- Increased Expression of Macrophage Migration Inhibitory Factor During Progression to Hypopharyngeal Squamous Cell Carcinoma
[作者:Cludts, S; Decaestecker, C; Johnson, B; Lechien, J; Leroy, X; Kindt, N; Kaltner, H; Andre, S; Gabius, HJ; Saussez, S,期刊:Anticancer Research, 页码:3313-3319 , 文章类型: Article,,卷期:2010年30-9]
- Background/Aim: To examine the presence of macrophage migration inhibitory factor (MIF) quantitatively in relation to neoplastic progression of hypopharyngeal squamous cell carcinoma (HSCC). Materials and Methods: The pr...
- Efficacy of MDM2 Inhibitor MI-219 Against Lung Cancer Cells Alone or in Combination with MDM2 Knockdown, a XIAP Inhibitor or Etoposide
[作者:Zheng, M; Yang, J; Xu, XA; Sebolt, JT; Wang, SM; Sun, Y,期刊:Anticancer Research, 页码:3321-3331 , 文章类型: Article,,卷期:2010年30-9]
- The p53 tumor suppressor is negatively regulated by murine double minute 2 (MDM2), which binds to p53 and promotes p53 ubiquitination and degradation. MDM2 inhibitor-219 (MI-219), a small molecule MDM2 inhibitor, was rec...
- Synergistic Cytotoxic Effects of Arsenic Trioxide plus Dithiothreitol on Mice Oral Cancer Cells
[作者:Tsai, CW; Chang, NW; Tsai, RY; Wang, RF; Hsu, CM; Lin, SS; Wu, CN; Sun, SS; Tsai, MH; Bau, DT,期刊:Anticancer Research, 页码:3655-3660 , 文章类型: Article,,卷期:2010年30-9]
- The anti-tumor properties of arsenic trioxide have attracted extensive attention after successfully inducing apoptosis of acute promyelocytic leukemia cells. However, the therapeutic spectrum should not only be restricte...
- The Presence of P-glycoprotein in L1210 Cells Directly Induces Down-Regulation of Cell Surface Saccharide Targets of Concanavalin A
[作者:Sulova, Z; Ditte, P; Kurucova, T; Polakova, E; Rogozanova, K; Gibalova, L; Seres, M; Skvarkova, L; Sedlak, J; Pastorek, J; Breier, A,期刊:Anticancer Research, 页码:3661-3668 , 文章类型: Article,,卷期:2010年30-9]
- Overexpression of P-glycoprotein (P-gp), a plasma membrane drug transporter (ABCB1, a member of the ABC transporter family), is the most prevalent cause of multidrug resistance in cancer tissues. Lectin concanavalin A (C...
- Growth Inhibitory and Apoptosis-inducing Effects of Xanthohumol, a Prenylated Chalone Present in Hops, in Human Prostate Cancer Cells
[作者:Deeb, D; Gao, X; Jiang, H; Arbab, AS; Dulchavsky, SA; Gautam, SC,期刊:Anticancer Research, 页码:3333-3339 , 文章类型: Article,,卷期:2010年30-9]
- Promotion of apoptosis in cancer cells could potentially lead to the regression and improved prognosis of hormone-refractory prostate cancer. Xanthohumol (XN), a prenylated chalcone-derived from hops, has shown strong an...
- Effect of a Neurokinin-1 Receptor Antagonist in a Rat Model of Colitis-Associated Colon Cancer
[作者:Pagan, B; Isidro, AA; Coppola, D; Chen, ZM; Ren, YA; Wu, J; Appleyard, CB,期刊:Anticancer Research, 页码:3345-3353 , 文章类型: Article,,卷期:2010年30-9]
- Aim: The role of substance P and the neurokinin-1 receptor (NK-1R) in the transition from inflammation to dysplasia in inflammatory bowel disease is not clear. Materials and Methods: Colitis-associated dysplasia was indu...
- Active Surveillance for Low-risk Prostate Cancer
[作者:Mazzucchelli, R; Nesseris, I; Cheng, LA; Lopez-Beltran, A; Montironi, R; Scarpelli, M,期刊:Anticancer Research, 页码:3683-3692 , 文章类型: Review,,卷期:2010年30-9]
- Surgery, and radiation therapy remain the standard treatments for newly diagnosed prostate cancer patients. Nonetheless, these aggressive treatments are associated with decreased quality of life with altered sexual and u...
- Sunitinib (SU11248) Inhibits Growth of Human Ovarian Cancer in Xenografted Mice
[作者:Bauerschlag, DO; Schem, C; Tiwari, S; Egberts, JH; Weigel, MT; Kalthoff, H; Jonat, W; Maass, N; Meinhold-Heerlein, I,期刊:Anticancer Research, 页码:3355-3360 , 文章类型: Article,,卷期:2010年30-9]
- Background: Treatment of ovarian cancer is still challenging especially in recurrent platinum refractory cases. Sunitinib is a multi tyrosine kinase inhibitor targeting receptors for vascular endothelial growth factor an...
- Identification of Up- and Down-regulated Proteins in Gemcitabine-resistant Pancreatic Cancer Cells Using Two-dimensional Gel Electrophoresis and Mass Spectrometry
[作者:Kuramitsu, Y; Taba, K; Ryozawa, S; Yoshida, K; Zhang, XL; Tanaka, T; Maehara, SI; Maehara, Y; Sakaida, I; Nakamura, K,期刊:Anticancer Research, 页码:3367-3372 , 文章类型: Article,,卷期:2010年30-9]
- The prognosis of patients with pancreatic cancer is very poor because of late diagnosis and the lack of response to various therapies. Pancreatic cancer is generally resistant to chemotherapy and is highly fatal. Gemcita...
- p27(kiP1) Expression in Non-small Cell Lung Cancer Is not an Independent Prognostic Factor
[作者:Sion-Vardy, N; Freedman, J; Lazarov, I; Bolotin, A; Ariad, S,期刊:Anticancer Research, 页码:3699-3704 , 文章类型: Article,,卷期:2010年30-9]
- Background: p27(Kip1)( (p27) plays an important role in cancer cell cycle regulation. Recent evidence however, suggests that p27 may function as an oncogene rather than a tumour suppressor gene. Patients and Methods: Nin...
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