- How to Remake a Fibroblast into a Neural Stem Cell
[作者：Zhou, Q; Tripathi, P,期刊：Cell Stem Cell, 页码：347-348 , 文章类型： Editorial Material，,卷期：2012年10-4]
- In this issue of Cell Stem Cell and in a recent issue of PNAS, Thier et al. (2012), Han et al. (2012), and Lujan et al. (2012) report the derivation of multipotent neural stem/progenitor cells from cultured mouse fibrobl...
- In Epigenetic Therapy, Less Is More
[作者：Shen, H; Laird, PW,期刊：Cell Stem Cell, 页码：353-354 , 文章类型： Editorial Material，,卷期：2012年10-4]
- How DNA methylation inhibitors exert their anticancer effects in patients is not well understood. In the latest issue of Cancer Cell, Tsai et al. (2012) use low-dose drug treatment to induce persistent attenuation of tum...
- The Stem Cell Niche in Regenerative Medicine
[作者：Wagers, AJ,期刊：Cell Stem Cell, 页码：362-369 , 文章类型： Article，,卷期：2012年10-4]
- Stem cells are fundamental units for achieving regenerative therapies, which leads naturally to a theoretical and experimental focus on these cells for therapeutic screening and intervention. A growing body of data in ma...
- Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells
[作者：Cheng, X; Ying, L; Lu, L; Galvao, AM; Mills, JA; Lin, HC; Kotton, DN; Shen, SS; Nostro, MC; Choi, JK; Weiss, MJ; French, DL; Gadue, P,期刊：Cell Stem Cell, 页码：371-384 , 文章类型： Article，,卷期：2012年10-4]
- The use of human pluripotent stem cells for laboratory studies and cell-based therapies is hampered by their tumor-forming potential and limited ability to generate pure populations of differentiated cell types in vitro....
- Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs
[作者：Mou, HM; Zhao, R; Sherwood, R; Ahfeldt, T; Lapey, A; Wain, J; Sicilian, L; Izvolsky, K; Musunuru, K; Cowan, C; Rajagopal, J,期刊：Cell Stem Cell, 页码：385-397 , 文章类型： Article，,卷期：2012年10-4]
- Deriving lung progenitors from patient-specific pluripotent cells is a key step in producing differentiated lung epithelium for disease modeling and transplantation. By mimicking the signaling events that occur during mo...
- Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells
[作者：Longmire, TA; Ikonomou, L; Hawkins, F; Christodoulou, C; Cao, YX; Jean, JC; Kwok, LW; Mou, HM; Rajagopal, J; Shen, SS; Dowton, AA; Serra, M; Weiss, DJ; Green, MD; Snoeck, HW; Ramirez, MI; Kotton, DN,期刊：Cell Stem Cell, 页码：398-411 , 文章类型： Article，,卷期：2012年10-4]
- Two populations of Nicx2-1+ progenitors in the developing foregut endoderm give rise to the entire postnatal lung and thyroid epithelium, but little is known about these cells because they are difficult to isolate in a p...
- Genetic and Pharmacologic Inhibition of beta-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML
[作者：Heidel, FH; Bullinger, L; Feng, ZH; Wang, Z; Neff, TA; Stein, L; Kalaitzidis, D; Lane, SW; Armstrong, SA,期刊：Cell Stem Cell, 页码：412-424 , 文章类型： Article，,卷期：2012年10-4]
- A key characteristic of hematopoietic stem cells (HSCs) is the ability to self-renew. Genetic deletion of beta-catenin during fetal HSC development leads to impairment of self-renewal while beta-catenin is dispensable in...
- Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors
[作者：Gillich, A; Bao, SQ; Grabole, N; Hayashi, K; Trotter, MWB; Pasque, V; Magnusdottir, E; Surani, MA,期刊：Cell Stem Cell, 页码：425-439 , 文章类型： Article，,卷期：2012年10-4]
- Epigenetic reprogramming in early germ cells is critical toward the establishment of totipotency, but investigations of the germline events are intractable. An objective cell culture-based system could provide mechanisti...
- Distinct Lineage Specification Roles for NANOG, OCT4, and SOX2 in Human Embryonic Stem Cells
[作者：Wang, Z; Oron, E; Nelson, B; Razis, S; Ivanova, N,期刊：Cell Stem Cell, 页码：440-454 , 文章类型： Article，,卷期：2012年10-4]
- Nanog, Oct4, and Sox2 are the core regulators of mouse (m)ESC pluripotency. Although their basic importance in human (h)ESCs has been demonstrated, the mechanistic functions are not well defined. Here, we identify genera...
- Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice
[作者：Ma, LX; Hu, BY; Liu, Y; Vermilyea, SC; Liu, HS; Gao, L; Sun, Y; Zhang, XQ; Zhang, SC,期刊：Cell Stem Cell, 页码：455-464 , 文章类型： Article，,卷期：2012年10-4]
- Degeneration of medium spiny GABA neurons in the basal ganglia underlies motor' dysfunction in Huntington's disease (HD), which presently lacks effective therapy. In this study, we have successfully directed human embryo...
- Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
[作者：Han, DW; Tapia, N; Hermann, A; Hemmer, K; Hoing, S; Arauzo-Bravo, MJ; Zaehres, H; Wu, GM; Frank, S; Moritz, S; Greber, B; Yang, JH; Lee, HT; Schwamborn, JC; Storch, A; Scholer, HR,期刊：Cell Stem Cell, 页码：465-472 , 文章类型： Article，,卷期：2012年10-4]
- Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell type without passing through a pluripotent state, but the restri...
- Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells
[作者：Thier, M; Worsdorfer, P; Lakes, YB; Gorris, R; Herms, S; Opitz, T; Seiferling, D; Quandel, T; Hoffmann, P; Nothen, MM; Brustle, O; Edenhofer, F,期刊：Cell Stem Cell, 页码：473-479 , 文章类型： Article，,卷期：2012年10-4]
- Recent advances have suggested that direct induction of neural stem cells (NSCs) could provide an alternative to derivation from somatic tissues or pluripotent cells. Here we show direct derivation of stably expandable N...
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