- Host Stress and Virulence Expression in Intestinal Pathogens: Development of Therapeutic Strategies Using Mice and C. elegans
[作者:Zaborina, O; Zaborin, A; Romanowski, K; Babrowski, T; Alverdy, J,期刊:Current Pharmaceutical Design, 页码:1254-1260 , 文章类型: Review,,卷期:2011年17-13]
- The intestinal tract of a host exposed to extreme physiologic stress and modern medical intervention represents a relatively unexplored yet important area of infection research, given the frequency with which this site b...
- Humanized SCID Mice Models of SLE
[作者:Kerekov, N; Mihaylova, N; Prechl, J; Tchorbanov, A,期刊:Current Pharmaceutical Design, 页码:1261-1266 , 文章类型: Review,,卷期:2011年17-13]
- The pathological DNA-specific B cells in Systemic lupus erythematosus are a logical target for a selected therapeutic intervention. It has been recently shown that complement receptor type 1 on human B and T-lymphocytes ...
- Microbial Efflux Pump Inhibition: Tactics and Strategies
[作者:Tegos, GP; Haynes, M; Strouse, J; Khan, MMT; Bologa, CG; Oprea, TI; Sklar, LA,期刊:Current Pharmaceutical Design, 页码:1291-1302 , 文章类型: Review,,卷期:2011年17-13]
- Traditional antimicrobials are increasingly suffering from the emergence of multidrug resistance among pathogenic microorganisms. To overcome these deficiencies, a range of novel approaches to control microbial infection...
- Drug Discovery of Antimicrobial Photosensitizers Using Animal Models
[作者:Sharma, SK; Dai, TH; Kharkwal, GB; Huang, YY; Huang, LY; De Arce, VJB; Tegos, GP; Hamblin, MR,期刊:Current Pharmaceutical Design, 页码:1303-1319 , 文章类型: Review,,卷期:2011年17-13]
- Antimicrobial photodynamic therapy (aPDT) is an emerging alternative to antibiotics motivated by growing problems with multi-drug resistant pathogens. aPDT uses non-toxic dyes or photosensitizers (PS) in combination with...
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