- Bortezomib Therapeutic Effect is Associated with Expression of FGFR3 in Multiple Myeloma Cells
[作者:Guan, M; Zhu, LJ; Somlo, G; Hughes, A; Zhou, BS; Yen, Y,期刊:Anticancer Research, 页码:1-9 , 文章类型: Article,,卷期:2009年29-1]
- The ectopically expressed and deregulated fibroblast growth factor receptor 3 (FGFR3) has been observed in similar to 20% of multiple myeloma (MM) patients. In this study, we investigated whether the therapeutic effect o...
- Gene Amplification of Myc and its Coamplification with ERBB2 and EGFR in Gallbladder Adenocarcinoma
[作者:Ooi, A; Suzuki, S; Nakazawa, K; Itakura, J; Imoto, I; Nakamura, H; Dobashi, Y,期刊:Anticancer Research, 页码:19-26 , 文章类型: Article,,卷期:2009年29-1]
- Background: Among the combinations coamplified genes, Myc and ERBB2 or EGFR have attracted much attention for their relevance to cytogenetics, carcinogenesis and cancer therapy. Materials and Methods: Gene amplification ...
- Effect of Verapamil on the Expression of EGFR and NM23 in A549 Human Lung Cancer Cells
[作者:Zhang, CD; Lv, FZ; Zhou, L; Li, XY; Wu, XX; Hoffman, RM,期刊:Anticancer Research, 页码:27-32 , 文章类型: Article,,卷期:2009年29-1]
- Despite the advances in the detection and treatment of lung cancer, the overall 5-year survival is only 10-20%. Accumulating evidence suggests that verapamil, a calcium channel antagonist, is a potential anticancer agent...
- Distinct Patient Responses to Activation of T-cells by Free HER-2, G89 (777-789) and Protected LRMK-linked HER-2, {AE-39 [p776 (Ava-774-788)], AE-47 [(Ava-776-788)] and AE-37[p776 (774-788)]} Peptides Could Lead to Development of Personalized Cancer Vaccines
[作者:Li, YF; Matsueda, S; Efferson, CL; Tsuda, N; Kawano, K; Gao, H; Peoples, GE; Ioannides, CG,期刊:Anticancer Research, 页码:41-58 , 文章类型: Article,,卷期:2009年29-1]
- The objective of this study was to find whether the peptide LRMK linked to the N-terminus of HER-2, 774-788 and shorter peptides create a T helper antigen, which can replace all functional HER-2 peptides in a cancer vacc...
- Differences in the Gene Expression Profile of Matrix Metalloproteinases (MMPs) and their Inhibitors (TIMPs) in Primary Colorectal Tumors and their Synchronous Liver Metastases
[作者:Gentner, B; Wein, A; Croner, RS; Zeittraeger, I; Wirtz, RM; Roedel, F; Dimmler, A; Dorlaque, L; Hohenberger, W; Hahn, EG; Brueckl, WM,期刊:Anticancer Research, 页码:67-74 , 文章类型: Article,,卷期:2009年29-1]
- Background: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) have been strongly implicated in the pathogenesis of many types of human cancer. We wanted to specifically define their role in established...
- Changes in Plasma TIMP-1 Levels after Resection for Primary Colorectal Cancer
[作者:Frederiksen, C; Lomholt, AF; Davis, GJ; Dowell, BL; Blankenstein, MA; Christensen, IJ; Brunner, N; Nielsen, HJ,期刊:Anticancer Research, 页码:75-81 , 文章类型: Article,,卷期:2009年29-1]
- Background: Increased plasma levels of tissue inhibitor of metalloproteinases (TIMP-1) are associated with poor outcome in colorectal cancer (CRC), however postoperative changes in plasma TIMP-1 levels after resections f...
- Utilization of a Right-handed Coiled-coil Protein from Archaebacterium Staphylothermus marinus as a Carrier for Cisplatin
[作者:Eriksson, M; Hassan, S; Larsson, R; Linder, S; Ramqvist, T; Lovborg, H; Vikinge, T; Figgemeier, E; Muller, J; Stetefeld, J; Dalianis, T; Ozbek, S,期刊:Anticancer Research, 页码:11-18 , 文章类型: Article,,卷期:2009年29-1]
- Background: The nano-sized right-handed coiled-coil (RHCC) protein, originating front the archaebacterium Staphylothermus marinus, is stable at high salt concentrations, high temperatures, high pressures and extremes of ...
