- Teicoplanin-loaded borate bioactive glass implants for treating chronic bone infection in a rabbit tibia osteomyelitis model
[作者:Zhang, X; Jia, WT; Gua, YF; Wei, XA; Liu, X; Wang, DP; Zhang, CQ; Huang, WH; Rahaman, MN; Day, DE; Zhou, N,期刊:BIOMATERIALS, 页码:5865-5874 , 文章类型: Article,,卷期:2010年31-22]
- The treatment of chronic osteomyelitis (bone infection) remains a clinical challenge. In this work, pellets composed of a chitosan-bonded mixture of borate bioactive glass particles (<50 mu m) and teicoplanin powder (ant...
- Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality
[作者:Martins, A; Duarte, ARC; Faria, S; Marques, AP; Reis, RL; Neves, NM,期刊:BIOMATERIALS, 页码:5875-5885 , 文章类型: Article,,卷期:2010年31-22]
- Electrospun structures were proposed as scaffolds owing to their morphological and structural similarities with the extracellular matrix found in many native tissues. These fibrous structures were also proposed as drug r...
- Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment
[作者:Kievit, FM; Florczyk, SJ; Leung, MC; Veiseh, O; Park, JO; Disis, ML; Zhang, MQ,期刊:BIOMATERIALS, 页码:5903-5910 , 文章类型: Article,,卷期:2010年31-22]
- Despite recent advances in the understanding of its cell biology, glioma remains highly lethal. Development of effective therapies requires a cost-effective in vitro tumor model that more accurately resembles the in vivo...
- Cell architecture-cell function dependencies on titanium arrays with regular geometry
[作者:Matschegewski, C; Staehlke, S; Loeffler, R; Lange, R; Chai, F; Kern, DP; Beck, U; Nebe, BJ,期刊:BIOMATERIALS, 页码:5729-5740 , 文章类型: Article,,卷期:2010年31-22]
- Knowledge about biocomplexity of cell behavior in dependence on topographical characteristics is of clinical relevance for the development of implant designs in tissue engineering. The aim of this study was to find out c...
- The influence of poly-N-[(2,2-dimethyl-1,3-dioxolane)methyl]acrylamide on fibrin polymerization, cross-linking and clot structure
[作者:Lai, BFL; Zou, YQ; Brooks, DE; Kizhakkedathu, JN,期刊:BIOMATERIALS, 页码:5749-5758 , 文章类型: Article,,卷期:2010年31-22]
- Poly-N-[(2,2-dimethyl-1,3-dioxolane)methyl]acrylamide (PDMDOMA) is a neutral synthetic water-soluble polymer. In this report, we evaluated the influence of PDMDOMA on blood hemostasis by studying the fibrin polymerizatio...
- Bradykinin forming capacity of oversulfated chondroitin sulfate contaminated heparin in vitro
[作者:Adam, A; Montpas, N; Keire, D; Desormeaux, A; Brown, NJ; Marceau, F; Westenberger, B,期刊:BIOMATERIALS, 页码:5741-5748 , 文章类型: Article,,卷期:2010年31-22]
- Oversulfated chondroitin sulfate (OSCS) contaminated heparin has been associated with severe anaphylactoid reaction (AR), mainly in dialysed patients. Although attributed to bradykinin (BK) released during contact system...
- Controlling dispersion of axonal regeneration using a multichannel collagen nerve conduit
[作者:Yao, L; de Ruiter, GCW; Wang, HA; Knight, AM; Spinner, RJ; Yaszemski, MJ; Windebank, AJ; Pandit, A,期刊:BIOMATERIALS, 页码:5789-5797 , 文章类型: Article,,卷期:2010年31-22]
- Single channel conduits are used clinically in nerve repair as an alternative to the autologous nerve graft. Axons regenerating across single channel tubes, however, may disperse resulting in inappropriate target reinner...
- The role of multiple toll-like receptor signalling cascades on interactions between biomedical polymers and dendritic cells
[作者:Shokouhi, B; Coban, C; Hasirci, V; Aydin, E; Dhanasingh, A; Shi, NA; Koyama, S; Akira, S; Zenke, M; Sechi, AS,期刊:BIOMATERIALS, 页码:5759-5771 , 文章类型: Article,,卷期:2010年31-22]
- Biomaterials are used in several health-related applications ranging from tissue regeneration to antigen-delivery systems. Yet, biomaterials often cause inflammatory reactions suggesting that they profoundly alter the ho...
- In vitro responses of human bone marrow stromal cells to a fluoridated hydroxyapatite coated biodegradable Mg-Zn alloy
[作者:Li, JN; Song, Y; Zhang, SX; Zhao, CL; Zhang, F; Zhang, XN; Cao, L; Fan, QM; Tang, TT,期刊:BIOMATERIALS, 页码:5782-5788 , 文章类型: Article,,卷期:2010年31-22]
- Bone-like fluoridated hydroxyapatite (FHA) coatings were prepared on Mg-6 wt.%Zn substrates using electrochemical method. Human bone marrow stromal cells (hBMSCs) were utilized to investigate the cellular biocompatibilit...
- The nanoscale properties of bacterial inclusion bodies and their effect on mammalian cell proliferation
[作者:Diez-Gil, C; Krabbenborg, S; Garcia-Fruitos, E; Vazquez, E; Rodriguez-Carmona, E; Ratera, I; Ventosa, N; Seras-Franzoso, J; Cano-Garrido, O; Ferrer-Miralles, N; Villaverde, A; Veciana, J,期刊:BIOMATERIALS, 页码:5805-5812 , 文章类型: Article,,卷期:2010年31-22]
- The chemical and mechanical properties of bacterial inclusion bodies, produced in different Escherichia coli genetic backgrounds, have been characterized at the nanoscale level. In regard to wild type, DnaK(-) and ClpA(-...
- Intervertebral disc regeneration after implantation of a cell-free bioresorbable implant in a rabbit disc degeneration model
[作者:Endres, M; Abbushi, A; Thomale, UW; Cabraja, M; Kroppenstedt, SN; Morawietz, L; Casalis, PA; Zenclussen, ML; Lemke, AJ; Horn, P; Kaps, C; Woiciechowsky, C,期刊:BIOMATERIALS, 页码:5836-5841 , 文章类型: Article,,卷期:2010年31-22]
- Degeneration of the intervertebral disc is the most common cause of lower back pain. Interestingly, all available treatments are limited to treat the symptoms and not the underlying biologic alterations of the disc. Free...
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