- The Impact of Market Volatility on the Cell Therapy Industry
[作者:Brindley, DA; Reeve, BC; Sahlman, WA; Bonfiglio, GA; Davie, NL; Culme-Seymour, EJ; Mason, C,期刊:Cell Stem Cell, 页码:397-401 , 文章类型: Editorial Material,,卷期:2011年9-5]
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- Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts
[作者:Kim, J; Su, SC; Wang, HY; Cheng, AW; Cassady, JP; Lodato, MA; Lengner, CJ; Chung, CY; Dawlaty, MM; Tsai, LH; Jaenisch, R,期刊:Cell Stem Cell, 页码:413-419 , 文章类型: Article,,卷期:2011年9-5]
- Recent advances in somatic cell reprogramming have highlighted the plasticity of the somatic epigenome, particularly through demonstrations of direct lineage reprogramming of one somatic cell type to another by defined f...
- Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling
[作者:Kubin, T; Poling, J; Kostin, S; Gajawada, P; Hein, S; Rees, W; Wietelmann, A; Tanaka, M; Lorchner, H; Schimanski, S; Szibor, M; Warnecke, H; Braun, T,期刊:Cell Stem Cell, 页码:420-432 , 文章类型: Article,,卷期:2011年9-5]
- Cardiomyocyte remodeling, which includes partial dedifferentiation of cardiomyocytes, is a process that occurs during both acute and chronic disease processes. Here, we demonstrate that oncostatin M (OSM) is a major medi...
- Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy
[作者:Lonardo, E; Hermann, PC; Mueller, MT; Huber, S; Balic, A; Miranda-Lorenzo, I; Zagorac, S; Alcala, S; Roderiguez-Arabaolaza, I; Ramirez, JC; Torres-Ruiz, R; Garcia, E; Hidalgo, M; Cebrian, DA; Heuchel, R; Lohr, M; Berger, F; Bartenstein, P; Aicher, A; Heeschen, C,期刊:Cell Stem Cell, 页码:433-446 , 文章类型: Article,,卷期:2011年9-5]
- Nodal and Activin belong to the TGF-beta superfamily and are important regulators of embryonic stem cell fate. Here we investigated whether Nodal and Activin regulate self-renewal of pancreatic cancer stem cells. Nodal a...
- Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
[作者:Magri, L; Cambiaghi, M; Cominelli, M; Alfaro-Cervello, C; Cursi, M; Pala, M; Bulfone, A; Garcia-Verdugo, JM; Leocani, L; Minicucci, F; Poliani, PL; Galli, R,期刊:Cell Stem Cell, 页码:447-462 , 文章类型: Article,,卷期:2011年9-5]
- Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder characterized by hamartomatous neurological lesions that exhibit abnormal cell proliferation and differentiation. Hyperactivation of mTOR pathway by muta...
- Rac Mediates Mouse Spermatogonial Stem Cell Homing to Germline Niches by Regulating Transmigration through the Blood-Testis Barrier
[作者:Takashima, S; Kanatsu-Shinohara, M; Tanaka, T; Takehashi, M; Morimoto, H; Shinohara, T,期刊:Cell Stem Cell, 页码:463-475 , 文章类型: Article,,卷期:2011年9-5]
- The homing ability of spermatogonial stem cells (SSCs) allows them to migrate into niches after being transplantated into infertile testes. Transplanted SSCs attach to Sertoli cells and transmigrate through the blood-tes...
- Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients
[作者:Melo, FDE; Colak, S; Buikhuisen, J; Koster, J; Cameron, K; de Jong, JH; Tuynman, JB; Prasetyanti, PR; Fessler, E; van den Bergh, SP; Rodermond, H; Dekker, E; van der Loos, CM; Pals, ST; van de Vijver, MJ; Versteeg, R; Richel, DJ; Vermeulen, L; Medema, JP,期刊:Cell Stem Cell, 页码:476-485 , 文章类型: Article,,卷期:2011年9-5]
- Gene signatures derived from cancer stem cells (CSCs) predict tumor recurrence for many forms of cancer. Here, we derived a gene signature for colorectal CSCs defined by high Wnt signaling activity, which in agreement wi...
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