- NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children
[作者：Vignali, M; Armour, CD; Chen, JY; Morrison, R; Castle, JC; Biery, MC; Bouzek, H; Moon, W; Babak, T; Fried, M; Raymond, CK; Duffy, PE,期刊：Journal of clinical investigation, 页码：1119-1129 , 文章类型： Article，,卷期：2011年121-3]
- Malaria caused by Plasmodium falciparum results in approximately 1 million annual deaths worldwide, with young children and pregnant mothers at highest risk. Disease severity might be related to parasite virulence factor...
- Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice
[作者：Ballon, G; Chen, K; Perez, R; Tam, W; Cesarman, E,期刊：Journal of clinical investigation, 页码：1141-1153 , 文章类型： Article，,卷期：2011年121-3]
- Kaposi sarcoma herpesvirus (KSHV) is specifically associated with Kaposi sarcoma (KS) and 2 B cell lympho-proliferative diseases, namely primary effusion lymphoma (PEL) and multicentric Castleman disease (MCD). KS, PEL, ...
- IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B
[作者：Publicover, J; Goodsell, A; Nishimura, S; Vilarinho, S; Wang, ZE; Avanesyan, L; Spolski, R; Leonard, WJ; Cooper, S; Baron, JL,期刊：Journal of clinical investigation, 页码：1154-1162 , 文章类型： Article，,卷期：2011年121-3]
- HBV is a noncytopathic hepadnavirus and major human pathogen that causes immune-mediated acute and chronic hepatitis. The immune response to HBV antigens is age dependent: viral clearance occurs in most adults, while neo...
- Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells
[作者：Lukasova, M; Malaval, C; Gille, A; Kero, J; Offermanns, S,期刊：Journal of clinical investigation, 页码：1163-1173 , 文章类型： Article，,卷期：2011年121-3]
- Nicotinic acid (niacin) is a drug used to reduce the progression of atherosclerosis. Its antiatherosclerotic activity is believed to result from lipid-modifying effects, including its ability to decrease LDL cholesterol ...
- The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region
[作者：Herrero, R; Kajikawa, O; Matute-Bello, G; Wang, Y; Hagimoto, N; Mongovin, S; Wong, V; Park, DR; Brot, N; Heinecke, JW; Rosen, H; Goodman, RB; Fu, XY; Martin, TR,期刊：Journal of clinical investigation, 页码：1174-1190 , 文章类型： Article，,卷期：2011年121-3]
- Acute lung injury (ALI) is a life-threatening condition in critically ill patients. Injury to the alveolar epithelium is a critical event in ALI, and accumulating evidence suggests that it is linked to proapoptotic Fas/F...
- A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children
[作者：Duggal, P; Guo, XT; Haque, R; Peterson, KM; Ricklefs, S; Mondal, D; Alam, F; Noor, Z; Verkerke, HP; Marie, C; Leduc, CA; Chua, SC; Myers, MG; Leibel, RL; Houpt, E; Gilchrist, CA; Sher, A; Porcella, SF; Petri, WA,期刊：Journal of clinical investigation, 页码：1191-1198 , 文章类型： Article，,卷期：2011年121-3]
- Malnutrition substantially increases susceptibility to Entamoeba histolytica in children. Leptin is a hormone produced by adipocytes that inhibits food intake, influences the immune system, and is suppressed in malnouris...
- GLI3 repressor controls functional development of the mouse ureter
[作者：Cain, JE; Islam, E; Haxho, F; Blake, J; Rosenblum, ND,期刊：Journal of clinical investigation, 页码：1199-1206 , 文章类型： Article，,卷期：2011年121-3]
- Obstructive and nonobstructive forms of hydronephrosis (increased diameter of the renal pelvis and calyces) and hydroureter (dilatation of the ureter) are the most frequently detected antenatal abnormalities, yet the und...
- Food allergy
[作者：Wang, J; Sampson, HA,期刊：Journal of clinical investigation, 页码：827-835 , 文章类型： Article，,卷期：2011年121-3]
- Food allergies affect up to 6% of young children and 3%-4% of adults. They encompass a range of disorders that may be IgE and/or non-IgE mediated, including anaphylaxis, pollen food syndrome, food-protein-induced enteroc...
- Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
[作者：Varnum-Finney, B; Halasz, LM; Sun, MY; Gridley, T; Radtke, F; Bernstein, ID,期刊：Journal of clinical investigation, 页码：1207-1216 , 文章类型： Article，,卷期：2011年121-3]
- HSCs either self-renew or differentiate to give rise to multipotent cells whose progeny provide blood cell precursors. However, surprisingly little is known about the factors that regulate this choice of self-renewal ver...
- Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells
[作者：Narsinh, KH; Sun, N; Sanchez-Freire, V; Lee, AS; Almeida, P; Hu, SJ; Jan, T; Wilson, KD; Leong, D; Rosenberg, J; Yao, M; Robbins, RC; Wu, JC,期刊：Journal of clinical investigation, 页码：1217-1221 , 文章类型： Article，,卷期：2011年121-3]
- Human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) are promising candidate cell sources for regenerative medicine. However, despite the common ability of hiPSCs and hESCs to differentiat...
- Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity (vol 121, pg 396, 2011)
[作者：Corbin, AS; Agarwal, A; Loriaux, M; Cortes, J; Deininger, MW; Druker, BJ,期刊：Journal of clinical investigation, 页码：1222-1222 , 文章类型： Correction，,卷期：2011年121-3]
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