- Initiation of protein synthesis: a target for antimicrobials
[作者:Brandi, L; Fabbretti, A; Pon, CL; Dahlberg, AE; Gualerzi, CO,期刊:Expert Opinion on Therapeutic Targets, 页码:519-534 , 文章类型: Review,,卷期:2008年12-5]
- Background: Translation initiation is a basic and universal biological process that employs significantly different components and displays substantially different mechanisms in bacterial, archaeal and eukaryotic cells. ...
- Small interfering RNA therapy in cancer: mechanism, potential targets, and clinical applications
[作者:Huang, C; Li, M; Chen, CY; Yao, QZ,期刊:Expert Opinion on Therapeutic Targets, 页码:637-645 , 文章类型: Review,,卷期:2008年12-5]
- Background: Small interfering RNA (siRNA) has become a powerful tool in knocking down or silencing gene expression in most cells. siRNA-based therapy has shown great promise for many diseases such as cancer. Major target...
- The P2X(7) receptor as a therapeutic target
[作者:Romagnoli, R; Baraldi, PG; Cruz-Lopez, O; Lopez-Cara, C; Preti, D; Borea, PA; Gessi, S,期刊:Expert Opinion on Therapeutic Targets, 页码:647-661 , 文章类型: Review,,卷期:2008年12-5]
- Background: The P2X7 receptor is present in a variety of cell types involved in pain, inflammatory processes and neuroclegenerative conditions, thus it may be an appealing target for pharmacological intervention. The ext...
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