- B cells in cluster or in a scattered pattern do not correlate with clinical outcome of renal allograft rejection
[作者:Scheepstra, C; Bemelman, FJ; van der Loos, C; Rowshani, AT; van Donselaar-Van der Pant, KAMI; Idu, MM; ten Berge, IJM; Florquin, S,期刊:Transplantation, 页码:772-778 , 文章类型: Article,,卷期:2008年86-6]
- Background. The role of CD20+ B cells in renal allograft rejection has been reappreciated. Importantly, recent Studies suggest a relation between CD20+ B cell aggregates and poorer clinical outcome. In the present study,...
- Impact of VKORC1 haplotypes on long-term graft function in kidney transplantation
[作者:Quteineh, L; Verstuyft, C; Durrbach, A; Letierce, A; Ferlicot, S; Charpentier, B; Becquemont, L,期刊:Transplantation, 页码:779-783 , 文章类型: Article,,卷期:2008年86-6]
- Background. Chronic allograft injury is the major cause of renal allograft loss after the first year of transplantation. Vitamin K epoxide reductase complex subunit I (VKORC1) haplotype combinations were found to be asso...
- Incidence and risk factors for hepatocellular carcinoma after solid organ transplantation
[作者:Hoffmann, CJ; Subramanian, AK; Cameron, AM; Engels, EA,期刊:Transplantation, 页码:784-790 , 文章类型: Article,,卷期:2008年86-6]
- Background. Solid organ transplant recipients commonly are infected with hepatitis viruses, are immunosuppressed, and have other potential hepatocellular carcinoma (HCC) risk factors.Methods. We studied de novo HCC incid...
- Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant
[作者:Alexander, BD; Perfect, JR; Daly, JS; Restrepo, A; Tobon, AM; Patino, H; Hardalo, CJ; Graybill, JR,期刊:Transplantation, 页码:791-796 , 文章类型: Article,,卷期:2008年86-6]
- Background. The incidence of invasive fungal infections (IFIs) in solid organ transplant (SOT) recipients has increased during the past 20 years and is associated with significant morbidity and mortality. In this post ho...
- Antirejection treatment in kidney transplant patients with BK viruria
[作者:Kayler, LK; Batal, I; Mohanka, R; Morgan, C; Basu, A; Shapiro, R; Randhawa, PS,期刊:Transplantation, 页码:797-803 , 文章类型: Article,,卷期:2008年86-6]
- Background. Kidney transplant recipients with BK virus nephropathy or viremia are generally treated with reduction of immunosuppression to facilitate virus eradication.Methods. Prompted by biopsy findings interpreted as ...
- The utility of a specific measure for heart transplant patients: Reliability and validity of the Kansas City Cardiomyopathy Questionnaire
[作者:Ortega, T; Diaz-Molina, B; Montoliu, MA; Ortega, F; Valdes, C; Rebollo, P; Almenar, M; Iscar, M,期刊:Transplantation, 页码:804-810 , 文章类型: Article,,卷期:2008年86-6]
- Background. Health-Related Quality of Life of patients with heart transplantation is an important variable; however, it has received little attention so far, and only two Spanish validated measurement instruments are ava...
- Interstitial inflammatory lesions of the pulmonary allograft: A retrospective analysis of 2697 transbronchial biopsies
[作者:Burton, CM; Iversen, M; Carlsen, J; Andersen, CB,期刊:Transplantation, 页码:811-819 , 文章类型: Article,,卷期:2008年86-6]
- Background. Parenchymal and bronchial inflammatory and fibrotic lesions other than acute cellular rejection (ACR) and lymphocytic bronchiolitis are prevalent; however, the context in which they appear is unknown, and oft...
- Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy
[作者:Reinsmoen, NL; Lai, CH; Vo, A; Cao, K; Ong, G; Naim, M; Wang, Q; Jordan, SC,期刊:Transplantation, 页码:820-825 , 文章类型: Article,,卷期:2008年86-6]
- Background. The aims of this study were to determine the level of donor-specific antibody (DSA) that allows for Successful transplantation after desensitization with IVIG and rituximab and to identify patients at risk fo...
- UL40 human cytomegalovirus variability evolution patterns over time in renal transplant recipients
[作者:Garrigue, I; Corte, MFD; Magnin, N; Recordon-Pinson, P; Couzi, L; Lebrette, ME; Schrive, MH; Roncin, L; Taupin, JL; Deechanet-Merville, J; Fleury, H; Lafon, ME,期刊:Transplantation, 页码:826-835 , 文章类型: Article,,卷期:2008年86-6]
- Background. Human cytomegalovirus (HCMV) is the most common opportunistic pathogen infecting immunocompromised patients after transplantation. Although its immunomodulatory capacities and genomic variability participate ...
- PD-L1/PD-1 signal deficiency promotes allogeneic immune responses and accelerates heart allograft rejection
[作者:Wang, WG; Carper, K; Malone, F; Latchman, Y; Perkins, J; Fu, YW; Reyes, J; Li, W,期刊:Transplantation, 页码:836-844 , 文章类型: Article,,卷期:2008年86-6]
- Background. PD-L1, a ligand for programmed death 1 (PD-1), delivers a negative costimulatory signal to T cells and plays a critical role in the regulation of peripheral tolerance.Methods. We used PD-L1(-/-) mice to evalu...
- Functional recovery of chronic paraplegic pigs after autologous transplantation of bone marrow stromal cells
[作者:Zurita, M; Vaquero, J; Bonilla, C; Santos, M; De Haro, J; Oya, S; Aguayo, C,期刊:Transplantation, 页码:845-853 , 文章类型: Article,,卷期:2008年86-6]
- Background. Bone marrow stromal cells (BMSC) transplantation offers promise in the treatment of chronic paraplegia in rodents. Here, we report the effect of this cell therapy in adult pigs suffering chronic paraplegia.Me...
- In vitro suppression of xenoimmune-mediated macrophage activation by human CD4+CD25+ regulatory T cells
[作者:Fu, YL; Yi, SN; Wu, JJ; Jimenez, E; Simond, D; Hawthorne, WJ; O'Connell, PJ,期刊:Transplantation, 页码:865-874 , 文章类型: Article,,卷期:2008年86-6]
- Background. Macrophages are important effector cells in T cell-mediated xenograft rejection. The aim Of this study was to determine whether CD4+CD25+ regulatory T cells (Tregs) were capable of suppressing macrophage acti...
- Treatment of chronic steroid-refractory graft-versus-host disease with low-dose rituximab
[作者:von Bonin, M; Oelschlagel, U; Radke, J; Stewart, M; Ehninger, G; Bornhauser, M; Platzbecker, U,期刊:Transplantation, 页码:875-879 , 文章类型: Article,,卷期:2008年86-6]
- Rituximab, an anti-CD20 chimeric monoclonal antibody, is widely used in hematologic malignancies and has been introduced as a therapeutic option in autoimmune disorders. In recent studies, rituximab has shown promising a...
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