- Pluripotency without Max
[作者:Wiese, KE; Eilers, M,期刊:Cell Stem Cell, 页码:4-6 , 文章类型: Editorial Material,,卷期:2011年9-1]
- Myc/Max complexes are thought to be essential for maintaining pluripotency and self-renewal of embryonic stem cells (ESCs). In this issue of Cell Stem Cell, Hishida et al. (2011) provide genetic evidence that this requir...
- Funding Translational Work in Cell-Based Therapy
[作者:Rao, MS,期刊:Cell Stem Cell, 页码:7-10 , 文章类型: Editorial Material,,卷期:2011年9-1]
- The cell therapy branch of the regenerative medicine field has been innovative in developing new models of delivery and development and identifying alternative sources of funding. We discuss the implications of these cha...
- The MSC: An Injury Drugstore
[作者:Caplan, AI; Correa, D,期刊:Cell Stem Cell, 页码:11-15 , 文章类型: Article,,卷期:2011年9-1]
- Now that mesenchymal stem cells (MSCs) have been shown to be perivascular in vivo, the existing traditional view that focuses on the multipotent differentiation capacity of these cells should be expanded to include their...
- Cell Fate Potential of Human Pluripotent Stem Cells Is Encoded by Histone Modifications
[作者:Hong, SH; Pampalli, S; Lee, JB; McNicol, J; Collins, T; Draper, JS; Bhatia, M,期刊:Cell Stem Cell, 页码:24-36 , 文章类型: Article,,卷期:2011年9-1]
- Human embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equipotent developmental potential. However, disparate responses to differentiation stimuli functionally illustrate that hESCs gen...
- Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms
[作者:Hishida, T; Nozaki, Y; Nakachi, Y; Mizuno, Y; Okazaki, Y; Ema, M; Takahashi, S; Nishimoto, M; Okuda, A,期刊:Cell Stem Cell, 页码:37-49 , 文章类型: Article,,卷期:2011年9-1]
- Embryonic stem cells (ESCs) can self-renew indefinitely under the governance of ESC-specific transcriptional circuitries in which each transcriptional factor regulates distinct or overlapping sets of genes with other fac...
- CD24(+) Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation
[作者:Lee, TKW; Castilho, A; Cheung, VCH; Tang, KH; Ma, S; Irene, OLN,期刊:Cell Stem Cell, 页码:50-63 , 文章类型: Article,,卷期:2011年9-1]
- Tumor-initiating cells (T-ICs) are a subpopulation of chemoresistant tumor cells that have been shown to cause tumor recurrence upon chemotherapy. Identification of T-ICs and their related pathways are therefore prioriti...
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