- miRNA processing turned upside down
[作者：Schwab, R; Voinnet, O,期刊：EMBO journal, 页码：3633-3634 , 文章类型： Editorial Material，,卷期：2009年28-23]
- MicroRNAs are 19-22 nt-long RNAs that regulate eukaryotic gene expression. They are processed from stem-loop containing precursor transcripts by RNAse III enzymes of the Dicer family. In this issue of the EMBO Journal, a...
- Histone H1 binding is inhibited by histone variant H3.3
[作者：Braunschweig, U; Hogan, GJ; Pagie, L; van Steensel, B,期刊：EMBO journal, 页码：3635-3645 , 文章类型： Article，,卷期：2009年28-23]
- Linker histones are involved in the formation of higher-order chromatin structure and the regulation of specific genes, yet it remains unclear what their principal binding determinants are. We generated a genome-wide hig...
- Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK
[作者：Das, BB; Antony, S; Gupta, S; Dexheimer, TS; Redon, CE; Garfield, S; Shiloh, Y; Pommier, Y,期刊：EMBO journal, 页码：3667-3680 , 文章类型： Article，,卷期：2009年28-23]
- Human tyrosyl-DNA phosphodiesterase (TDP1) hydrolyzes the phosphodiester bond at a DNA 3' end linked to a tyrosyl moiety. This type of linkage is found at stalled topoisomerase I (Top1)-DNA covalent complexes, and TDP1 h...
- Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion
[作者：Errico, A; Cosentino, C; Rivera, T; Losada, A; Schwob, E; Hunt, T; Costanzo, V,期刊：EMBO journal, 页码：3681-3692 , 文章类型： Article，,卷期：2009年28-23]
- The Tipin/Tim1 complex plays an important role in the S-phase checkpoint and replication fork stability. However, the biochemical function of this complex is poorly understood. Using Xenopus laevis egg extract we show th...
- SCFDia2 regulates DNA replication forks during S-phase in budding yeast
[作者：Mimura, S; Komata, M; Kishi, T; Shirahige, K; Kamura, T,期刊：EMBO journal, 页码：3693-3705 , 文章类型： Article，,卷期：2009年28-23]
- Dia2 is an F-box protein, which is involved in the regulation of DNA replication in the budding yeast Saccharomyces cerevisiae. The function of Dia2, however, remains largely unknown. In this study, we report that Dia2 i...
- Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila
[作者：Bauer, R; Voelzmann, A; Breiden, B; Schepers, U; Farwanah, H; Hahn, I; Eckardt, F; Sandhoff, K; Hoch, M,期刊：EMBO journal, 页码：3706-3716 , 文章类型： Article，,卷期：2009年28-23]
- Ceramide synthases are highly conserved transmembrane proteins involved in the biosynthesis of sphingolipids, which are essential structural components of eukaryotic membranes and can act as second messengers regulating ...
- Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour
[作者：Taniguchi, S; Nakazawa, T; Tanimura, A; Kiyama, Y; Tezuka, T; Watabe, AM; Katayama, N; Yokoyama, K; Inoue, T; Izumi-Nakaseko, H; Kakuta, S; Sudo, K; Iwakura, Y; Umemori, H; Inoue, T; Murphy, NP; Hashimoto, K; Kano, M; Manabe, T; Yamamoto, T,期刊：EMBO journal, 页码：3717-3729 , 文章类型： Article，,卷期：2009年28-23]
- Major depressive and bipolar disorders are serious illnesses that affect millions of people. Growing evidence implicates glutamate signalling in depression, though the molecular mechanism by which glutamate signalling re...
- Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules
[作者：Howe, C; Garstka, M; Al-Balushi, M; Ghanem, E; Antoniou, AN; Fritzsche, S; Jankevicius, G; Kontouli, N; Schneeweiss, C; Williams, A; Elliott, T; Springer, S,期刊：EMBO journal, 页码：3730-3744 , 文章类型： Article，,卷期：2009年28-23]
- Calreticulin is a lectin chaperone of the endoplasmic reticulum (ER). In calreticulin-deficient cells, major histocompatibility complex (MHC) class I molecules travel to the cell surface in association with a sub-optimal...
- Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip
[作者：Roodveldt, C; Bertoncini, CW; Andersson, A; van der Goot, AT; Hsu, ST; Fernandez-Montesinos, R; de Jong, J; van Ham, TJ; Nollen, EA; Pozo, D; Christodoulou, J; Dobson, CM,期刊：EMBO journal, 页码：3758-3770 , 文章类型： Article，,卷期：2009年28-23]
- The ATP-dependent protein chaperone heat-shock protein 70 (Hsp70) displays broad anti-aggregation functions and has a critical function in preventing protein misfolding pathologies. According to in vitro and in vivo mode...
- Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy (vol 28, pg 2244, 2009)
[作者：Vergne, I; Roberts, E; Elmaoued, RA; Tosch, V; Delgado, MA; Proikas-Cezanne, T; Laporte, J; Deretic, V,期刊：EMBO journal, 页码：3780-3780 , 文章类型： Correction，,卷期：2009年28-23]
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- Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands (vol 28, pg 3579, 2009)
[作者：Florence, WC; Xia, CF; Gordy, LE; Chen, WL; Zhang, YL; Scott-Browne, J; Kinjo, Y; Yu, KOA; Keshipeddy, S; Pellicci, DG; Patel, O; Kjer-Nielsen, L; McCluskey, J; Godfrey, DI; Rossjohn, J; Richardson, SK; Porcelli, SA; Howell, AR; Hayakawa, K; Gapin, L; Zajonc, DM; Wang, PG; Joyce, S,期刊：EMBO journal, 页码：3781-3781 , 文章类型： Correction，,卷期：2009年28-23]
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