- GABA(A) Receptor Signaling Induces Osmotic Swelling and Cell Cycle Activation of Neonatal Prominin(+) Precursors
[作者:Cesetti, T; Fila, T; Obernier, K; Bengtson, CP; Li, YT; Mandl, C; Holzl-Wenig, G; Ciccolini, F,期刊:Stem Cells, 页码:307-319 , 文章类型: Article,,卷期:2011年29-2]
- Signal-regulated changes in cell size affect cell division and survival and therefore are central to tissue morphogenesis and homeostasis. In this respect, GABA receptors (GABA(A)Rs) are of particular interest because al...
- Sur8/Shoc2 Involves Both Inhibition of Differentiation and Maintenance of Self-Renewal of Neural Progenitor Cells via Modulation of Extracellular Signal-Regulated Kinase Signaling
[作者:Moon, BS; Kim, HY; Kim, MY; Yang, DH; Lee, JM; Cho, KW; Jung, HS; Choi, KY,期刊:Stem Cells, 页码:320-331 , 文章类型: Article,,卷期:2011年29-2]
- Sur8/Shoc2 is a scaffold protein that regulates the Ras-extracellular signal-regulated kinase (ERK) pathway. However, the roles of Sur8 in cellular physiologies are poorly understood. In this study, Sur8 was severely rep...
- The Rho Kinase Pathway Regulates Mouse Adult Neural Precursor Cell Migration
[作者:Leong, SY; Faux, CH; Turbic, A; Dixon, KJ; Turnley, AM,期刊:Stem Cells, 页码:332-343 , 文章类型: Article,,卷期:2011年29-2]
- Adult neural precursor cells (NPCs) in the subventricular zone (SVZ) normally migrate via the rostral migratory stream (RMS) to the olfactory bulb (OB). Following neural injury, they also migrate to the site of damage. T...
- Adult Human Muller Glia Cells Are a Highly Efficient Source of Rod Photoreceptors
[作者:Giannelli, SG; Demontis, GC; Pertile, G; Rama, P; Broccoli, V,期刊:Stem Cells, 页码:344-356 , 文章类型: Article,,卷期:2011年29-2]
- There is growing evidence that Muller glia cells (MGCs) might act as regenerative elements in injured retinas of fishes and amniotes. However, their differentiation potential in humans is yet unknown. We isolated Muller ...
- Pretreatment of Human Mesenchymal Stem Cells with Pioglitazone Improved Efficiency of Cardiomyogenic Transdifferentiation and Cardiac Function
[作者:Shinmura, D; Togashi, I; Miyoshi, S; Nishiyama, N; Hida, N; Tsuji, H; Tsuruta, H; Segawa, K; Tsukada, Y; Ogawa, S; Umezawa, A,期刊:Stem Cells, 页码:357-366 , 文章类型: Article,,卷期:2011年29-2]
- The efficacy of transplantation of default human marrow-derived mesenchymal stem cells (MSCs) was modest. In this study, our challenge was to improve the efficacy of MSC transplantation in vivo by pretreatment of MSCs wi...
- A Fibrin Patch-Based Enhanced Delivery of Human Embryonic Stem Cell-Derived Vascular Cell Transplantation in a Porcine Model of Postinfarction Left Ventricular Remodeling
[作者:Xiong, QA; Hill, KL; Li, QL; Suntharalingam, P; Mansoor, A; Wang, XH; Jameel, MN; Zhang, PY; Swingen, C; Kaufman, DS; Zhang, JY,期刊:Stem Cells, 页码:367-375 , 文章类型: Article,,卷期:2011年29-2]
- It is unknown how to use human embryonic stem cell (hESC) to effectively treat hearts with postinfarction left ventricular (LV) remodeling. Using a porcine model of postinfarction LV remodeling, this study examined the f...
