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  • Emerging common themes in regulation of PIKKs and PI3Ks
    [作者:Lempiainen, H; Halazonetis, TD,期刊:EMBO journal, 页码:3067-3073 , 文章类型: Review,,卷期:2009年28-20]
  • Phosphatidylinositol-3 kinase-related kinases (PIKKs) comprise a family of protein kinases that respond to various stresses, including DNA damage, blocks in DNA replication, availability of nutrients and errors in mRNA s...
  • Editing independent effects of ADARs on the miRNA/siRNA pathways
    [作者:Heale, BSE; Keegan, LP; McGurk, L; Michlewski, G; Brindle, J; Stanton, CM; Caceres, JF; O'Connell, MA,期刊:EMBO journal, 页码:3145-3156 , 文章类型: Article,,卷期:2009年28-20]
  • Adenosine deaminases acting on RNA (ADARs) are best known for altering the coding sequences of mRNA through RNA editing, as in the GluR-B Q/R site. ADARs have also been shown to affect RNA interference (RNAi) and microRN...
  • Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
    [作者:Parsons, JL; Tait, PS; Finch, D; Dianova, II; Edelmann, MJ; Khoronenkova, SV; Kessler, BM; Sharma, RA; McKenna, WG; Dianov, GL,期刊:EMBO journal, 页码:3207-3215 , 文章类型: Article,,卷期:2009年28-20]
  • Base excision repair (BER) is the major cellular pathway involved in removal of endogenous/spontaneous DNA lesions. Here, we study the mechanism that controls the steady-state levels of BER enzymes in human cells. By fra...