- Dendritic tiling through TOR signalling
[作者:Hong, WZ; Luo, LQ,期刊:EMBO journal, 页码:3783-3784 , 文章类型: Editorial Material,,卷期:2009年28-24]
- In many sensory systems, dendrites of sensory neurons cover an entire sensory field in a complete and non-redundant manner, a phenomenon called dendritic tiling. Previous studies have identified the Tricornered (Trc) kin...
- Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin
[作者:Bancaud, A; Huet, S; Daigle, N; Mozziconacci, J; Beaudouin, J; Ellenberg, J,期刊:EMBO journal, 页码:3785-3798 , 文章类型: Article,,卷期:2009年28-24]
- The nucleus of eukaryotes is organized into functional compartments, the two most prominent being heterochromatin and nucleoli. These structures are highly enriched in DNA, proteins or RNA, and thus thought to be crowded...
- The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis
[作者:Lebaron, S; Papin, C; Capeyrou, R; Chen, YL; Froment, C; Monsarrat, B; Caizergues-Ferrer, M; Grigoriev, M; Henry, Y,期刊:EMBO journal, 页码:3808-3819 , 文章类型: Article,,卷期:2009年28-24]
- Prp43p is a RNA helicase required for pre-mRNA splicing and for the synthesis of large and small ribosomal subunits. The molecular functions and modes of regulation of Prp43p during ribosome biogenesis remain unknown. We...
- Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines
[作者:Nishida, KM; Okada, TN; Kawamura, T; Mituyama, T; Kawamura, Y; Inagaki, S; Huang, HD; Chen, DH; Kodama, T; Siomi, H; Siomi, MC,期刊:EMBO journal, 页码:3820-3831 , 文章类型: Article,,卷期:2009年28-24]
- In Drosophila, the PIWI proteins, Aubergine (Aub), AGO3, and Piwi are expressed in germlines and function in silencing transposons by associating with PIWI-interacting RNAs (piRNAs). Recent studies show that PIWI protein...
- Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA
[作者:Djupedal, I; Kos-Braun, IC; Mosher, RA; Soderholm, N; Simmer, F; Hardcastle, TJ; Fender, A; Heidrich, N; Kagansky, A; Bayne, E; Wagner, EGH; Baulcombe, DC; Allshire, RC; Ekwall, K,期刊:EMBO journal, 页码:3832-3844 , 文章类型: Article,,卷期:2009年28-24]
- The formation of heterochromatin at the centromeres in fission yeast depends on transcription of the outer repeats. These transcripts are processed into siRNAs that target homologous loci for heterochromatin formation. H...
- Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae
[作者:Siergiejuk, E; Scott, DC; Schulman, BA; Hofmann, K; Kurz, T; Peter, M,期刊:EMBO journal, 页码:3845-3856 , 文章类型: Article,,卷期:2009年28-24]
- Cullin-based E3 ubiquitin ligases are activated through covalent modification of the cullin subunit by the ubiquitin-like protein Nedd8. Cullin neddylation dissociates the ligase assembly inhibitor Cand1, and promotes E2...
- ATM activates p53 by regulating MDM2 oligomerization and E3 processivity
[作者:Cheng, Q; Chen, LH; Li, ZY; Lane, WS; Chen, JD,期刊:EMBO journal, 页码:3857-3867 , 文章类型: Article,,卷期:2009年28-24]
- Rapid activation of p53 by ionizing irradiation is a classic DNA damage response mediated by the ATM kinase. However, the major signalling target and mechanism that lead to p53 stabilization are unknown. We show in this ...
- Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells
[作者:Kuraishi, T; Nakagawa, Y; Nagaosa, K; Hashimoto, Y; Ishimoto, T; Moki, T; Fujita, Y; Nakayama, H; Dohmae, N; Shiratsuchi, A; Yamamoto, N; Ueda, K; Yamaguchi, M; Awasaki, T; Nakanishi, Y,期刊:EMBO journal, 页码:3868-3878 , 文章类型: Article,,卷期:2009年28-24]
- Phagocytic removal of cells undergoing apoptosis is necessary for animal development and tissue homeostasis. Draper, a homologue of the Caenorhabditis elegans phagocytosis receptor CED-1, is responsible for the phagocyto...
- The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway
[作者:Koike-Kumagai, M; Yasunaga, K; Morikawa, R; Kanamori, T; Emoto, K,期刊:EMBO journal, 页码:3879-3892 , 文章类型: Article,,卷期:2009年28-24]
- To cover the receptive field completely and non-redundantly, neurons of certain functional groups arrange tiling of their dendrites. In Drosophila class IV dendrite arborization (da) neurons, the NDR family kinase Tricor...
- Inhibition of the shade avoidance response by formation of non-DNA binding bHLH heterodimers
[作者:Hornitschek, P; Lorrain, S; Zoete, V; Michielin, O; Fankhauser, C,期刊:EMBO journal, 页码:3893-3902 , 文章类型: Article,,卷期:2009年28-24]
- In shade-intolerant plants such as Arabidopsis, a reduction in the red/far-red (R/FR) ratio, indicative of competition from other plants, triggers a suite of responses known as the shade avoidance syndrome (SAS). The phy...
- Molecular architecture of Streptococcus pneumoniae TIGR4 pili
[作者:Hilleringmann, M; Ringler, P; Muller, SA; De Angelis, G; Rappuoli, R; Ferlenghi, I; Engel, A,期刊:EMBO journal, 页码:3921-3930 , 文章类型: Article,,卷期:2009年28-24]
- Although the pili of Gram-positive bacteria are putative virulence factors, little is known about their structure. Here we describe the molecular architecture of pilus-1 of Streptococcus pneumoniae, which is a major caus...
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