- The New Species Brucella microti Replicates in Macrophages and Causes Death in Murine Models of Infection
[作者：de Bagues, MPJ; Ouahrani-Bettache, S; Quintana, JF; Mitjana, O; Hanna, N; Bessoles, S; Sanchez, F; Scholz, HC; Lafont, V; Kohler, S; Occhialini, A,期刊：Journal of Infectious Diseases, 页码：3-10 , 文章类型： Article，,卷期：2010年202-1]
- Background. The recent isolation of Brucella microti from the common vole, the red fox, and the soil raises the possibility of an eventual reemergence of brucellosis in Europe. In this work, the pathogenic potential of t...
- Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group A Streptococcus M1T1 Clone
[作者：Hollands, A; Pence, MA; Timmer, AM; Osvath, SR; Turnbull, L; Whitchurch, CB; Walker, MJ; Nizet, V,期刊：Journal of Infectious Diseases, 页码：11-19 , 文章类型： Article，,卷期：2010年202-1]
- Background. The recent resurgence of invasive group A streptococcal disease has been paralleled by the emergence of the M1T1 clone. Recently, invasive disease initiation has been linked to mutations in the covR/S 2-compo...
- Superantigen Genes Are More Important than the emm Type for the Invasiveness of Group A Streptococcus Infection
[作者：Lintges, M; van der Linden, M; Hilgers, RD; Arlt, S; Al-Lahham, A; Reinert, RR; Plucken, S; Rink, L,期刊：Journal of Infectious Diseases, 页码：20-28 , 文章类型： Article，,卷期：2010年202-1]
- Background. In this study, we examined the role of superantigen genes and emm genotypes of clinical Streptococcus pyogenes isolates collected in Germany between 1997 and 2003. Methods. Multiplex polymerase chain reaction...
- The Hepatitis C Virus (HCV) NS4B RNA Binding Inhibitor Clemizole Is Highly Synergistic with HCV Protease Inhibitors
[作者：Einav, S; Dvory-Sobol, H; Gehrig, E; Glenn, JS,期刊：Journal of Infectious Diseases, 页码：65-74 , 文章类型： Proceedings Paper，,卷期：2010年202-1]
- Background. We recently identified a compound, clemizole hydrochloride, that inhibits NS4B's RNA binding and hepatitis C virus (HCV) replication. Although significant, clemizole's antiviral effect is moderate (50% effect...
- La Protein Required for Internal Ribosome Entry Site-Directed Translation Is a Potential Therapeutic Target for Hepatitis C Virus Replication
[作者：Shirasaki, T; Honda, M; Mizuno, H; Shimakami, T; Okada, H; Sakai, Y; Murakami, S; Wakita, T; Kaneko, S,期刊：Journal of Infectious Diseases, 页码：75-85 , 文章类型： Article，,卷期：2010年202-1]
- Background. Translation of the hepatitis C virus (HCV) is mediated by an internal ribosome entry site (IRES). Here, we analyzed the functional relevance of La protein for replication of HCV using an infectious HCV clone,...
- HBsAg Profiles in Patients Receiving Peginterferon Alfa-2a plus Ribavirin for the Treatment of Dual Chronic Infection with Hepatitis B and C Viruses
[作者：Yu, ML; Lee, CM; Chuang, WL; Lu, SN; Dai, CY; Huang, JF; Lin, ZY; Hu, TH; Chen, CH; Hung, CH; Wang, JH; Chen, CL; Kao, JH; Lai, MY; Liu, CH; Su, TH; Wu, SS; Liao, LY; Kuo, HT; Chao, YC; Tung, SY; Yang, SS; Chen, PJ; Liu, CJ; Chen, DS,期刊：Journal of Infectious Diseases, 页码：86-92 , 文章类型： Proceedings Paper，,卷期：2010年202-1]
- Background. With use of peginterferon alfa-2a and ribavirin combination therapy in patients with dual chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, 11.2% of patients achieved clearance of hepatit...
- Molecular Epidemiology and Brief History of Emerging Adenovirus 14-Associated Respiratory Disease in the United States
[作者：Kajon, AE; Lu, XY; Erdman, DD; Louie, J; Schnurr, D; St George, K; Koopmans, MP; Allibhai, T; Metzgar, D,期刊：Journal of Infectious Diseases, 页码：93-103 , 文章类型： Article，,卷期：2010年202-1]
- Background. First isolated in the Netherlands in 1955 during an outbreak of acute respiratory disease (ARD) among military recruits, human adenovirus 14 (HAdV-14) has historically been considered rare. With no precedent ...
- Virologic Characterization of Multidrug-Resistant Cytomegalovirus Infection in 2 Transplant Recipients Treated with Maribavir
[作者：Strasfeld, L; Lee, I; Tatarowicz, W; Villano, S; Chou, SW,期刊：Journal of Infectious Diseases, 页码：104-108 , 文章类型： Proceedings Paper，,卷期：2010年202-1]
- The experimental cytomegalovirus UL97 kinase inhibitor maribavir was used to treat 2 cases of infection in which viral mutations that conferred ganciclovir and foscarnet resistance had evolved sequentially. In one case, ...
- Greater Endothelial Activation, Weibel-Palade Body Release and Host Inflammatory Response to Plasmodium vivax, Compared with Plasmodium falciparum: A Prospective Study in Papua, Indonesia
[作者：Yeo, TW; Lampah, DA; Tjitra, E; Piera, K; Gitawati, R; Kenangalem, E; Price, RN; Anstey, NM,期刊：Journal of Infectious Diseases, 页码：109-112 , 文章类型： Article，,卷期：2010年202-1]
- Pathogenic mechanisms underlying vivax malaria are poorly understood, with few studies comparing endothelial and inflammatory responses with falciparum malaria. In adults with uncomplicated vivax or falciparum malaria, w...
- Age-Related Susceptibility to Severe Malaria Associated with Galectin-2 in Highland Papuans
[作者：Randall, LM; Kenangalem, E; Lampah, DA; Tjitra, E; Mwaikambo, ED; Handojo, T; Piera, KA; Zhao, ZZ; Rivera, FD; Zhou, YH; McSweeney, KM; Le, L; Amante, FH; Haque, A; Stanley, AC; Woodberry, T; Salwati, E; Granger, DL; Hobbs, MR; Price, RN; Weinberg, JB; Montgomery, GW; Anstey, NM; Engwerda, CR,期刊：Journal of Infectious Diseases, 页码：117-124 , 文章类型： Article，,卷期：2010年202-1]
- Background. Age and host genetics are important determinants of malaria severity. Lymphotoxin-alpha (LT alpha) has been associated with the development of cerebral malaria (CM) and other severe malaria (SM) syndromes. Mu...
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