- A Protein-bound Polysaccharide, PSK, Enhances Tumor Suppression Induced by Docetaxel in a Gastric Cancer Xenograft Model
[作者:Yamasaki, A; Shoda, M; Iijima, H; Nagai, S; Wada, J; Suzuki, H; Chikazawa, N; Tasaka, T; Kameda, C; Tanaka, H; Ikebe, M; Jo, E; Sato, N; Nakamura, M; Sekine, F; Morisaki, T; Katano, M,期刊:Anticancer Research, 页码:843-850 , 文章类型: Article,,卷期:2009年29-3]
- Background: We have reported previously that docetaxel (TXT) induces apoptosis and nuclear factor-kappaB (NF-kappa B) activation, and that blockade of NF-kappa B activation augments TXT-induced apoptosis in human gastric...
- Claudin-1 Protein is a Major Factor Involved in the Tumorigenesis of Colorectal Cancer
[作者:Huo, Q; Kinugasa, T; Wang, L; Huang, J; Zhao, J; Shibaguchi, H; Kuroki, M; Tanaka, T; Yamashita, Y; Nabeshima, K; Iwasaki, H; Kuroki, M,期刊:Anticancer Research, 页码:851-857 , 文章类型: Article,,卷期:2009年29-3]
- Background: The molecular and morphological alterations of the tight junctions in colorectal cancer (CRC) are still poorly understood. The possible involvement of claudin-1 (CL-1), one of the major tight junctional prote...
- Intracellular Localization of CD14 Protein in Intestinal Macrophages
[作者:Yoshioka, N; Taniguchi, Y; Yoshida, A; Nakata, K; Nishizawa, T; Inagawa, H; Kohchi, C; Soma, GI,期刊:Anticancer Research, 页码:865-869 , 文章类型: Article,,卷期:2009年29-3]
- Background: Our research is focused on intestinal macrophages, which are believed to contribute to the maintenance of intestinal homeostasis. In addition, intestinal macrophages are unique in that there is at? impairment...
- The Hedgehog Pathway Is a Possible Therapeutic Target for Patients with Estrogen Receptor-negative Breast Cancer
[作者:Kameda, C; Tanaka, H; Yamasaki, A; Nakamura, M; Koga, K; Sato, N; Kubo, M; Kuroki, S; Tanaka, M; Katano, M,期刊:Anticancer Research, 页码:871-879 , 文章类型: Article,,卷期:2009年29-3]
- Understanding the expression patterns of estrogen receptor-a (ER alpha) is essential for determining therapeutic strategies for patients with breast cancer. The prognosis of patients with ER alpha-negative breast cancer ...
- Effects of Focused Ultrasound Sonodynamic Treatment on the Rat Blood-Brain Barrier
[作者:Yoshino, SI; Fukushima, T; Hayashi, S; Nonaka, M; Ogawa, K; Sasaki, K; Umemura, SI,期刊:Anticancer Research, 页码:889-895 , 文章类型: Article,,卷期:2009年29-3]
- Background: Ultrasound has recently been applied to the treatment as well as the diagnosis of various pathologies, and its antitumor effects in the treatment of human cancer and experimental models of cancer have been de...
- Efficacy of Temozolomide Treatment in Patients with High-grade Glioma
[作者:Oshiro, S; Tsugu, H; Komatsu, F; Ohmura, T; Ohta, M; Sakamoto, S; Fukushima, T; Inoue, T,期刊:Anticancer Research, 页码:911-917 , 文章类型: Article,,卷期:2009年29-3]
- Background: Numerous studies have reported the clinical efficacy of temozolomide (TMZ) treatment for high-grade glioma, but information on Japanese populations has been limited. This study assessed the safety and early o...
- Utility and Safety of LPS-based Fermented Flour Extract as a Macrophage Activator
[作者:Taniguchi, Y; Yoshioka, N; Nishizawa, T; Inagawa, H; Kohchi, C; Soma, GI,期刊:Anticancer Research, 页码:859-864 , 文章类型: Article,,卷期:2009年29-3]
- The immune system is part of the homeostasis system. Our research is focused on ways to maintain health, with an emphasis on the role of macrophages. We have hypothesized that tissue macrophages form a systemic network w...
