- Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
[作者:Teta, M; Choi, YS; Okegbe, T; Wong, G; Tam, OH; Chong, MMW; Seykora, JT; Nagy, A; Littman, DR; Andl, T; Millar, SE,期刊:Development, 页码:1405-1416 , 文章类型: Article,,卷期:2012年139-8]
- MicroRNAs (miRNAs) regulate the expression of many mammalian genes and play key roles in embryonic hair follicle development; however, little is known of their functions in postnatal hair growth. We compared the effects ...
- Cell movements of the deep layer of non-neural ectoderm underlie complete neural tube closure in Xenopus
[作者:Morita, H; Kajiura-Kobayashi, H; Takagi, C; Yamamoto, TS; Nonaka, S; Ueno, N,期刊:Development, 页码:1417-1426 , 文章类型: Article,,卷期:2012年139-8]
- In developing vertebrates, the neural tube forms from a sheet of neural ectoderm by complex cell movements and morphogenesis. Convergent extension movements and the apical constriction along with apical-basal elongation ...
- The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and beta-cell differentiation
[作者:Metzger, DE; Gasperowicz, M; Otto, F; Cross, JC; Gradwohl, G; Zaret, KS,期刊:Development, 页码:1447-1456 , 文章类型: Article,,卷期:2012年139-8]
- Pancreatic beta-cells arise from Ngn3(+) endocrine progenitors within the trunk epithelium of the embryonic pancreas. The emergence of endocrine cells requires E-cadherin downregulation, but the crucial steps that elicit...
- Differential regulation of mesodermal gene expression by Drosophila cell type-specific Forkhead transcription factors
[作者:Zhu, XM; Ahmad, SM; Aboukhalil, A; Busser, BW; Kim, Y; Tansey, TR; Haimovich, A; Jeffries, N; Bulyk, ML; Michelson, AM,期刊:Development, 页码:1457-1466 , 文章类型: Article,,卷期:2012年139-8]
- A common theme in developmental biology is the repeated use of the same gene in diverse spatial and temporal domains, a process that generally involves transcriptional regulation mediated by multiple separate enhancers, ...
- A hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal differentiation and coordinates tissue maturation
[作者:Elkouby, YM; Polevoy, H; Gutkovich, YE; Michaelov, A; Frank, D,期刊:Development, 页码:1487-1497 , 文章类型: Article,,卷期:2012年139-8]
- During development, early inducing programs must later be counterbalanced for coordinated tissue maturation. In Xenopus laevis embryos, activation of the Meis3 transcription factor by a mesodermal Wnt3a signal lies at th...
- Context-dependent function of a conserved translational regulatory module
[作者:Liu, QW; Stumpf, C; Thomas, C; Wickens, M; Haag, ES,期刊:Development, 页码:1509-1521 , 文章类型: Article,,卷期:2012年139-8]
- The modification of transcriptional regulation is a well-documented evolutionary mechanism in both plants and animals, but post-transcriptional controls have received less attention. The derived hermaphrodite of C. elega...
- Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation
[作者:Chen, DM; Jarrell, A; Guo, CT; Lang, R; Atit, R,期刊:Development, 页码:1522-1533 , 文章类型: Article,,卷期:2012年139-8]
- Dermal fibroblasts are required for structural integrity of the skin and for hair follicle development. Uniform Wnt signaling activity is present in dermal fibroblast precursors preceding hair follicle initiation, but th...
- Diverse roles for VEGF-A in the nervous system
[作者:Mackenzie, F; Ruhrberg, C,期刊:Development, 页码:1371-1380 , 文章类型: Review,,卷期:2012年139-8]
- Vascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood vessel growth. However, evidence has emerged that VEGF-A also promotes a wide range of neuronal functions, both in vitro and in...
- Control of embryonic meristem initiation in Arabidopsis by PHD-finger protein complexes
[作者:Saiga, S; Moller, B; Watanabe-Taneda, A; Abe, M; Weijers, D; Komeda, Y,期刊:Development, 页码:1391-1398 , 文章类型: Article,,卷期:2012年139-8]
- Plant growth is directed by the activity of stem cells within meristems. The first meristems are established during early embryogenesis, and this process involves the specification of both stem cells and their organizer ...
|