- Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles
[作者:Souris, JS; Lee, CH; Cheng, SH; Chen, CT; Yang, CS; Ho, JAA; Mou, CY; Lo, LW,期刊:BIOMATERIALS, 页码:5564-5574 , 文章类型: Article,,卷期:2010年31-21]
- Nanoparticle-assisted drug delivery has been emerging as an active research area in recent years. The in vivo biodistribution of nanoparticle and its following mechanisms of biodegradation and/or excretion determine the ...
- Induction and regulation of differentiation in neural stem cells on ultra-nanocrystalline diamond films
[作者:Chen, YC; Lee, DC; Tsai, TY; Hsiao, CY; Liu, JW; Kao, CY; Lin, HK; Chen, HC; Palathinkal, TJ; Pong, WF; Tai, NH; Lin, IN; Chiu, IM,期刊:BIOMATERIALS, 页码:5575-5587 , 文章类型: Article,,卷期:2010年31-21]
- The interaction of ultra-nanocrystalline diamond (UNCD) with neural stem cells (NSCs) has been studied in order to evaluate its potential as a biomaterial. Hydrogen-terminated UNCD (H-UNCD) films were compared with stand...
- The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer's disease
[作者:Spuch, C; Antequera, D; Portero, A; Drive, G; Hernandez, RM; Molina, JA; Bermejo-Pareja, F; Pedraz, JL; Carro, E,期刊:BIOMATERIALS, 页码:5608-5618 , 文章类型: Article,,卷期:2010年31-21]
- Cerebrovascular dysfunction contributes to cognitive decline and neurodegeneration in Alzheimer's disease (AD). Vascular endothelial growth factor (VEGF), an angiogenic protein with important neurotrophic and neuroprotec...
- The use of calcium phosphate nanoparticles encapsulating Toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activation
[作者:Sokolova, V; Knuschke, T; Kovtun, A; Buer, J; Epple, M; Westendorf, AM,期刊:BIOMATERIALS, 页码:5627-5633 , 文章类型: Article,,卷期:2010年31-21]
- Dendritic cells (DCs) are potent antigen-presenting cells that possess the ability to stimulate naive T cells. Antigen presentation by mature (activated) DCs is a prerequisite for the stimulation of antigen-specific T ce...
- EGFP-EGF1 protein-conjugated PEG-PLA nanoparticles for tissue factor targeted drug delivery
[作者:Mei, H; Shi, W; Pang, ZQ; Wang, HF; Lu, WY; Jiang, XG; Deng, J; Guo, T; Hu, Y,期刊:BIOMATERIALS, 页码:5619-5626 , 文章类型: Article,,卷期:2010年31-21]
- In a strategy for anti-thrombotic therapy, we have expressed EGFP-EGF1 fusion protein, in which EGF1 can bind with tissue factor (TF). EGFP has previously been widely used as a fluorescent protein marker. EGFP-EGF1 prote...
- Co-delivery of PDTC and doxorubicin by multifunctional micellar nanoparticles to achieve active targeted drug delivery and overcome multidrug resistance
[作者:Fan, L; Li, F; Zhang, HT; Wang, YK; Cheng, C; Li, XY; Gu, CH; Yang, QA; Wu, H; Zhang, SY,期刊:BIOMATERIALS, 页码:5634-5642 , 文章类型: Article,,卷期:2010年31-21]
- Micellar nanoparticles self-assembled from copolymer folate chitosan (FA CS) were employed as carriers to co-deliver Pyrrolidinedithiocarbamate (PDTC) and doxorubicin (DOX) to achieve targeted DOX delivery, with a pH res...
- The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers
[作者:Liu, JY; Huang, W; Pang, Y; Zhu, XY; Zhou, YF; Yan, DY,期刊:BIOMATERIALS, 页码:5643-5651 , 文章类型: Article,,卷期:2010年31-21]
- Polymeric micelles are recognized as very promising nanocarriers for small-molecule drugs. DNA, and proteins delivery. Polyphosphates are an important class of eminent biomaterials and widely used in biomedicine due to t...
- Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells
[作者:Lee, SJ; Kang, SW; Do, HJ; Han, I; Shin, DA; Kim, JH; Lee, SH,期刊:BIOMATERIALS, 页码:5652-5659 , 文章类型: Article,,卷期:2010年31-21]
- Adipose tissue contains multipotent mesenchymal stem cells (MSCs) that are able to differentiate into various tissues. Bone morphogenetic protein 2 (BMP2) is known as one of the key osteogenesis induction factors in MSCs...
- Effects of the nanostructure of dendrimer/DNA complexes on their endocytosis and gene expression
[作者:Peng, SF; Su, CJ; Wei, MC; Chen, CY; Liao, ZX; Lee, PW; Chen, HL; Sung, HW,期刊:BIOMATERIALS, 页码:5660-5670 , 文章类型: Article,,卷期:2010年31-21]
- Cationic dendrimers constitute a potential nonviral vector for gene therapy due to their ability of forming electrostatic complexes with DNA (dendriplexes). However, the supramolecular structure of dendriplexes and its i...
- Surface functionalisation of PLGA nanoparticles for gene silencing
[作者:Andersen, MO; Lichawska, A; Arpanaei, A; Jensen, SMR; Kaur, H; Oupicky, D; Besenbacher, F; Kingshott, P; Kjems, J; Howard, KA,期刊:BIOMATERIALS, 页码:5671-5677 , 文章类型: Article,,卷期:2010年31-21]
- This work presents a method for decorating the surface of poly (lactide-co-glycolide) (PLGA) nanoparticles with polyethyleneimine (PEI) utilising a cetyl derivative to improve surface functionalisation and siRNA delivery...
- The effect of bovine endosteum-derived particles on the proliferation of human mesenchymal stem cells
[作者:Nigro, J; White, JF; Ramshaw, JAM; Haylock, DN; Nilsson, SK; Werkmeister, JA,期刊:BIOMATERIALS, 页码:5689-5699 , 文章类型: Article,,卷期:2010年31-21]
- There is a large biomanufacturing and clinical need for cost-effective and simple techniques to expand mesenchymal stem cells whilst retaining their multipotency. Endosteum-derived particles were prepared, characterised ...
- Multilayer microfluidic PEGDA hydrogels
[作者:Cuchiara, MP; Allen, ACB; Chen, TM; Miller, JS; West, JL,期刊:BIOMATERIALS, 页码:5491-5497 , 文章类型: Article,,卷期:2010年31-21]
- Development of robust 3D tissue analogs in vitro is limited by passive. diffusional mass transport. Perfused microfluidic tissue engineering scaffolds hold the promise to improve mass transport limitations and promote th...
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