- Glucocorticosteroids Increase Cell Entry by Hepatitis C Virus
[作者：Ciesek, S; Steinmann, E; Iken, M; Ott, M; Helfritz, FA; Wappler, I; Manns, MP; Wedemeyer, H; Pietschmann, T,期刊：Gastroenterology, 页码：1875-1884 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Corticosteroids are used as immunosuppressants in patients with autoimmune disorders and transplant recipients. However, these drugs worsen hepatitis C virus (HCV) recurrence after liver transplantatio...
- Inflammatory Bowel Disease Confers a Lower Risk of Colorectal Cancer to Females Than to Males
[作者：Soderlund, S; Granath, F; Brostrom, O; Karlen, P; Lofberg, R; Ekbom, A; Askling, J,期刊：Gastroenterology, 页码：1697-U6 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Reported differences in cancer risk between male and female animals after chronic inflammation suggest that estrogen has inflammation-modifying properties. Little is known about these effects in human ...
- Interferon-alpha-Induced TRAIL on Natural Killer Cells Is Associated With Control of Hepatitis C Virus Infection
[作者：Stegmann, KA; Bjorkstrom, NK; Veber, H; Ciesek, S; Riese, P; Wiegand, J; Hadem, J; Suneetha, PV; Jaroszewicz, J; Wang, C; Schlaphoff, V; Fytili, P; Cornberg, M; Manns, MP; Geffers, R; Pietschmann, T; Guzman, CA; Ljunggren, HG; Wedemeyer, H,期刊：Gastroenterology, 页码：1885-U68 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Pegylated interferon-alpha (PEG-IFN alpha), in combination with ribavirin, controls hepatitis C virus (HCV) infection in approximately SO% of patients by mechanisms that are not completely understood. ...
- Functional Switching of TGF-beta 1 Signaling in Liver Cancer via Epigenetic Modulation of a Single CpG Site in TTP Promoter
[作者：Sohn, BH; Park, IY; Lee, JJ; Yang, SJ; Jang, YJ; Park, KC; Kim, DJ; Lee, DC; Sohn, HA; Kim, TW; Yoo, HS; Choi, JY; Bae, YS; Yeom, YI,期刊：Gastroenterology, 页码：1898-U80 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Acquisition of resistance to the antiproliferative effect of transforming growth factor (TGF)beta 1 is crucial for the malignant progression of cancers. In this study, we sought to determine whether de...
- Selenium Status and the Risk of Esophageal and Gastric Cancer Subtypes: The Netherlands Cohort Study
[作者：Steevens, J; van den Brandt, PA; Goldbohm, RA; Schouten, LJ,期刊：Gastroenterology, 页码：1704-1713 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Selenium may protect against the development of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), and gastric cardia adenocarcinoma (GCA). Only in very few studies have the as...
- Meta-analysis Shows That Detection of Circulating Tumor Cells Indicates Poor Prognosis in Patients With Colorectal Cancer
[作者：Rahbari, NN; Aigner, M; Thorlund, K; Mollberg, N; Motschall, E; Jensen, K; Diener, MK; Buchler, MW; Koch, M; Weitz, J,期刊：Gastroenterology, 页码：1714-U20 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: The prognostic significance of circulating (CTCs) and disseminated tumor cells in patients with colorectal cancer (CRC) is controversial. We performed a meta-analysis of available studies to assess whe...
- Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells
[作者：Rivadeneira, DB; Mayhew, CN; Thangavel, C; Sotillo, E; Reed, CA; Grana, X; Knudsen, ES,期刊：Gastroenterology, 页码：1920-U92 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Hepatocellular carcinoma is the third leading cause of cancer mortality worldwide; current chemotherapeutic interventions for this disease are largely ineffective. The retinoblastoma tumor suppressor (...
