- HDL as a Biomarker, Potential Therapeutic Target, and Therapy
[作者：Navab, M; Anantharamaiah, GM; Reddy, ST; Van Lenten, BJ; Al Fogelman, A,期刊：Diabetes, 页码：2711-2717 , 文章类型： Article，,卷期：2009年58-12]
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- Distinct Effects of Leptin and a Melanocortin Receptor Agonist Injected Into Medial Hypothalamic Nuclei on Glucose Uptake in Peripheral Tissues
[作者：Toda, C; Shiuchi, T; Lee, S; Yamato-Esaki, M; Fujino, Y; Suzuki, A; Okamoto, S; Minokoshi, Y,期刊：Diabetes, 页码：2757-2765 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-The medial hypothalamus mediates leptin-induced glucose uptake in peripheral tissues, mid brain melanocortin receptors (MCRs) mediate certain central effects of leptin. However, the contributions of the leptin ...
- Impact of 9 Days of Bed Rest on Hepatic and Peripheral Insulin Action, Insulin Secretion, and Whole-Body Lipolysis in Healthy Young Male Offspring of Patients With Type 2 Diabetes
[作者：Alibegovic, AC; Hojbjerre, L; Sonne, MP; van Hall, G; Stallknecht, B; Dela, F; Vaag, A,期刊：Diabetes, 页码：2749-2756 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-The aim of this study was to investigate the impact of 9 days of bed rest on insulin secretion, insulin action, and whole-body glucose and fat metabolism in first-degree relative (FDR) and matched control (CON)...
- Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice
[作者：Li, JH; Gautam, D; Han, SJ; Guettier, JM; Cui, YH; Lu, HY; Deng, CX; O'Hare, J; Jou, W; Gavrilova, O; Buettner, C; Wess, J,期刊：Diabetes, 页码：2776-2787 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-An increase in the rate of hepatic glucose production is the major determinant of fasting hyperglycemia in type 2 diabetes. A better understanding of the signaling pathways and molecules that regulate hepatic g...
- Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis In Vivo
[作者：Edgerton, DS; Ramnanan, CJ; Grueter, CA; Johnson, KMS; Lautz, M; Neal, DW; Williams, PE; Cherrington, AD,期刊：Diabetes, 页码：2766-2775 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-Insulin represses the expression of gluconeogenic genes at the mRNA level, but the hormone appears to have only weak inhibitory effects in vivo. The aims of this study were 1) to determine the maximal physiolog...
- Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia
[作者：Hojman, P; Pedersen, M; Nielsen, AR; Krogh-Madsen, R; Yfanti, C; Akerstrom, T; Nielsen, S; Pedersen, BK,期刊：Diabetes, 页码：2797-2801 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-Fibroblast growth factor-21 (FGF-21) is a potent metabolic regulator, which in animal models has been shown to improve glucose metabolism and insulin sensitivity. Recently, FGF-21 was shown to be expressed and ...
- Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77
[作者：Chao, LC; Wroblewski, K; Zhang, ZD; Pei, LM; Vergnes, L; Ilkayeva, OR; Ding, SY; Reue, K; Watt, MJ; Newgard, CB; Pilch, PF; Hevener, AL; Tontonoz, P,期刊：Diabetes, 页码：2788-2796 , 文章类型： Proceedings Paper，,卷期：2009年58-12]
- OBJECTIVE-Nur77 is an orphan nuclear receptor with pleotropic functions. Previous studies have identified Nur77 as a transcriptional regulator of glucose utilization genes in skeletal muscle and gluconeogenesis in liver....
- Glucose Deprivation Regulates K-ATP Channel Trafficking via, AMP-Activated Protein Kinase in Pancreatic beta-Cells
[作者：Lim, A; Park, SH; Sohn, JW; Jeon, JH; Park, JH; Song, DK; Lee, SH; Ho, WK,期刊：Diabetes, 页码：2813-2819 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-AMP-activated protein kinase (AMPK) and the ATP-sensitive K+ (K-ATP) channel are metabolic sensors that become activated during metabolic stress. AMPK is an important regulator of metabolism, whereas the K-ATP ...
- Functional Role of Neuroendocrine-Specific Protein-Like 1 in Membrane Translocation of GLUT4
[作者：Ikemoto, T; Hosoya, T; Takata, K; Aoyama, H; Hiramatsu, T; Onoe, H; Suzuki, M; Endo, M,期刊：Diabetes, 页码：2802-2812 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-In skeletal muscles, dantrolene inhibits the exercise-induced membrane translocation of GLUT4. It has been postulated that the inhibitory action of dantrolene on Ca2+ release from the sarcoplasmic reticulum (SR...
- SIRT1 Genetic Variation Is Related to BMI and Risk of Obesity
[作者：Zillikens, MC; van Meurs, JBJ; Rivadeneira, F; Amin, N; Hofman, A; Oostra, BA; Sijbrands, EJG; Wittentan, JCM; Pols, HAP; van Duijn, CM; Uitterlinden, AG,期刊：Diabetes, 页码：2828-2834 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-SIRT1 has pleiotropic metabolic functions. We investigated whether SIRT1 genetic variation is associated with obesity. RESEARCH DESIGN AND METHODS-In 6,251 elderly subjects from the prospective, population-base...
- Differences in the Central Anorectic Effects of Glucagon-Like Peptide-1 and Exendin-4 in Rats
[作者：Barrera, JG; D'Alessio, DA; Drucker, DJ; Woods, SC; Seeley, RJ,期刊：Diabetes, 页码：2820-2827 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-Glucagon-like peptide (GLP)-1 is a regulatory peptide synthesized in the gut and the brain that plays an important role in the regulation of food intake. Both GLP-1 and exendin (Ex)-4, a long-acting GLP-1 recep...
- Predictive Characteristics of Diabetes-Associated Autoantibodies Among Children With HLA-Conferred Disease Susceptibility in the General Population
[作者：Siljander, HTA; Simell, S; Hekkala, A; Lahde, J; Simell, T; Vahasalo, P; Veijola, R; Ilonen, J; Simell, O; Knip, M,期刊：Diabetes, 页码：2835-2842 , 文章类型： Article，,卷期：2009年58-12]
- OBJECTIVE-As data on the predictive characteristics of diabetes-associated autoantibodies for type 1 diabetes in the general population are scarce, we assessed the predictive performance of islet cell autoantibodies (ICA...
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