- DNA Image Cytometry Predicts Disease Outcome in Stage II Colorectal Carcinoma
[作者:Buhmeida, A; Hilska, M; Elzagheid, A; Laato, M; Collan, Y; Syrjanen, K; Pyrhonen, S,期刊:Anticancer Research, 页码:99-106 , 文章类型: Article,,卷期:2009年29-1]
- Background: Approximately 30% of all colorectal cancer (CRC) patients are diagnosed with stage H disease. Adjuvant therapy is not widely recommended. However, it is well established that a subgroup of patients with stage...
- Antioxidant Effects of Quercetin and Coenzyme Q10 in Mini Organ Cultures of Human Nasal Mucosa Cells
[作者:Reiter, M; Rupp, K; Baumeister, P; Zieger, S; Harreus, U,期刊:Anticancer Research, 页码:33-39 , 文章类型: Article,,卷期:2009年29-1]
- Background: Oxidative DNA damage is a known risk factor of head and neck cancer. Antioxidants, such as coenzyme Q10 (CoQ(10)) and quercetin, a member of flavonoids present in red wine and tea, are thought to play a signi...
- Rho/ROCK and MAPK Signaling Pathways Are Involved in Glioblastoma Cell Migration and Proliferation
[作者:Zohrabian, VM; Forzani, B; Chau, ZL; Murali, R; Jhanwar-Uniyal, M,期刊:Anticancer Research, 页码:119-123 , 文章类型: Article,,卷期:2009年29-1]
- Background: Glioblastoma multiforme (GBM) remains the most aggressive and frequently occurring brain neoplasm. Members of the Rho family of small GTP-binding proteins, including Rho, Rac, and Cdc42, have been shown to pa...
- Adhesion/Growth-regulatory Tissue Lectin Galectin-1 in Relation to Angiogenesis/Lymphocyte Infiltration and Prognostic Relevance of Stromal Up-regulation in Laryngeal Carcinomas
[作者:Saussez, S; Decaestecker, C; Cludts, S; Ernoux, P; Chevalier, D; Smetana, K; Andre, S; Leroy, X; Gabius, HJ,期刊:Anticancer Research, 页码:59-65 , 文章类型: Article,,卷期:2009年29-1]
- Background: Galectin-1 has been found to modulate lymphocyte invasion in inflammation and to be involved in angiogenesis in models, thus prompting examination of its clinical relevance in laryngeal cancer. Patients and M...
- Preclinical Evaluation of Adoptive Cell Therapy for Patients with Metastatic Renal Cell Carcinoma
[作者:Markel, G; Cohen-Sinai, T; Besser, MJ; Oved, K; Itzhaki, O; Seidman, R; Treves, AJ; Fridman, E; Keisari, Y; Dotan, Z; Ramon, J; Schachter, J,期刊:Anticancer Research, 页码:145-154 , 文章类型: Article,,卷期:2009年29-1]
- Background: Interleukin-2 (IL-2) shows encouraging clinical results in metastatic renal cell carcinoma (RCC) patients, but is limited by substantial toxicity. Cell-based therapy holds a promise, but past attempts in RCC ...
- Expression of 25-Hydroxyvitamin D-1-alpha-Hydroxylase, and Vitamin D Receptor mRNA in Normal and Malignant Breast Tissue
[作者:McCarthy, K; Laban, C; Bustin, SA; Ogunkolade, W; Khalaf, S; Carpenter, R; Jenkins, PJ,期刊:Anticancer Research, 页码:155-157 , 文章类型: Article,,卷期:2009年29-1]
- Vitamin D has anti-proliferative and proapoptotic effects on several cell types, including breast cancer cells. There have been no studies quantifying the expression of the enzyme 25-hydroxyvitamin D-1-alpha-hydroxylase ...
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