- A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo
[作者:Cheng, QF; Tucker, EI; Pine, MS; Sisler, I; Matafonov, A; Sun, MF; White-Adams, TC; Smith, SA; Hanson, SR; McCarty, OJT; Renne, T; Gruber, A; Gailani, D,期刊:Blood, 页码:3981-3989 , 文章类型: Article,,卷期:2010年116-19]
- Mice lacking factor XII (fXII) or factor XI (fXI) are resistant to experimentally-induced thrombosis, suggesting fXIIa activation of fXI contributes to thrombus formation in vivo. It is not clear whether this reaction ha...
- Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors
[作者:Shaw, PJ; Kan, FY; Ahn, KW; Spellman, SR; Aljurf, M; Ayas, M; Burke, M; Cairo, MS; Chen, AR; Davies, SM; Frangoul, H; Gajewski, J; Gale, RP; Godder, K; Hale, GA; Heemskerk, MBA; Horan, J; Kamani, N; Kasow, KA; Chan, KW; Lee, SJ; Leung, WH; Lewis, VA; Miklos, D; Oudshoorn, M; Petersdorf, EW; Ringden, O; Sanders, J; Schultz, KR; Seber, A; Setterholm, M; Wall, DA; Yu, LL; Pulsipher, MA,期刊:Blood, 页码:4007-4015 , 文章类型: Article,,卷期:2010年116-19]
- Although some trials have allowed matched or single human leukocyte antigen (HLA)-mismatched related donors (mmRDs) along with HLA-matched sibling donors (MSDs) for pediatric bone marrow transplantation in early-stage he...
- An in vivo model of double-unit cord blood transplantation that correlates with clinical engraftment
[作者:Eldjerou, LK; Chaudhury, S; Baisre-de Leon, A; He, M; Arcila, ME; Heller, G; O'Reilly, RJ; Barker, JN; Moore, MA,期刊:Blood, 页码:3999-4006 , 文章类型: Article,,卷期:2010年116-19]
- Double-unit cord blood transplantation (DCBT) appears to enhance engraftment despite sustained hematopoiesis usually being derived from a single unit. To investigate DCBT biology, in vitro and murine models were establis...
- A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy
[作者:Fox, CP; Haigh, TA; Taylor, GS; Long, HM; Lee, SP; Shannon-Lowe, C; O'Connor, S; Bollard, CM; Iqbal, J; Chan, WC; Rickinson, AB; Bell, AI; Rowe, M,期刊:Blood, 页码:3695-3704 , 文章类型: Article,,卷期:2010年116-19]
- Therapeutic targeting of virus-encoded proteins using cellular immunotherapy has proved successful for Epstein-Barr virus (EBV)-associated posttransplant lymphoproliferative disease. However, the more limited repertoire ...
- Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells
[作者:Coleman, PR; Hahn, CN; Grimshaw, M; Lu, Y; Li, XC; Brautigan, PJ; Beck, K; Stocker, R; Vadas, MA; Gamble, JR,期刊:Blood, 页码:4016-4024 , 文章类型: Article,,卷期:2010年116-19]
- Cellular senescence is a mechanism to inhibit the growth of mammalian cells after oncogenic activation, or in response to damage or stress. We describe here the identification of a novel gene, SENEX, that regulates stres...
- Identification and functional analysis of endothelial tip cell-enriched genes
[作者:del Toro, R; Prahst, C; Mathivet, T; Siegfried, G; Kaminker, JS; Larrivee, B; Breant, C; Duarte, A; Takakura, N; Fukamizu, A; Penninger, J; Eichmann, A,期刊:Blood, 页码:4025-4033 , 文章类型: Article,,卷期:2010年116-19]
- Sprouting of developing blood vessels is mediated by specialized motile endothelial cells localized at the tips of growing capillaries. Following behind the tip cells, endothelial stalk cells form the capillary lumen and...
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