- Growth Factor Independence 1 Protects Hematopoietic Stem Cells Against Apoptosis but Also Prevents the Development of a Myeloproliferative-Like Disease
[作者:Khandanpour, C; Kosan, C; Gaudreau, MC; Duhrsen, U; Hebert, J; Zeng, H; Moroy, T,期刊:Stem Cells, 页码:376-385 , 文章类型: Article,,卷期:2011年29-2]
- The regulation of gene transcription is elementary for the function of hematopoietic stem cells (HSCs). The transcriptional repressor growth factor independence 1 (Gfi1) restricts HSC proliferation and is essential to ma...
- FUS-CHOP Fusion Protein Expression Coupled to p53 Deficiency Induces Liposarcoma in Mouse but Not in Human Adipose-Derived Mesenchymal Stem/Stromal Cells
[作者:Rodriguez, R; Rubio, R; Gutierrez-Aranda, I; Melen, GJ; Elosua, C; Garcia-Castro, J; Menendez, P,期刊:Stem Cells, 页码:179-192 , 文章类型: Article,,卷期:2011年29-2]
- Human sarcomas have been modeled in mice by expression of specific fusion genes in mesenchymal stem cells (MSCs). However, sarcoma models based on human MSCs are still missing. We attempted to develop a model of liposarc...
- Osteoblasts Derived from Induced Pluripotent Stem Cells Form Calcified Structures in Scaffolds Both in Vitro and in Vivo
[作者:Bilousova, G; Jun, DH; King, KB; De Langhe, S; Chick, WS; Torchia, EC; Chow, KS; Klemm, DJ; Roop, DR; Majka, SM,期刊:Stem Cells, 页码:206-216 , 文章类型: Article,,卷期:2011年29-2]
- Reprogramming somatic cells into an ESC-like state, or induced pluripotent stem (iPS) cells, has emerged as a promising new venue for customized cell therapies. In this study, we performed directed differentiation to ass...
- An Endothelial Cell Niche Induces Hepatic Specification Through Dual Repression of Wnt and Notch Signaling
[作者:Han, SY; Dziedzic, N; Gadue, P; Keller, GM; Gouon-Evans, V,期刊:Stem Cells, 页码:217-228 , 文章类型: Article,,卷期:2011年29-2]
- Complex cross-talk between endoderm and the microenvironment is an absolute requirement to orchestrate hepatic specification and expansion. In the mouse, the septum transversum and cardiac mesoderm, through secreted bone...
- PRC2 Complexes with JARID2, MTF2, and esPRC2p48 in ES Cells to Modulate ES Cell Pluripotency and Somatic Cell Reprograming
[作者:Zhang, Z; Jones, A; Sun, CW; Li, C; Chang, CW; Joo, HY; Dai, QA; Mysliwiec, MR; Wu, LC; Guo, YH; Yang, W; Liu, KM; Pawlik, KM; Erdjument-Bromage, H; Tempst, P; Lee, Y; Min, JR; Townes, TM; Wang, HB,期刊:Stem Cells, 页码:229-240 , 文章类型: Article,,卷期:2011年29-2]
- Polycomb repressive complex two (PRC2) has been implicated in embryonic stem (ES) cell pluripotency; however, the mechanistic roles of this complex are unclear. It was assumed that ES cells contain PRC2 with the same sub...
- A Nonhuman Primate Model for Urinary Bladder Regeneration Using Autologous Sources of Bone Marrow-Derived Mesenchymal Stem Cells
[作者:Sharma, AK; Bury, MI; Marks, AJ; Fuller, NJ; Meisner, JW; Tapaskar, N; Halliday, LC; Matoka, DJ; Cheng, EY,期刊:Stem Cells, 页码:241-250 , 文章类型: Article,,卷期:2011年29-2]
- Animal models that have been used to examine the regenerative capacity of cell-seeded scaffolds in a urinary bladder augmentation model have ultimately translated poorly in the clinical setting. This may be due to a numb...
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