- Clinical Evaluation of Safety and Immunogenicity of PADRE-Cytomegalovirus (CMV) and Tetanus-CMV Fusion Peptide Vaccines With or Without PF03512676 Adjuvant
[作者:La Rosa, C; Longmate, J; Lacey, SF; Kaltcheva, T; Sharan, R; Marsano, D; Kwon, P; Drake, J; Williams, B; Denison, S; Broyer, S; Couture, L; Nakamura, R; Kelsey, MI; Krieg, AM; Diamond, DJ; Zaia, JA,期刊:Journal of Infectious Diseases, 页码:1294-1304 , 文章类型: Article,,卷期:2012年205-8]
- Background. It has been reported that cytomegalovirus (CMV) pp65-specific T cells can protect hematopoietic cell transplant (HCT) recipients from CMV complications. Two candidate CMV peptide vaccines composed of the HLA ...
- Cytomegalovirus Infection During Pregnancy With Maternofetal Transmission Induces a Proinflammatory Cytokine Bias in Placenta and Amniotic Fluid
[作者:Scott, GM; Chow, SSW; Craig, ME; Pang, CNI; Hall, B; Wilkins, MR; Jones, CA; Lloyd, AR; Rawlinson, WD,期刊:Journal of Infectious Diseases, 页码:1305-1310 , 文章类型: Article,,卷期:2012年205-8]
- Congenital infection with cytomegalovirus (CMV) can induce immune responses and placental damage. By use of immunoassay panels, 27 cytokines were assessed in midtrimester amniotic fluid from 8 patients with congenital CM...
- Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
[作者:da Cruz, FP; Martin, C; Buchholz, K; Lafuente-Monasterio, MJ; Rodrigues, T; Sonnichsen, B; Moreira, R; Gamo, FJ; Marti, M; Mota, MM; Hannus, M; Prudencio, M,期刊:Journal of Infectious Diseases, 页码:1278-1286 , 文章类型: Article,,卷期:2012年205-8]
- Plasmodium parasites undergo a clinically silent and obligatory developmental phase in the host's liver cells before they are able to infect erythrocytes and cause malaria symptoms. To overcome the scarcity of compounds ...
- Magnitude of Virologic Blips Is Associated With a Higher Risk for Virologic Rebound in HIV-Infected Individuals: A Recurrent Events Analysis
[作者:Grennan, JT; Loutfy, MR; Su, DS; Harrigan, PR; Cooper, C; Klein, M; Machouf, N; Montaner, JSG; Rourke, S; Tsoukas, C; Hogg, B; Raboud, J,期刊:Journal of Infectious Diseases, 页码:1230-1238 , 文章类型: Article,,卷期:2012年205-8]
- Background. The importance of human immunodeficiency virus (HIV) blip magnitude on virologic rebound has been raised in clinical guidelines relating to viral load assays. Methods. Antiretroviral-naive individuals initiat...
- Male Human Papillomavirus Prevalence and Association With Condom Use in Brazil, Mexico, and the United States
[作者:Repp, KK; Nielson, CM; Fu, RW; Schafer, S; Lazcano-Ponce, E; Salmeron, J; Quiterio, M; Villa, LL; Giuliano, AR,期刊:Journal of Infectious Diseases, 页码:1287-1293 , 文章类型: Article,,卷期:2012年205-8]
- Background. Reported associations of condom use and human papillomavirus (HPV) infection have been inconsistent. We investigated self-reported frequency of condom use and detection of genital HPV among men. Methods. A cr...
- Murine Infection Models for Aspergillus terreus Pulmonary Aspergillosis Reveal Long-term Persistence of Conidia and Liver Degeneration
[作者:Slesiona, S; Ibrahim-Granet, O; Olias, P; Brock, M; Jacobsen, ID,期刊:Journal of Infectious Diseases, 页码:1268-1277 , 文章类型: Article,,卷期:2012年205-8]
- Aspergillus terreus is emerging as a causative agent of life-threatening invasive aspergillosis. Prognosis for affected patients is often worse than for A. fumigatus infections. To study A. terreus-mediated disease, we d...
- The Mycobacterium tuberculosis Stress Response Factor SigH Is Required for Bacterial Burden as Well as Immunopathology in Primate Lungs
[作者:Mehra, S; Golden, NA; Stuckey, K; Didier, PJ; Doyle, LA; Russell-Lodrigue, KE; Sugimoto, C; Hasegawa, A; Sivasubramani, SK; Roy, CJ; Alvarez, X; Kuroda, MJ; Blanchard, JL; Lackner, AA; Kaushal, D,期刊:Journal of Infectious Diseases, 页码:1203-1213 , 文章类型: Article,,卷期:2012年205-8]
- Background. Sigma H (sigH) is a major Mycobacterium tuberculosis (Mtb) stress response factor. It is induced in response to heat, oxidative stress, cell wall damage, and hypoxia. Infection of macrophages with the delta-s...
- Newly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008-2010
[作者:Octavia, S; Sintchenko, V; Gilbert, GL; Lawrence, A; Keil, AD; Hogg, G; Lan, RT,期刊:Journal of Infectious Diseases, 页码:1220-1224 , 文章类型: Article,,卷期:2012年205-8]
- Australia is experiencing a prolonged epidemic of pertussis that began in 2008. A total of 194 Bordetella pertussis isolates collected from 2008 through 2010 were typed by single-nucleotide polymorphism (SNP) analysis, b...
- Gene Polymorphism in Toll-like Receptor 4: Effect on Antibody Production and Persistence After Acellular Pertussis Vaccination During Adolescence
[作者:Grondahl-Yli-Hannuksela, K; Vuononvirta, J; Barkoff, AM; Viander, M; Van der Meeren, O; Mertsola, J; He, QS,期刊:Journal of Infectious Diseases, 页码:1214-1219 , 文章类型: Article,,卷期:2012年205-8]
- Background. Toll-like receptors play an important role in the regulation of adaptive immunity. This study aimed to investigate whether Toll-like receptor 4 (TLR4) polymorphisms influence the production and persistence of...
- Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection
[作者:Miller, AL; Sims, GP; Brewah, YA; Rebelatto, MC; Kearley, J; Benjamin, E; Keller, AE; Brohawn, P; Herbst, R; Coyle, AJ; Humbles, AA; Kolbeck, R,期刊:Journal of Infectious Diseases, 页码:1311-1320 , 文章类型: Article,,卷期:2012年205-8]
- Respiratory syncytial virus (RSV), a common respiratory pathogen in infants and the older population, causes pulmonary inflammation and airway occlusion that leads to impairment of lung function. Here, we have establishe...
- Transmembrane Domain Membrane Proximal External Region but Not Surface Unit-Directed Broadly Neutralizing HIV-1 Antibodies Can Restrict Dendritic Cell-Mediated HIV-1 Trans-infection
[作者:Sagar, M; Akiyama, H; Etemad, B; Ramirez, N; Freitas, I; Gummuluru, S,期刊:Journal of Infectious Diseases, 页码:1248-1257 , 文章类型: Article,,卷期:2012年205-8]
- Background. Although broadly neutralizing antibodies (bNAbs) have been shown to block a diverse array of cell-free human immunodeficiency type 1 (HIV-1) infections, it remains unclear whether these antibodies exhibit sim...
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