- Consensus Substrate Sequence for Protein-tyrosine Phosphatase Receptor Type Z
[作者：Fujikawa, A; Fukada, M; Makioka, Y; Suzuki, R; Chow, JPH; Matsumoto, M; Noda, M,期刊：Journal of Biological Chemistry, 页码：37137-37146 , 文章类型： Article，,卷期：2011年286-43]
- Protein-tyrosine phosphatase receptor type Z (Ptprz) has multiple substrate proteins, including G protein-coupled receptor kinase-interactor 1 (Git1), membrane-associated guanylate kinase, WW and PDZ domain-containing 1 ...
- The E3 Ubiquitin Ligase Mind Bomb-2 (MIB2) Protein Controls B-cell CLL/Lymphoma 10 (BCL10)-dependent NF-kappa B Activation
[作者：Stempin, CC; Chi, LY; Giraldo-Vela, JP; High, AA; Hacker, H; Redecke, V,期刊：Journal of Biological Chemistry, 页码：37147-37157 , 文章类型： Article，,卷期：2011年286-43]
- B-cell CLL/lymphoma 10 (BCL10) is crucial for the activation of NF-kappa B in numerous immune receptor signaling pathways, including the T-cell receptor (TCR) and B-cell receptor signaling pathways. However, the molecula...
- Cysteine Cathepsins S and L Modulate Anti-angiogenic Activities of Human Endostatin
[作者：Veillard, F; Saidi, A; Burden, RE; Scott, CJ; Gillet, L; Lecaille, F; Lalmanach, G,期刊：Journal of Biological Chemistry, 页码：37158-37167 , 文章类型： Article，,卷期：2011年286-43]
- Human endostatin, a potent anti-angiogenic protein, is generated by release of the C terminus of collagen XVIII. Here, we propose that cysteine cathepsins are involved in both the liberation and activation of bioactive e...
- Ubiquitin-mediated Regulation of CD86 Protein Expression by the Ubiquitin Ligase Membrane-associated RING-CH-1 (MARCH1)
[作者：Corcoran, K; Jabbour, M; Bhagwandin, C; Deymier, MJ; Theisen, DL; Lybarger, L,期刊：Journal of Biological Chemistry, 页码：37168-37180 , 文章类型： Article，,卷期：2011年286-43]
- The activation of naive T cells requires antigen presentation by dendritic cells (DCs), and the process of antigen presentation is regulated over the course of DC maturation. One key aspect of this regulation is the cell...
- Novel gamma-Secretase Enzyme Modulators Directly Target Presenilin Protein
[作者：Ebke, A; Luebbers, T; Fukumori, A; Shirotani, K; Haass, C; Baumann, K; Steiner, H,期刊：Journal of Biological Chemistry, 页码：37181-37186 , 文章类型： Article，,卷期：2011年286-43]
- gamma-Secretase is essential for the generation of the neurotoxic 42-amino acid amyloid beta-peptide (A beta(42)). The aggregation-prone hydrophobic peptide, which is deposited in Alzheimer disease (AD) patient brain, is...
- High Throughput Short Interfering RNA (siRNA) Screening of the Human Kinome Identifies Novel Kinases Controlling the Canonical Nuclear Factor-kappa B (NF-kappa B) Activation Pathway
[作者：Choudhary, S; Rosenblatt, KP; Fang, L; Tian, B; Wu, ZH; Brasier, AR,期刊：Journal of Biological Chemistry, 页码：37187-37195 , 文章类型： Article，,卷期：2011年286-43]
- Nuclear factor-kappa B (NF-kappa B) is an inducible cytoplasmic transcription factor that plays a role as a master regulator of airway mucosal inflammation. The prototypical ("canonical") NF-kappa B pathway controls cyto...
- 5-Aza-2 '-deoxycytidine Activates Iron Uptake and Heme Biosynthesis by Increasing c-Myc Nuclear Localization and Binding to the E-boxes of Transferrin Receptor 1 (TfR1) and Ferrochelatase (Fech) Genes
[作者：Ning, B; Liu, G; Liu, YY; Su, XF; Anderson, GJ; Zheng, X; Chang, Y; Guo, MZ; Liu, YF; Zhao, YL; Nie, GJ,期刊：Journal of Biological Chemistry, 页码：37196-37206 , 文章类型： Article，,卷期：2011年286-43]
- The hypomethylating agent 5-aza-2'-deoxycytidine (5-aza-CdR) and its derivatives have been successfully used for the treatment of myelodysplastic syndromes, and they frequently improve the anemia that usually accompanies...
