- CD4(+)CD25(+) regulatory T cells: a therapeutic target for liver diseases
[作者:Zheng, MH; Gu, DN; Braddock, M; Leishman, AJ; Jin, C; Wen, JS; Gong, YW; Chen, YP,期刊:Expert Opinion on Therapeutic Targets, 页码:313-326 , 文章类型: Review,,卷期:2008年12-3]
- Background: Regulatory T cells (T-regs) have been shown to play an important role in maintaining peripheral immune homeostasis by suppressing autoreactive and allergen-specific T cells and turning off the immune response...
- Therapeutic targets in hypertension: is there a place for antagonists of the most potent vasoconstrictors?
[作者:Giachini, FRC; Callera, GE; Carneiro, FS; Tostes, RC; Webb, RC,期刊:Expert Opinion on Therapeutic Targets, 页码:327-339 , 文章类型: Review,,卷期:2008年12-3]
- Background: Endothelin-1 (ET-1) and urotensin II (U-II) are the most potent and unusually long-lasting constrictors of human vessels known to date. Objective: In this review, we focus on the vascular effects of endotheli...
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