- UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity
[作者:Achour, M; Fuhrmann, G; Alhosin, M; Ronde, P; Chataigneau, T; Mousli, M; Schini-Kerth, VB; Bronner, C,期刊:Biochemical and Biophysical Research Communications, 页码:523-528 , 文章类型: Article,,卷期:2009年390-3]
- Tat-interactive protein, 60 kDa (Tip60) is a histone acetyltransferase with specificity toward lysine 5 of histone H2A (H2AK5) and plays Multiple roles in chromatin remodeling processes. Co-immunoprecipitation experiment...
- Regulation of AHI1 expression in adult rat brain: Implication in hypothalamic feeding control
[作者:Han, SB; Choi, BI; Lee, D; Kee, SH; Kim, HS; Sun, W; Kim, H,期刊:Biochemical and Biophysical Research Communications, 页码:535-540 , 文章类型: Article,,卷期:2009年390-3]
- Recent studies revealed that Abelson helper integration site I (AHI1) plays a role in brain development. However, little is known about the role of AHI1 in adult brain. To directly assess the role of AHI1 in the adult br...
- R-spondin1 is required for normal epithelial morphogenesis during mammary gland development
[作者:Chadi, S; Buscara, L; Pechoux, C; Costa, J; Laubier, J; Chaboissier, MC; Pailhoux, E; Vilotte, JL; Chanat, E; Le Provost, F,期刊:Biochemical and Biophysical Research Communications, 页码:1040-1043 , 文章类型: Article,,卷期:2009年390-3]
- The R-spondin (Rspo) proteins constitute a novel class of ligands that induce Wnt signalling. Rspo1 knockout XX mice were previously shown to be sex-reversed, but some remain sub-fertile. These last were unable to feed t...
- Heme-induced Trypanosoma cruzi proliferation is mediated by CaM kinase II
[作者:Souza, CF; Carneiro, AB; Silveira, AB; Laranja, GAT; Silva-Neto, MAC; da Costa, SCG; Paes, MC,期刊:Biochemical and Biophysical Research Communications, 页码:541-546 , 文章类型: Article,,卷期:2009年390-3]
- Trypanosoma cruzi, the etiologic agent of Chagas disease, is transmitted through triatomine vectors during their blood-meal on vertebrate hosts. These hematophagous insects usually ingest approximately 10 mM of heme boun...
- A monoclonal antibody IMab-1 specifically recognizes IDH1(R132H), the most common glioma-derived mutation
[作者:Kato, Y; Jin, GL; Kuan, CT; McLendon, RE; Yan, H; Bigner, DD,期刊:Biochemical and Biophysical Research Communications, 页码:547-551 , 文章类型: Article,,卷期:2009年390-3]
- IDH1 (isocitrate dehydrogenase 1) mutations have been identified as early and frequent genetic alterations in astrocytomas, oligodendrogliomas, and oligoastrocytomas as well as secondary glioblastomas. In contrast, prima...
- Independent stabilizations of polysomal Drg1/Dfrp1 complex and non-polysomal Drg2/Dfrp2 complex in mammalian cells
[作者:Ishikawa, K; Akiyama, T; Ito, K; Semba, K; Inoue, J,期刊:Biochemical and Biophysical Research Communications, 页码:552-556 , 文章类型: Article,,卷期:2009年390-3]
- Various widely known GTPases are associated with diverse crucial cellular processes. However, the functional targets of the universally conserved homologous GTPases Drg1 and Drg2, constituting the DRG subfamily in eukary...
- Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents
[作者:Arakawa, M; Ebato, C; Mita, T; Hirose, T; Kawamori, R; Fujitani, Y; Watada, H,期刊:Biochemical and Biophysical Research Communications, 页码:809-814 , 文章类型: Article,,卷期:2009年390-3]
- Beta-cell proliferation is regulated by various metabolic demands including peripheral insulin resistance, obesity, and hyperglycemia. In addition to enhancement of glucose-induced insulin secretion, agonists for glucago...
- The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting
[作者:Nakashima, Y; Ono, K; Yoshida, Y; Kojima, Y; Kita, T; Tanaka, M; Kimura, T,期刊:Biochemical and Biophysical Research Communications, 页码:821-826 , 文章类型: Article,,卷期:2009年390-3]
- Cardiac transcription factors play crucial roles in cardiac development and differentiation. To address the target genes they regulate is important for understanding the molecular mechanisms underlying these processes. I...
- Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly
[作者:Tannukit, S; Crabb, TL; Hertel, KJ; Wen, X; Jans, DA; Paine, ML,期刊:Biochemical and Biophysical Research Communications, 页码:1044-1050 , 文章类型: Article,,卷期:2009年390-3]
- Tuftelin-interacting protein 11 (TFIP11) is a protein component of the spliceosome complex that promotes the release of the lariat-intron during late-stage splicing through a direct recruitment and interaction with DHX15...
- Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling
[作者:Miyake, A; Takahashi, Y; Miwa, H; Shimada, A; Konishi, M; Itoh, N,期刊:Biochemical and Biophysical Research Communications, 页码:1051-1055 , 文章类型: Article,,卷期:2009年390-3]
- A gene encoding a novel secreted protein in mice and humans was identified, and named Neucrin. Mouse Neucrin consists of 343 amino acids with a cysteine-rich domain in its carboxyl terminal region. The positions of 10 cy...
- Antibody-mediated synergy and interference in the neutralization of SARS-CoV at an epitope cluster on the spike protein
[作者:Zhong, L; Haynes, L; Struble, EB; Tamin, A; Virata-Theimer, ML; Zhang, P,期刊:Biochemical and Biophysical Research Communications, 页码:1056-1060 , 文章类型: Article,,卷期:2009年390-3]
- Incomplete neutralization of virus, especially when it occurs in the presence of excess neutralizing antibody, represents a biological phenomenon that impacts greatly on antibody-mediated immune prophylaxis of viral infe...
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