- Crucial Role of the Central Leptin Receptor in Murine Trypanosoma cruzi (Brazil Strain) Infection
[作者:Nagajyothi, F; Zhao, DZ; Machado, FS; Weiss, LM; Schwartz, GJ; Desruisseaux, MS; Zhao, Y; Factor, SM; Huang, H; Albanese, C; Teixeira, MM; Scherer, PE; Chua, SC; Tanowitz, HB,期刊:Journal of Infectious Diseases, 页码:1104-1113 , 文章类型: Article,,卷期:2010年202-7]
- Mice carrying a defective leptin receptor gene (db/db mice) are metabolically challenged and upon infection with Trypanosoma cruzi (Brazil strain) suffer high mortality. In genetically modified db/db mice, (NSE-Rb db/db ...
- A Randomized Clinical Trial Comparing Revaccination with Pneumococcal Conjugate Vaccine to Polysaccharide Vaccine among HIV-Infected Adults
[作者:Crum-Cianflone, NF; Hullsiek, KH; Roediger, M; Ganesan, A; Patel, S; Landrum, ML; Weintrob, A; Agan, BK; Medina, S; Rahkola, J; Hale, BR; Janoff, EN,期刊:Journal of Infectious Diseases, 页码:1114-1125 , 文章类型: Article,,卷期:2010年202-7]
- Background. The risk of pneumococcal disease persists, and antibody responses to revaccination with the 23-valent polysaccharide vaccine (PPV) are low among human immunodeficiency virus (HIV)-infected adults. We determin...
- Kaposi Sarcoma (KS)-Associated Herpesvirus MicroRNA Sequence Analysis and KS Risk in a European AIDS-KS Case Control Study
[作者:Marshall, V; Martro, E; Labo, N; Ray, A; Wang, DA; Mbisa, G; Bagni, RK; Volfovsky, N; Casabona, J; Whitby, D,期刊:Journal of Infectious Diseases, 页码:1126-1135 , 文章类型: Article,,卷期:2010年202-7]
- Background. We recently identified polymorphisms in Kaposi sarcoma-associated herpesvirus (KSHV)-encoded microRNA (miRNA) sequences from clinical subjects. Here, we examine whether any of these may contribute to KS risk ...
- Influenza Virus-Cytokine-Protease Cycle in the Pathogenesis of Vascular Hyperpermeability in Severe Influenza
[作者:Wang, SY; Le, TQ; Kurihara, N; Chida, J; Cisse, Y; Yano, M; Kido, H,期刊:Journal of Infectious Diseases, 页码:991-1001 , 文章类型: Article,,卷期:2010年202-7]
- Background. Severe influenza is characterized by cytokine storm and multiorgan failure with edema. The aim of this study was to define the impact of the cytokine storm on the pathogenesis of vascular hyperpermeability in...
- Inferring the Serotype Associated with Dengue Virus Infections on the Basis of Pre- and Postinfection Neutralizing Antibody Titers
[作者:van Panhuis, WG; Gibbons, RV; Endy, TP; Rothman, AL; Srikiatkhachorn, A; Nisalak, A; Burke, DS; Cummings, DAT,期刊:Journal of Infectious Diseases, 页码:1002-1010 , 文章类型: Article,,卷期:2010年202-7]
- Background. Currently, the only tests capable of determining the serotype associated with dengue virus (DENV) infection require sampling during the period of acute viremia. No test can accurately detect the serotype asso...
- Multiple Infections with Seasonal Influenza A Virus Induce Cross-Protective Immunity against A(H1N1) Pandemic Influenza Virus in a Ferret Model
[作者:Laurie, KL; Carolan, LA; Middleton, D; Lowther, S; Kelso, A; Barr, IG,期刊:Journal of Infectious Diseases, 页码:1011-1020 , 文章类型: Article,,卷期:2010年202-7]
- Background. An age bias toward children and young adults has been reported for infection and hospitalizations with pandemic H1N1 influenza (A[H1N1]pdm) in the 2009 and 2010 influenza seasons in the Southern and Northern ...
- Helicobacter pylori-Induced Loss of the Inhibitor-of-Apoptosis Protein Survivin Is Linked to Gastritis and Death of Human Gastric Cells
[作者:Valenzuela, M; Perez-Perez, G; Corvalan, AH; Carrasco, G; Urra, H; Bravo, D; Toledo, H; Quest, AFG,期刊:Journal of Infectious Diseases, 页码:1021-1030 , 文章类型: Article,,卷期:2010年202-7]
- Helicobacter pylori infects the human stomach and modifies signaling pathways that affect gastric epithelial cell proliferation and viability. Chronic exposure to this pathogen contributes to the onset of gastric atrophy...
- Staphylococcus aureus Small-Colony Variants Are Adapted Phenotypes for Intracellular Persistence
[作者:Tuchscherr, L; Heitmann, V; Hussain, M; Viemann, D; Roth, J; von Eiff, C; Peters, G; Becker, K; Loffler, B,期刊:Journal of Infectious Diseases, 页码:1031-1040 , 文章类型: Article,,卷期:2010年202-7]
- Background. Staphylococcus aureus is an important human pathogen of endovascular diseases, which can take a chronic course with a high relapse rate despite antimicrobial treatment. Thus far, persistent and antibioticrefr...
- Activation of Plasminogen by Staphylokinase Reduces the Severity of Staphylococcus aureus Systemic Infection
[作者:Kwiecinski, J; Josefsson, E; Mitchell, J; Higgins, J; Magnusson, M; Foster, T; Jin, T; Bokarewa, M,期刊:Journal of Infectious Diseases, 页码:1041-1049 , 文章类型: Article,,卷期:2010年202-7]
- Background. Staphylokinase (SAK) is produced by the majority of Staphylococcus aureus strains. It is an extracellular protein that activates the conversion of human plasminogen (plg) to plasmin. The role played by SAK in...
- Targeting of Alpha-Hemolysin by Active or Passive Immunization Decreases Severity of USA300 Skin Infection in a Mouse Model
[作者:Kennedy, AD; Wardenburg, JB; Gardner, DJ; Long, D; Whitney, AR; Braughton, KR; Schneewind, O; DeLeo, FR,期刊:Journal of Infectious Diseases, 页码:1050-1058 , 文章类型: Article,,卷期:2010年202-7]
- Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are predominantly those affecting skin and soft tissues. Although progress has been made, our knowledge of the molecules that contribu...
- Priming the Immune System for Heart Disease: A Perspective on Group A Streptococci
[作者:Ellis, NMJ; Kurahara, DK; Vohra, H; Mascaro-Blanco, A; Erdem, G; Adderson, EE; Veasy, LG; Stoner, JA; Tam, E; Hill, HR; Yamaga, K; Cunningham, MW,期刊:Journal of Infectious Diseases, 页码:1059-1067 , 文章类型: Article,,卷期:2010年202-7]
- Although immune responses against group A streptococci and the heart have been correlated with antibodies and T cell responses against cardiac myosin, there is no unifying hypothesis about carditis caused globally by man...
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