- Specific antioxidant selenoproteins are induced in the heart during hypertrophy
[作者:Hoffmann, FW; Hashimoto, AS; Lee, BC; Rose, AH; Shohet, RV; Hoffmann, PR,期刊:Archives of Biochemistry and Biophysics , 页码:38-44 , 文章类型: Article,,卷期:2011年512-1]
- Selenium (Se) is thought to confer cardioprotective effects through the actions of antioxidant selenoprotein enzymes that directly limit levels of ROS such as hydrogen peroxide (H2O2) or that reverse oxidative damage to ...
- Role of cytosolic phospholipase A(2)alpha in cell rounding and cytotoxicity induced by ceramide-1-phosphate via ceramide kinase
[作者:Nakamura, H; Tada, E; Makiyama, T; Yasufuku, K; Murayama, T,期刊:Archives of Biochemistry and Biophysics , 页码:45-51 , 文章类型: Article,,卷期:2011年512-1]
- Ceramide-1-phosphate (C1P), produced by ceramide kinase (CERK), is implicated in the regulation of many biological functions including cell growth and inflammation. C1P is a direct activator of group IVA cytosolic phosph...
- Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance
[作者:Sankala, H; Vaughan, C; Wang, J; Deb, S; Graves, PR,期刊:Archives of Biochemistry and Biophysics , 页码:52-60 , 文章类型: Article,,卷期:2011年512-1]
- The p53 gene is one of the most frequently mutated genes in human cancer. Some p53 mutations impart additional functions that promote oncogenesis. To investigate how these p53 mutants function, a proteomic analysis was p...
- Impact of inter-subunit interactions on the dimeric arginine kinase activity and structural stability
[作者:Wu, QY; Li, F; Wang, XY; Chen, ZJ,期刊:Archives of Biochemistry and Biophysics , 页码:61-68 , 文章类型: Article,,卷期:2011年512-1]
- Arginine kinase (AK) is a key enzyme for cellular energy metabolism, catalyzing the reversible phosphoryl transfer from phosphoarginine to ADP in invertebrates. In this study, the inter-subunit hydrogen bonds between the...
- Evidence for an inhibitory LIM domain in a rat brain agmatinase-like protein
[作者:Castro, V; Fuentealba, P; Henriquez, A; Vallejos, A; Benitez, J; Lobos, M; Diaz, B; Carvajal, N; Uribe, E,期刊:Archives of Biochemistry and Biophysics , 页码:107-110 , 文章类型: Article,,卷期:2011年512-1]
- We recently cloned a rat brain agmatinase-like protein (ALP) whose amino acid sequence greatly differs from other agmatinases and exhibits a LIM-like domain close to its carboxyl terminus. The protein was immunohistochem...
- Molecular diversity of the two sugar-binding sites of the beta-trefoil lectin HA33/C (HA1) from Clostridium botulinum type C neurotoxin
[作者:Nakamura, T; Tonozuka, T; Ito, S; Takeda, Y; Sato, R; Matsuo, I; Ito, Y; Oguma, K; Nishikawa, A,期刊:Archives of Biochemistry and Biophysics , 页码:69-77 , 文章类型: Article,,卷期:2011年512-1]
- A critical role in internalizing the Clostridium botulinum neurotoxin into gastrointestinal cells is played by nontoxic components complexed with the toxin. One of the components, a beta-trefoil lectin has been known as ...
- Interaction of aryl hydrocarbon receptor and NF-kappa B subunit RelB in breast cancer is associated with interleukin-8 overexpression
[作者:Vogel, CFA; Li, W; Wu, DL; Miller, JK; Sweeney, C; Lazennec, G; Fujisawa, Y; Matsumura, F,期刊:Archives of Biochemistry and Biophysics , 页码:78-86 , 文章类型: Article,,卷期:2011年512-1]
- The aryl hydrocarbon receptor (AhR) has been best known for its role in mediating the toxicity of dioxin. Here we show that AhR overexpression is found among estrogen receptor (ER)alpha-negative human breast tumors and t...
- Cellular magnesium homeostasis
[作者:Romani, AMP,期刊:Archives of Biochemistry and Biophysics , 页码:1-23 , 文章类型: Review,,卷期:2011年512-1]
- Magnesium, the second most abundant cellular cation after potassium, is essential to regulate numerous cellular functions and enzymes, including ion channels, metabolic cycles, and signaling pathways, as attested by more...
- Free [NADH]/[NAD(+)] regulates sirtuin expression
[作者:Gambini, J; Gomez-Cabrera, MC; Borras, C; Valles, SL; Lopez-Grueso, R; Martinez-Bello, VE; Herranz, D; Pallardo, FV; Tresguerres, JAF; Serrano, M; Vina, J,期刊:Archives of Biochemistry and Biophysics , 页码:24-29 , 文章类型: Article,,卷期:2011年512-1]
- Sirtuins are deacetylases involved in metabolic regulation and longevity. Our aim was to test the hypothesis that they are subjected to redox regulation by the [NADH]/[NAD(+)] ratio. We used NIH3T3 fibroblasts in culture...
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