- Radiofrequency Thermal Ablation for Hepatocellular Carcinoma Stimulates Autologous NK-Cell Response
[作者：Zerbini, A; Pilli, M; Laccabue, D; Pelosi, G; Molinari, A; Negri, E; Cerioni, S; Fagnoni, F; Soliani, P; Ferrari, C; Missale, G,期刊：Gastroenterology, 页码：1931-U94 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Radiofrequency thermal ablation (RFA) is a minimally invasive technique used as standard local therapy of hepatocellular carcinoma and second-line treatment for metastatic liver tumors. Studies in prec...
- HuR/Methyl-HuR and AUF1 Regulate the MAT Expressed During Liver Proliferation, Differentiation, and Carcinogenesis
[作者：Vazquez-Chantada, M; Fernandez-Ramos, D; Embade, N; Martinez-Lopez, N; Varela-Rey, M; Woodhoo, A; Luka, Z; Wagner, C; Anglim, PP; Finnell, RH; Caballeria, J; Laird-Offringa, IA; Gorospe, M; Lu, SC; Mato, JM; Martinez-Chantar, ML,期刊：Gastroenterology, 页码：1943-U97 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Hepatic de-differentiation, liver development, and malignant transformation are processes in which the levels of hepatic S-adenosylmethionine are tightly regulated by 2 genes: methionine adenosyltransf...
- alpha Cell-Specific Men1 Ablation Triggers the Transdifferentiation of Glucagon-Expressing Cells and Insulinoma Development
[作者：Lu, JL; Herrera, PL; Carreira, C; Bonnavion, R; Seigne, C; Calender, A; Bertolino, P; Zhang, CX,期刊：Gastroenterology, 页码：1954-U105 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: The tumor suppressor menin is recognized as a key regulator of pancreatic islet development, proliferation, and beta-cell function, whereas its role in alpha cells remains poorly understood. The purpos...
- Glucose-Dependent Insulinotropic Polypeptide Is Expressed in Pancreatic Islet alpha-Cells and Promotes Insulin Secretion
[作者：Fujita, Y; Wideman, RD; Asadi, A; Yang, GK; Baker, R; Webber, T; Zhang, TJ; Wang, RN; Ao, ZL; Warnock, GL; Kwok, YN; Kieffer, TJ,期刊：Gastroenterology, 页码：1966-U106 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Glucose-dependent insulinotropic polypeptide (GIP) and the proglucagon product glucagon-like peptide-1 (GLP-1) are gastrointestinal hormones that are released in response to nutrient intake and promote...
- Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells
[作者：Voronina, SG; Barrow, SL; Simpson, AWM; Gerasimenko, OV; Xavier, GD; Rutter, GA; Petersen, OH; Tepikin, AV,期刊：Gastroenterology, 页码：1976-U111 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Previous studies of pancreatic acinar cells characterized the effects of Ca(2+-)releasing secretagogues and substances, inducing acute pancreatitis on mitochondrial Ca2+, transmembrane potential, and N...
- Corticosteroids Correct Aberrant CFTR Localization in the Duct and Regenerate Acinar Cells in Autoimmune Pancreatitis
[作者：Ko, SBH; Mizuno, N; Yatabe, Y; Yoshikawa, T; Ishiguro, H; Yamamoto, A; Azuma, S; Naruse, S; Yamao, K; Muallem, S; Goto, H,期刊：Gastroenterology, 页码：1988-U114 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Corticosteroids are now widely accepted as a treatment for autoimmune pancreatitis (AIP). However, the molecular mechanism by which steroid treatment improves AIP remains largely unknown. The aim of th...
- Cholecystokinin Knockout Mice Are Resistant to High-Fat Diet-Induced Obesity
[作者：Lo, CM; King, A; Samuelson, LC; Kindel, TL; Rider, T; Jandacek, RJ; Raybould, HE; Woods, SC; Tso, P,期刊：Gastroenterology, 页码：1997-2005 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Cholecystokinin (CCK) is a satiation peptide released during meals in response to lipid intake; it regulates pancreatic digestive enzymes that are required for absorption of nutrients. We proposed that...
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