- Characterization of Cholix Toxin-induced Apoptosis in HeLa Cells
[作者：Ogura, K; Yahiro, K; Tsutsuki, H; Nagasawa, S; Yamasaki, S; Moss, J; Noda, M,期刊：Journal of Biological Chemistry, 页码：37207-37215 , 文章类型： Article，,卷期：2011年286-43]
- Cholix toxin (Cholix) is a novel ADP-ribosylating cytotoxin produced by Vibrio cholerae, which utilizes eukaryotic elongation factor 2 as a substrate and acts by a mechanism similar to that of diphtheria toxin and Pseudo...
- Chemokine CXCL12 Uses CXCR4 and a Signaling Core Formed by Bifunctional Akt, Extracellular Signal-regulated Kinase (ERK) 1/2, and Mammalian Target of Rapamycin Complex 1 (mTORC1) Proteins to Control Chemotaxis and Survival Simultaneously in Mature Dendritic Cells
[作者：Delgado-Martin, C; Escribano, C; Pablos, JL; Riol-Blanco, L; Rodriguez-Fernandez, JL,期刊：Journal of Biological Chemistry, 页码：37222-37236 , 文章类型： Article，,卷期：2011年286-43]
- Chemokines control several cell functions in addition to chemotaxis. Although much information is available on the involvement of specific signaling molecules in the control of single functions controlled by chemokines, ...
- Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria meningitidis
[作者：Lin, LYC; Rakic, B; Chiu, CPC; Lameignere, E; Wakarchuk, WW; Withers, SG; Strynadka, NCJ,期刊：Journal of Biological Chemistry, 页码：37237-37248 , 文章类型： Article，,卷期：2011年286-43]
- The first x-ray crystallographic structure of a CAZY family-52 glycosyltransferase, that of the membrane associated alpha 2,3/alpha 2,6 lipooligosaccharide sialyltransferase from Neisseria meningitidis serotype L1 (NST),...
- Analysis of Two Major Intracellular Phospholipases A(2) (PLA(2)) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA(2)alpha, Not Ca(2+)-independent PLA(2)beta, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts
[作者：Ueno, N; Taketomi, Y; Yamamoto, K; Hirabayashi, T; Kamei, D; Kita, Y; Shimizu, T; Shinzawa, K; Tsujimoto, Y; Ikeda, K; Taguchi, R; Murakamia, M,期刊：Journal of Biological Chemistry, 页码：37249-37263 , 文章类型： Article，,卷期：2011年286-43]
- Mast cells release a variety of mediators, including arachidonic acid (AA) metabolites, to regulate allergy, inflammation, and host defense, and their differentiation and maturation within extravascular microenvironments...
- Two-pore Channels Form Homo- and Heterodimers
[作者：Rietdorf, K; Funnell, TM; Ruas, M; Heinemann, J; Parrington, J; Galione, A,期刊：Journal of Biological Chemistry, 页码：37058-37062 , 文章类型： Article，,卷期：2011年286-43]
- Two-pore channels (TPCs) have been recently identified as NAADP-regulated Ca(2+) release channels, which are localized on the endolysosomal system. TPCs have a 12-transmembrane domain (TMD) structure and are evolutionary...
- Genomic Analyses of the RNA-binding Protein Hu Antigen R (HuR) Identify a Complex Network of Target Genes and Novel Characteristics of Its Binding Sites
[作者：Uren, PJ; Burns, SC; Ruan, JH; Singh, KK; Smith, AD; Penalva, LOF,期刊：Journal of Biological Chemistry, 页码：37063-37066 , 文章类型： Article，,卷期：2011年286-43]
- The ubiquitously expressed RNA-binding protein Hu antigen R (HuR) or ELAVL1 is implicated in a variety of biological processes as well as being linked with a number of diseases, including cancer. Despite a great deal of ...
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