1562 , 文章类型： Article，,卷期：2010年137-9] FoxG1 is a conserved transcriptional repressor that plays a key role in the specification, proliferation and differentiation of the telencephalon, and is expressed from the earliest stages of telencephalic development th... von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina [作者：Kurihara, T; Kubota, Y; Ozawa, Y; Takubo, K; Noda, K; Simon, MC; Johnson, RS; Suematsu, M; Tsubota, K; Ishida, S; Goda, N; Suda, T; Okano, H,期刊：Development, 页码：1563-1571 , 文章类型： Article，,卷期：2010年137-9] In early neonates, the fetal circulatory system undergoes dramatic transition to the adult circulatory system. Normally, embryonic connecting vessels, such as the ductus arteriosus and the foramen ovale, close and regres... Hepatocyte nuclear factor 1 alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium [作者：D'Angelo, A; Bluteau, O; Garcia-Gonzalez, MA; Gresh, L; Doyen, A; Garbay, S; Robine, S; Pontoglio, M,期刊：Development, 页码：1573-1582 , 文章类型： Article，,卷期：2010年137-9] The intestinal epithelium is a complex system characterized by massive and continuous cell renewal and differentiation. In this context, cell-type-specific transcription factors are thought to play a crucial role by modu...