- Hepatitis C Virus Infection Reduces Hepatocellular Polarity in a Vascular Endothelial Growth Factor-Dependent Manner
[作者:Mee, CJ; Farquhar, MJ; Harris, HJ; Hu, K; Ramma, W; Ahmed, A; Maurel, P; Bicknell, R; Balfe, P; McKeating, JA,期刊:Gastroenterology, 页码:1134-1142 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease, frequently culminating in fibrosis and hepatocellular carcinoma. The mechanisms underlying liver injury in chronic hepatitis C are ...
- History, Molecular Mechanisms, and Endoscopic Treatment of Barrett's Esophagus
[作者:Spechler, SJ; Fitzgerald, RC; Prasad, GA; Wang, KK,期刊:Gastroenterology, 页码:854-869 , 文章类型: Review,,卷期:2010年138-3]
- This report is an adjunct to the American Gastroenterological Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future. ...
- Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro
[作者:Roig, AI; Eskiocak, U; Hight, SK; Kim, SB; Delgado, O; Souza, RF; Spechler, SJ; Wright, WE; Shay, JW,期刊:Gastroenterology, 页码:1012-U272 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: Long-term propagation of human colonic epithelial cells (HCEC) of adult origin has been a challenge; currently used HCEC lines are of malignant origin and/or contain multiple cytogenetic changes. We so...
- Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer
[作者:Zhang, L; Farrell, JJ; Zhou, H; Elashoff, D; Akin, D; Park, NH; Chia, D; Wong, DT,期刊:Gastroenterology, 页码:949-U194 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: Lack of detection technology for early pancreatic cancer invariably leads to a typical clinical presentation of incurable disease at initial diagnosis. New strategies and biomarkers for early detection...
- Secretory Cell Hyperplasia and Defects in Notch Activity in a Mouse Model of Leukocyte Adhesion Deficiency Type II
[作者:Waterhouse, CCM; Johnson, S; Phillipson, M; Zbytnuik, L; Petri, B; Kelly, M; Lowe, JB; Kubes, P,期刊:Gastroenterology, 页码:1079-U364 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: Leukocyte adhesion deficiency II (LAD II) is a rare condition caused by defective protein fucosylation, causing decreased leukocyte rolling, psychomotor retardation, and poor growth. The ligand-binding...
- Sensory and Motor Innervation of the Crural Diaphragm by the Vagus Nerves
[作者:Young, RL; Page, AJ; Cooper, NJ; Frisby, CL; Blackshaw, LA,期刊:Gastroenterology, 页码:1091-U380 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: During gastroesophageal reflux, transient lower esophageal sphincter relaxation and crural diaphragm (CD) inhibition occur concomitantly. Modifying vagus nerve control of transient lower esophageal sph...
- Stat3 Is a Negative Regulator of Intestinal Tumor Progression in Apc(Min) Mice
[作者:Musteanu, M; Blaas, L; Mair, M; Schlederer, M; Bilban, M; Tauber, S; Esterbauer, H; Mueller, M; Casanova, E; Kenner, L; Poli, V; Eferl, R,期刊:Gastroenterology, 页码:1003-U257 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND AND AIMS: The transcription factor signal transducer and activator of transcription 3 (Stat3) has been considered to promote progression and metastasis of intestinal cancers. METHODS: We investigated the role ...
- Population-Based Family History-Specific Risks for Colorectal Cancer: A Constellation Approach
[作者:Taylor, DP; Burt, RW; Williams, MS; Haug, PJ; Cannon-Albright, LA,期刊:Gastroenterology, 页码:877-885 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: Colorectal cancer (CRC) risk estimates based on family history typically include only close relatives. We report familial relative risk (FRR) in probands with various combinations, or constellations, o...
- Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model
[作者:Laroui, H; Dalmasso, G; Nguyen, HTT; Yan, YT; Sitaraman, SV; Merlin, D,期刊:Gastroenterology, 页码:843-U77 , 文章类型: Article,,卷期:2010年138-3]
- BACKGROUND & AIMS: One of the challenges to treating inflammatory bowel disease (IBD) is to target the site of inflammation. We engineered nanoparticles (NPs) to deliver an anti-inflammatory tripeptide Lys-Pro-Val (KPV) ...
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