- Hepatitis B Virus Kinetics under Antiviral Therapy Sheds Light on Differences in Hepatitis B e Antigen Positive and Negative Infections
[作者:Ribeiro, RM; Germanidis, G; Powers, KA; Pellegrin, B; Nikolaidis, P; Perelson, AS; Pawlotsky, JM,期刊:Journal of Infectious Diseases, 页码:1309-1318 , 文章类型: Article,,卷期:2010年202-9]
- Background. Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B infection has a presentation and clinical course that is divergent from that of HBeAg-positive infection. The former usually presents with lower vira...
- Effectiveness of Public Health Measures in Mitigating Pandemic Influenza Spread: A Prospective Sero-Epidemiological Cohort Study
[作者:Lee, VJ; Yap, J; Cook, AR; Chen, MI; Tay, JK; Barr, I; Kelso, A; Tan, BH; Loh, JP; Lin, R; Cui, L; Kelly, PM; Leo, YS; Chia, KS; Kang, WL; Tambyah, PA; Seet, B,期刊:Journal of Infectious Diseases, 页码:1319-1326 , 文章类型: Article,,卷期:2010年202-9]
- Background. Few studies have validated the effectiveness of public health interventions in reducing influenza spread in real-life settings. We aim to validate these measures used during the 2009 pandemic. Methods. From 2...
- A Single Dose of Unadjuvanted Novel 2009 H1N1 Vaccine Is Immunogenic and Well Tolerated in Young and Elderly Adults
[作者:Talaat, KR; Greenberg, ME; Lai, MH; Hartel, GF; Wichems, CH; Rockman, S; Jeanfreau, RJ; Ghosh, MR; Kabongo, ML; Gittleson, C; Karron, RA,期刊:Journal of Infectious Diseases, 页码:1327-1337 , 文章类型: Article,,卷期:2010年202-9]
- Background. When the novel H1N1 influenza A strain appeared in April of 2009, development of novel H1N1 vaccines became a public health priority. Methods. We conducted a phase-2, multicenter, randomized, placebo-controll...
- Effect on Virulence and Pathogenicity of H5N1 Influenza A Virus through Truncations of NS1 eIF4GI Binding Domain
[作者:Zhou, HB; Zhu, JP; Tu, JG; Zou, W; Hu, Y; Yu, ZJ; Yin, WS; Li, YT; Zhang, AD; Wu, YR; Yu, ZN; Chen, HC; Jin, ML,期刊:Journal of Infectious Diseases, 页码:1338-1346 , 文章类型: Article,,卷期:2010年202-9]
- To study the effect of NS1 eIF4GI binding domain on virulence and pathogenicity of H5N1 influenza A virus, 5 recombinant H5N1 viruses encoding eIF4GI binding domain-truncated NS1 proteins and parental NS1 (NS1-wt) were g...
- Sex and Geographic Patterns of Human Herpesvirus 8 Infection in a Nationally Representative Population-Based Sample in Uganda
[作者:Biryahwaho, B; Dollard, SC; Pfeiffer, RM; Shebl, FM; Munuo, S; Amin, MM; Hladik, W; Parsons, R; Mbulaiteye, SM,期刊:Journal of Infectious Diseases, 页码:1347-1353 , 文章类型: Article,,卷期:2010年202-9]
- Background. Human herpesvirus 8 (HHV8), the infectious cause of Kaposi sarcoma, varies dramatically across Africa, suggesting that cofactors correlated with large-area geographic or environmental characteristics may infl...
- West Nile Fever Characteristics among Viremic Persons Identified through Blood Donor Screening
[作者:Zou, SMA; Foster, GA; Dodd, RY; Petersen, LR; Stramer, SL,期刊:Journal of Infectious Diseases, 页码:1354-1361 , 文章类型: Article,,卷期:2010年202-9]
- Nucleic acid testing (NAT) of blood donors provides opportunities for identifying West Nile virus (WNV)-infected persons before symptoms develop and for characterizing subsequent illness. From June 2003 through 2008, the...
- Artemisinin-Induced Dormancy in Plasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure
[作者:Teuscher, F; Gatton, ML; Chen, NH; Peters, J; Kyle, DE; Cheng, Q,期刊:Journal of Infectious Diseases, 页码:1362-1368 , 文章类型: Article,,卷期:2010年202-9]
- Background. Despite the remarkable activity of artemisinin and its derivatives, monotherapy with these agents has been associated with high rates of recrudescence. The temporary arrest of the growth of ring-stage parasit...
- Schistosomal-Derived Lysophosphatidylcholine Are Involved in Eosinophil Activation and Recruitment through Toll-Like Receptor-2-Dependent Mechanisms
[作者:Magalhaes, KG; Almeida, PE; Atella, GC; Maya-Monteiro, CM; Castro-Faria-Neto, HC; Pelajo-Machado, M; Lenzi, HL; Bozza, MT; Bozza, PT,期刊:Journal of Infectious Diseases, 页码:1369-1379 , 文章类型: Article,,卷期:2010年202-9]
- Parasite-derived lipids may play important roles in host-pathogen interactions and escape mechanisms. Herein, we evaluated the role of schistosomal-derived lipids in Toll-like receptor (TLR)-2 and eosinophil activation i...
