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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共31条记录   Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways [作者：Deng, JY; Hsieh, PS; Huang, JP; Lu, LS; Hung, LM,期刊：Diabetes, 页码：1814-1823 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Estradiol (E,) is known to modulate insulin sensitivity and, consequently, glucose homeostasis. Resveratrol (RSV), an agonist of estrogen receptor (ER), has exerted antihyperglycemic effects in streptozotocin-i... Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism [作者：Qiao, LP; Zou, CH; van der Westhuyzen, DR; Shao, JH,期刊：Diabetes, 页码：1824-1833 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Adiponectin is an adipocyte-derived hormone that plays an important role in glucose and lipid metabolism. The main aims of this study are to investigate the effects of adiponectin on VLDL triglyceride (VLDL-TG)... Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects - Effect of beta-adrenergic stimulation [作者：Jocken, JWE; Roepstorff, C; Goossens, GH; van der Baan, P; van Baak, M; Saris, WHM; Kiens, B; Blaak, EE,期刊：Diabetes, 页码：1834-1841 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Increased intramuscular triacylglycerol (IMTG) storage is a characteristic of the obese insulin-resistant state. We aimed to investigate whether a blunted fasting or beta-adrenergically mediated lipolysis contr... Protective role of programmed death 1 ligand 1 (PD-L1) in nonobese diabetic mice - The paradox in transgenic models [作者：Wang, CJ; Chou, FC; Chu, CH; Wu, JC; Lin, SH; Chang, DM; Sytwu, HK,期刊：Diabetes, 页码：1861-1869 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Coinhibitory signals mediated via programmed death 1 (PD-1) receptor play a critical role in downregulating immune responses and in maintaining peripheral tolerance. Programmed death 1 ligand 1 (PD-L1), the int... Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets [作者：Olerud, J; Johansson, M; Lawler, J; Welsh, N; Carlsson, PO,期刊：Diabetes, 页码：1870-1877 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Insufficient development of a new intra-islet capillary network after transplantation may be one contributing factor to the failure of islet grafts in clinical transplantation. The present study tested the hypo... Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice [作者：Vlad, G; D'Agati, VD; Zhang, QY; Liu, ZR; Ho, EK; Mohanakumar, T; Hardy, MA; Cortesini, R; Suciu-Foca, N,期刊：Diabetes, 页码：1878-1886 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-The aim of our study was to explore the immunomodulatory activity of soluble inummoglobulin (Ig)-like transcript (ILT) 3-Fc in pancreatic islet transplantation and to determine its mechanism of action.RESEARCH ... Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion - A new mechanism for fat-induced impairment of beta-cell function [作者：Kebede, M; Favaloro, J; Gunton, JE; Laybutt, DR; Shaw, M; Wong, N; Fam, BC; Aston-Mourney, K; Rantzau, C; Zulli, A; Proietto, J; Andrikopoulos, S,期刊：Diabetes, 页码：1887-1895 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Fructose-1,6-bisphosphatase (FBPase) is a gluconeogenic enzyme that is upregulated in islets or pancreatic beta-cell lines exposed to high fat. However, whether specific beta-cell upregulation of FBPase can imp... MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappa B activation in human pancreatic islet cells [作者：Mokhtari, D; Myers, JW; Welsh, N,期刊：Diabetes, 页码：1896-1904 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-The transcription factor nuclear factor-kappa B (NF-kappa B) and the mitogen-activated protein kinases (MAPKs) c-Jun NH2-terminal kinase (JNK) 1/2 are known to play decisive roles in cytokine-induced damage of ... Effect of oral amino acids on counterregulatory responses and cognitive function during insulin-induced hypoglycemia in nondiabetic and type 1 diabetic people [作者：Rossetti, P; Porcellati, F; Ricci, NB; Candeloro, P; Cioli, P; Nair, KS; Santeusanio, F; Bolli, GB; Fanelli, CG,期刊：Diabetes, 页码：1905-1917 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Amino acids stimulate glucagon responses to hypoglycemia and may be utilized by the brain. The aim of this study was to assess the responses to hypoglycemia in nondiabetic and type 1 diabetic subjects after ing... Circulating retinol-binding protein-4 concentration might reflect insulin resistance-associated iron overload [作者：Fernandez-Real, JM; Moreno, JM; Ricart, W,期刊：Diabetes, 页码：1918-1925 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVES-The mechanisms behind the association between retinol-binding protein-4 (RBP4) and insulin resistance are not well understood. An interaction between iron and vitamin A status, of which RBP4 is a surrogate, ha... Protein engineering strategies for sustained glucagon-like peptide-1 receptor-dependent control of glucose homeostasis [作者：Picha, KM; Cunningham, MR; Drucker, DJ; Mathur, A; Ort, T; Scully, M; Soderman, A; Spinka-Doms, T; Stojanovic-Susulic, V; Thomas, BA; O'Neil, KT,期刊：Diabetes, 页码：1926-1934 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-We have developed a novel platform for display and delivery of bioactive peptides that links the biological properties of the peptide to the pharmacokinetic properties of an antibody. Peptides engineered in the... RAGE and modulation of ischemic injury in the diabetic myocardium [作者：Bucciarelli, LG; Ananthakrishnan, R; Hwang, YC; Kaneko, M; Soling, F; Sell, DR; Strauch, C; Monnier, VM; Yan, SF; Schmidt, AM; Ramasamy, R,期刊：Diabetes, 页码：1941-1951 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Subjects with diabetes experience an increased risk of myocardial infarction and cardiac failure compared with nondiabetic age-matched individuals. The receptor for advanced glycation end products (RAGE) is upr... Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators [作者：Busik, JV; Mohr, S; Grant, MB,期刊：Diabetes, 页码：1952-1965 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-This study determined the effects of high glucose exposure and cytokine treatment on generation of reactive oxygen species (ROS) and activation of inflammatory and apoptotic pathways in human retinal endothelia... Blockade of alpha 4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity [作者：Feral, CC; Neels, JG; Kummer, C; Slepak, M; Olefsky, JM; Ginsberg, MH,期刊：Diabetes, 页码：1842-1851 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Many prevalent diseases of advanced societies, such as obesity-induced type 2 diabetes, are linked to indolent mononuclear cell-dependent inflammation. We previously proposed that blockade of alpha 4 integrin s... Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice [作者：Levisetti, MG; Lewis, DM; Suri, A; Unanue, ER,期刊：Diabetes, 页码：1852-1860 , 文章类型： Article，,卷期：2008年57-7] OBJECTIVE-Weak major histocompatibility complex (MHC) binding of self-peptides has been proposed as a mechanism that may contribute to autoimmunity by allowing for escape of autoreactive T-cells from the thymus. We exami... Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes [作者：James, EA; Kwok, WW,期刊：Diabetes, 页码：1788-1789 , 文章类型： Editorial Material，,卷期：2008年57-7]