- Ulipristal Acetate versus Leuprolide Acetate for Uterine Fibroids
[作者:Donnez, J; Tomaszewski, J; Vazquez, F; Bouchard, P; Lemieszczuk, B; Baro, F; Nouri, K; Selvaggi, L; Sodowski, K; Bestel, E; Terrill, P; Osterloh, I; Loumaye, E,期刊:New England Journal of Medicine, 页码:421-432 , 文章类型: Article,,卷期:2012年366-5]
- Background The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are unclear. Methods In this double-blin...
- Ulipristal Acetate versus Placebo for Fibroid Treatment before Surgery
[作者:Donnez, J; Tatarchuk, TF; Bouchard, P; Puscasiu, L; Zakharenko, NF; Ivanova, T; Ugocsai, G; Mara, M; Jilla, MP; Bestel, E; Terrill, P; Osterloh, I; Loumaye, E,期刊:New England Journal of Medicine, 页码:409-420 , 文章类型: Article,,卷期:2012年366-5]
- Background The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic uterine fibroids before surgery are uncertain. Methods We randomly assigned women with symptomatic fibroids, excessive uterin...
- Delayed Puberty
[作者:Palmert, MR; Dunkel, L,期刊:New England Journal of Medicine, 页码:443-453 , 文章类型: Article,,卷期:2012年366-5]
- A 14-year-old boy with an unremarkable medical history presents because of lack of pubertal development. He has always been relatively short, but his growth velocity is slowing as compared with that of his peers. His hei...
- ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma
[作者:Meyer, RM; Gospodarowicz, MK; Connors, JM; Pearcey, RG; Wells, WA; Winter, JN; Horning, SJ; Dar, AR; Shustik, C; Stewart, DA; Crump, M; Djurfeldt, MS; Chen, BSE; Shepherd, LE,期刊:New England Journal of Medicine, 页码:399-408 , 文章类型: Article,,卷期:2012年366-5]
- Background Chemotherapy plus radiation treatment is effective in controlling stage IA or IIA nonbulky Hodgkin's lymphoma in 90% of patients but is associated with late treatment-related deaths. Chemotherapy alone may imp...
- GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus
[作者:Ludvigsson, J; Krisky, D; Casas, R; Battelino, T; Castano, L; Greening, J; Kordonouri, O; Otonkoski, T; Pozzilli, P; Robert, JJ; Veeze, HJ; Palmer, J,期刊:New England Journal of Medicine, 页码:433-442 , 文章类型: Article,,卷期:2012年366-5]
- Background The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent...
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