- Enhanced Molecular Typing of Treponema pallidum: Geographical Distribution of Strain Types and Association with Neurosyphilis
[作者:Marra, CM; Sahi, SK; Tantalo, LC; Godornes, C; Reid, T; Behets, F; Rompalo, A; Klausner, JD; Yin, YP; Mulcahy, F; Golden, MR; Centurion-Lara, A; Lukehart, SA,期刊:Journal of Infectious Diseases, 页码:1380-1388 , 文章类型: Article,,卷期:2010年202-9]
- Background. Strain typing is a tool for determining the diversity and epidemiology of infections. Methods. Treponema pallidum DNA was isolated from 158 patients with syphilis from the United States, China, Ireland, and M...
- CXCL16 Contributes to Neutrophil Recruitment to Cerebrospinal Fluid in Pneumococcal Meningitis
[作者:Woehrl, B; Klein, M; Rupprecht, TA; Schmetzer, H; Angele, B; Hacker, H; Hacker, G; Pfister, HW; Koedel, U,期刊:Journal of Infectious Diseases, 页码:1389-1396 , 文章类型: Article,,卷期:2010年202-9]
- In this study, we analyzed the expression and function of CXCL16 in pneumococcal meningitis. CXCL16 was found to be up-regulated in RAW264.7 macrophages (but not in neutrophils and endothelial cells) upon pneumococcal st...
- Transcriptome Analysis Indicates an Enhanced Activation of Adaptive and Innate Immunity by Chlamydia-Infected Murine Epithelial Cells Treated with Interferon gamma
[作者:Burian, K; Endresz, V; Deak, J; Kormanyos, Z; Pal, A; Nelson, D; Virok, DP,期刊:Journal of Infectious Diseases, 页码:1405-1414 , 文章类型: Article,,卷期:2010年202-9]
- Background. Interferon gamma (IFN-gamma) is the major cytokine involved in the elimination of Chlamydia infection. Despite its importance, the combined effect of Chlamydia infection and IFN-gamma on the gene expression o...
- Tissue Factor-Dependent Procoagulant Activity of Subtilase Cytotoxin, a Potent AB(5) Toxin Produced by Shiga Toxigenic Escherichia coli
[作者:Wang, H; Paton, JC; Thorpe, CM; Bonder, CS; Sun, WY; Paton, AW,期刊:Journal of Infectious Diseases, 页码:1415-1423 , 文章类型: Article,,卷期:2010年202-9]
- Subtilase cytotoxin (SubAB), produced by certain virulent Shiga toxigenic Escherichia coli strains, causes hemolytic uremic syndrome-like pathology in mice, including extensive microvascular thrombosis. SubAB acts by spe...
- Changes in Blood B Cell Phenotypes and Epstein-Barr Virus Load in Chronically Human Immunodeficiency Virus-Infected Patients before and after Antiretroviral Therapy
[作者:Richard, Y; Amiel, C; Jeantils, V; Mestivier, D; Portier, A; Dhello, G; Feuillard, J; Creidy, R; Nicolas, JC; Raphael, M,期刊:Journal of Infectious Diseases, 页码:1424-1434 , 文章类型: Article,,卷期:2010年202-9]
- Background. Switched and nonswitched memory B cells, which usually constitute the main reservoirs of Epstein-Barr virus (EBV), are rapidly depleted in patients with chronic human immunodeficiency virus (HIV) infection. B...
- Improved Prediction of HIV-1 Coreceptor Usage with Sequence Information from the Second Hypervariable Loop of gp120
[作者:Thielen, A; Sichtig, N; Kaiser, R; Lam, J; Harrigan, PR; Lengauer, T,期刊:Journal of Infectious Diseases, 页码:1435-1443 , 文章类型: Article,,卷期:2010年202-9]
- Background. Human immunodeficiency virus type 1 (HIV-1) uses the CD4 receptor and a coreceptor to gain cell entry. Coreceptor usage is mainly determined by the V3 loop of gp120. Therefore, coreceptor usage is currently i...
- Natural Killer Cells That Respond to Human Immunodeficiency Virus Type 1 (HIV-1) Peptides Are Associated with Control of HIV-1 Infection
[作者:Tiemessen, CT; Shalekoff, S; Meddows-Taylor, S; Schramm, DB; Papathanasopoulos, MA; Gray, GE; Sherman, GG; Coovadia, AH; Kuhn, L,期刊:Journal of Infectious Diseases, 页码:1444-1453 , 文章类型: Article,,卷期:2010年202-9]
- Human immunodeficiency virus (HIV)-specific natural killer (CD3(-) cells), CD4, and CD8 T cellular responses were determined in 79 HIV-1-infected women in response to HIV-1 peptide pools (Gag, Pol, Nef, Reg, and Env) wit...
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