- Infliximab Treatment for Anal Fistula in Patients with Crohn's Disease
[作者:Higashi, D; Futami, K; Egawa, Y; Hirano, K; Tomiyasu, T; Ishibashi, Y; Simomura, T; Nii, K; Kuroki, H; Maekawa, T; Ono, Y; Matsui, T,期刊:Anticancer Research, 页码:927-933 , 文章类型: Article,,卷期:2009年29-3]
- Background: Infliximab has played a central role in the treatment of luminal Crohn's disease (CD) due to its great usefulness. Although the seton placement has been widely used for the treatment of anal fistula in patien...
- The Contribution of Vascular Endothelial Growth Factor to the Induction of Regulatory T-Cells in Malignant Effusions
[作者:Wada, J; Suzuki, H; Fuchino, R; Yamasaki, A; Nagai, S; Yanai, K; Koga, K; Nakamura, M; Tanaka, M; Morisaki, T; Katano, M,期刊:Anticancer Research, 页码:881-888 , 文章类型: Article,,卷期:2009年29-3]
- It has been suggested that immunosuppressive cytokines such as transforming growth factor beta (TGF-beta) and interleukin 10 play an important role in the induction and/or maintenance of regulator), T-cells (Tregs) in pa...
- Sonodynamic Therapy Consisting of Focused Ultrasound and a Photosensitizer Causes a Selective Antitumor Effect in a Rat Intracranial Glioma Model
[作者:Nonaka, M; Yamamoto, M; Yoshino, S; Umemura, SI; Sasaki, K; Fukushima, T,期刊:Anticancer Research, 页码:943-950 , 文章类型: Article,,卷期:2009年29-3]
- In this study we sought to determine the optimal focused ultrasound acoustic conditions with photosensitizers for the ablation of experimental intracranial glioma in rats. Materials and Methods: Normal rat brains were so...
- Mechanism of Photofrin-enhanced Ultrasound-induced Human Glioma Cell Death
[作者:Hayashi, S; Yamamoto, M; Tachibana, K; Ueno, Y; Bu, GJ; Fukushima, T,期刊:Anticancer Research, 页码:897-905 , 文章类型: Article,,卷期:2009年29-3]
- Background: Low-intensity ultrasound showed tumor cell killing by a non-thermal effect in human leukemia cells. The aim of our study was to investigate the efficacy of low-intensity ultrasound on malignant astrocytic tum...
- The Role of Toll-like Receptor 2 in Survival Strategies of Mycobacterium tuberculosis in Macrophage Phagosomes
[作者:Yoshida, A; Inagawa, H; Kohchi, C; Nishizawa, T; Soma, GI,期刊:Anticancer Research, 页码:907-910 , 文章类型: Article,,卷期:2009年29-3]
- Mycobacterium tuberculosis (Mtb), an intracellular pathogen, is phagocytosed by alveolar macrophage but it is not digested; it survives, proliferates and establishes Mtb infections. The long-term survival mechanism of Mt...
- Management of Pilomyxoid Astrocytomas: Our Experience
[作者:Tsugu, H; Oshiro, S; Yanai, F; Komatsu, F; Abe, H; Fukushima, T; Nomura, Y; Matsumoto, S; Nabeshima, K; Takano, K; Utsunomiya, H,期刊:Anticancer Research, 页码:919-926 , 文章类型: Article,,卷期:2009年29-3]
- Background: Pilomyxoid astrocytoma (PMA) shows a higher rate of recurrence and cerebrospinal fluid (CSF) dissemination than does pilocytic astrocytoma (PA). In this article, we discuss the treatment of PMA. Materials and...
- Flexible Structure of Cytochrome P450: Promiscuity of Ligand Binding in the CYP3A4 Heme Pocket
[作者:Ohkura, K; Kawaguchi, Y; Watanabe, Y; Masubuchi, Y; Shinohara, Y; Hori, H,期刊:Anticancer Research, 页码:935-942 , 文章类型: Article,,卷期:2009年29-3]
- Background: CYP3A4 is the most abundant xenobiotic-metabolizing cytochrome P450 isoform. We examined the structural features of the CYP3A4 molecule with regard to ligand access. Materials and Metho.-Is: The deleted amino...
- Proceedings of the 11th Annual Meeting of the Society for Biotherapeutic Approaches, December 1, 2007, Tokyo, Japan Preface
[作者:Soma, GI; Kato, M; Terada, H,期刊:Anticancer Research, 页码:795-795 , 文章类型: Editorial Material,,卷期:2009年29-3]
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