- Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation
[作者：Moraes, RC; Chang, H; Harrington, N; Landua, JD; Prigge, JT; Lane, TF; Wainwright, BJ; Hamel, PA; Lewis, MT,期刊：Development, 页码：1423-1432 , 文章类型： Article，,卷期：2009年136-9]
- Systemic hormones and local growth factor-mediated tissue interactions are essential for mammary gland development. Using phenotypic and transplantation analyses of mice carrying the mesenchymal dysplasia (mes) allele of...
- C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV
[作者：Kawano, T; Zheng, H; Merz, DC; Kohara, Y; Tamai, KK; Nishiwaki, K; Culotti, JG,期刊：Development, 页码：1433-1442 , 文章类型： Article，,卷期：2009年136-9]
- The gonad arms of C. elegans hermaphrodites acquire invariant shapes by guided migrations of distal tip cells (DTCs), which occur in three phases that differ in the direction and basement membrane substrata used for move...
- Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects
[作者：Hu, BY; Du, ZW; Li, XJ; Ayala, M; Zhang, SC,期刊：Development, 页码：1443-1452 , 文章类型： Article，,卷期：2009年136-9]
- Human embryonic stem cells (hESCs) offer a platform to bridge what we have learned from animal studies to human biology. Using oligodendrocyte differentiation as a model system, we show that sonic hedgehog (SHH)-dependen...
- Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11
[作者：Kawauchi, S; Kim, J; Santos, R; Wu, HH; Lander, AD; Calof, AL,期刊：Development, 页码：1453-1464 , 文章类型： Article，,卷期：2009年136-9]
- Foxg1, a winged-helix transcription factor, promotes the development of anterior neural structures; in mice lacking Foxg1, development of the cerebral hemispheres and olfactory epithelium (OE) is severely reduced. It has...
- Common genetic control of haemangioblast and cardiac development in zebrafish
[作者：Peterkin, T; Gibson, A; Patient, R,期刊：Development, 页码：1465-1474 , 文章类型： Article，,卷期：2009年136-9]
- Over the past few years it has become clear that over half of the mammalian heart derives from outside the heart field as originally defined. Such a second heart field, however, has not been described in zebrafish, which...
- The APC/C E3 ligase remains active in most post-mitotic Arabidopsis cells and is required for proper vasculature development and organization
[作者：Marrocco, K; Thomann, A; Parmentier, Y; Genschik, P; Criqui, MC,期刊：Development, 页码：1475-1485 , 文章类型： Article，,卷期：2009年136-9]
- Selective protein degradation via the ubiquitin-26S proteasome is a major mechanism underlying DNA replication and cell division in all eukaryotes. In particular, the APC/C (anaphase promoting complex or cyclosome) is a ...
- Functional diversity of R3 single-repeat genes in trichome development
[作者：Wester, K; Digiuni, S; Geier, F; Timmer, J; Fleck, C; Hulskamp, M,期刊：Development, 页码：1487-1496 , 文章类型： Article，,卷期：2009年136-9]
- Trichome and root hair patterning are governed by a conserved cassette of bHLH and MYB factors, the WD40 protein TTG1, and six single-repeat MYB R3 factors that are thought to counteract them. In this work we focus on th...
- Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells
[作者：Yu, JY; Reynolds, SH; Hatfield, SD; Shcherbata, HR; Fischer, KA; Ward, EJ; Long, D; Ding, Y; Ruohola-Baker, H,期刊：Development, 页码：1497-1507 , 文章类型： Article，,卷期：2009年136-9]
- It is important to understand the regulation of stem cell division because defects in this process can cause altered tissue homeostasis or cancer. The cyclin-dependent kinase inhibitor Dacapo (Dap), a p21/p27 homolog, ac...
- A gain-of-function mutation in IAA18 alters Arabidopsis embryonic apical patterning
[作者：Ploense, SE; Wu, MF; Nagpal, P; Reed, JW,期刊：Development, 页码：1509-1517 , 文章类型： Article，,卷期：2009年136-9]
- Lateral organ emergence in plant embryos and meristems depends on spatially coordinated auxin transport and auxin response. Here, we report the gain-of-function iaa18-1 mutation in Arabidopsis, which stabilizes the Aux/I...
- Fate mapping of mammalian embryonic taste bud progenitors
[作者：Thirumangalathu, S; Harlow, DE; Driskell, AL; Krimm, RF; Barlow, LA,期刊：Development, 页码：1519-1528 , 文章类型： Article，,卷期：2009年136-9]
- Mammalian taste buds have properties of both epithelial and neuronal cells, and are thus developmentally intriguing. Taste buds differentiate at birth within epithelial appendages, termed taste papillae, which arise at m...
- Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants
[作者：Naramoto, S; Sawa, S; Koizumi, K; Uemura, T; Ueda, T; Friml, J; Nakano, A; Fukuda, H,期刊：Development, 页码：1529-1538 , 文章类型： Article，,卷期：2009年136-9]
- ACAP-type ARF GTPase activating proteins (ARF-GAPs) regulate multiple cellular processes, including endocytosis, secretion, phagocytosis, cell adhesion and cell migration. However, the regulation of ACAP functions by oth...
- The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus
[作者：Jorgensen, P; Steen, JAJ; Steen, H; Kirschner, MW,期刊：Development, 页码：1539-1548 , 文章类型： Article，,卷期：2009年136-9]
- Little is known about how metabolism changes during development. For most animal embryos, yolk protein is a principal source of nutrition, particularly of essential amino acids. Within eggs, yolk is stored inside large o...
- Drosophila Tubulin-specific chaperone E functions at neuromuscular synapses and is required for microtubule network formation
[作者：Jin, S; Pan, LY; Liu, ZH; Wang, QF; Xu, ZH; Zhang, YQ,期刊：Development, 页码：1571-1581 , 文章类型： Article，,卷期：2009年136-9]
- Hypoparathyroidism, mental retardation and facial dysmorphism (HRD) is a fatal developmental disease caused by mutations in tubulin-specific chaperone E (TBCE). A mouse Tbce mutation causes progressive motor neuronopathy...
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