- A self-assembling hydrophobically modified chitosan capable of reversible hemostatic action
[作者:Dowling, MB; Kumar, R; Keibler, MA; Hess, JR; Bochicchio, GV; Raghavan, SR,期刊:BIOMATERIALS, 页码:3351-3357 , 文章类型: Article,,卷期:2011年32-13]
- Blood loss at the site of a wound in mammals is curtailed by the rapid formation of a hemostatic plug, i.e., a self-assembled network of the protein, fibrin that locally transforms liquid blood into a gelled clot. Here, ...
- Transparent, tough collagen laminates prepared by oriented flow casting, multi-cyclic vitrification and chemical cross-linking
[作者:Tanaka, Y; Baba, K; Duncan, TJ; Kubota, A; Asahi, T; Quantock, AJ; Yamato, M; Okano, T; Nishida, K,期刊:BIOMATERIALS, 页码:3358-3366 , 文章类型: Article,,卷期:2011年32-13]
- The lamellar architecture found in many natural fibrous tissues has a significant bearing on their specific functions. However, current engineered tissues have simultaneously no realistic structures and no adequate funct...
- The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
[作者:Xiao, K; Li, YP; Luo, JT; Lee, JS; Xiao, WW; Gonik, AM; Agarwal, RG; Lam, KS,期刊:BIOMATERIALS, 页码:3435-3446 , 文章类型: Article,,卷期:2011年32-13]
- To systematically elucidate the effect of surface charge on the cellular uptake and in vivo fate of PEG-oligocholic acid based micellar nanoparticles (NPs), the distal PEG termini of monomeric PEG-oligocholic acid dendri...
- Photosensitizer-conjugated magnetic nanoparticles for in vivo simultaneous magnetofluorescent imaging and targeting therapy
[作者:Huang, P; Li, ZM; Lin, J; Yang, DP; Gao, G; Xu, C; Bao, L; Zhang, CL; Wang, K; Song, H; Hu, HY; Cui, DX,期刊:BIOMATERIALS, 页码:3447-3458 , 文章类型: Article,,卷期:2011年32-13]
- A major challenge in nanotechnology and nanomedicine is to integrate tumor targeting, imaging, and selective therapy functions into a small single nanoparticle (<50 nm). Herein, photosensitizer-conjugated magnetic nanopa...
- The promotion of siRNA delivery to breast cancer overexpressing epidermal growth factor receptor through anti-EGFR antibody conjugation by immunoliposomes
[作者:Gao, J; Liu, W; Xia, Y; Li, W; Sun, J; Chen, HW; Li, BH; Zhang, DP; Qian, WZ; Meng, YC; Deng, L; Wang, H; Chen, JM; Guo, YJ,期刊:BIOMATERIALS, 页码:3459-3470 , 文章类型: Article,,卷期:2011年32-13]
- The LPD (liposome-polycation-DNA complex) is an effective nanovector for systemically small interfering RNA (siRNA) delivery which was well characterized previously. However, little effort was spend on the development of...
- Gene delivery system based on highly specific recognition of surface-vimentin with N-acetylglucosamine immobilized polyethylenimine
[作者:Kim, SJ; Ise, H; Goto, M; Komura, K; Cho, CS; Akaike, T,期刊:BIOMATERIALS, 页码:3471-3480 , 文章类型: Article,,卷期:2011年32-13]
- Gene and drug-delivery systems that use immobilization of carbohydrates are useful for the specific targeting of lectin-expressing tissues. Here, we report that N-acetylglucosamine (GlcNAc) with polyethylenimine (GlcNAc-...
- Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation
[作者:Pouponneau, P; Leroux, JC; Soulez, G; Gaboury, L; Martel, S,期刊:BIOMATERIALS, 页码:3481-3486 , 文章类型: Article,,卷期:2011年32-13]
- Magnetic tumor targeting with external magnets is a promising method to increase the delivery of cytotoxic agents to tumor cells while reducing side effects. However, this approach suffers from intrinsic limitations, suc...
- Tunable physiologic interactions of adhesion molecules for inflamed cell-selective drug delivery
[作者:Kang, S; Park, T; Chen, XY; Dickens, G; Lee, B; Lu, K; Rakhilin, N; Daniel, S; Jin, MM,期刊:BIOMATERIALS, 页码:3487-3498 , 文章类型: Article,,卷期:2011年32-13]
- Dysregulated inflammation contributes to the pathogenesis of various diseases. Therapeutic efficacy of anti-inflammatory agents, however, falls short against resilient inflammatory responses, whereas long-term and high-d...
- Hierarchical nanoengineered surfaces for enhanced cytoadhesion and drug delivery
[作者:Fischer, KE; Nagaraj, G; Daniels, RH; Li, E; Cowles, VE; Miller, JL; Bunger, MD; Desai, TA,期刊:BIOMATERIALS, 页码:3499-3506 , 文章类型: Article,,卷期:2011年32-13]
- Delivering therapeutics to mucosal tissues such as the nasal and gastrointestinal tracts is highly desirable due to ease of access and dense vasculature. However, the mucus layer effectively captures and removes most the...
- The intracellular plasmid DNA localization of cationic reducible cholesterol-disulfide lipids
[作者:Sheng, RL; Luo, T; Zhu, YD; Li, H; Sun, JJ; Chen, SD; Sun, WY; Cao, AM,期刊:BIOMATERIALS, 页码:3507-3519 , 文章类型: Article,,卷期:2011年32-13]
- Stimuli-responsive biomaterials derived from natural products toward efficient drug/gene delivery have been attracting increasing attention in the past decade. In this work, we first designed and prepared a new series of...
- Intracellular delivery of quantum dots mediated by a histidine- and arginine-rich HR9 cell-penetrating peptide through the direct membrane translocation mechanism
[作者:Liu, BR; Huang, YW; Winiarz, JG; Chiang, HJ; Lee, HJ,期刊:BIOMATERIALS, 页码:3520-3537 , 文章类型: Article,,卷期:2011年32-13]
- Functional peptides that transfer biomaterials, such as semiconductor quantum dots (QDs), into cells in biomaterial research have been developed in recent years. Delivery of QDs conjugated with cell-penetrating peptides ...
- Improved biological half-life and anti-tumor activity of TNF-related apoptosis-inducing ligand (TRAIL) using PEG-exposed nanoparticles
[作者:Lim, SM; Kim, TH; Jiang, HH; Park, CW; Lee, S; Chen, X; Lee, KC,期刊:BIOMATERIALS, 页码:3538-3546 , 文章类型: Article,,卷期:2011年32-13]
- TRAIL has received considerable attention as a potential anti-cancer agent due to its specific ability to target tumors. However, recombinant TRAIL has several limitations, such as, its short biological half-life, its in...
- Keratin films for ocular surface reconstruction
[作者:Reichl, S; Borrelli, M; Geerling, G,期刊:BIOMATERIALS, 页码:3375-3386 , 文章类型: Article,,卷期:2011年32-13]
- Human amniotic membrane (AM) is frequently used as a substrate for ocular surface reconstruction. Its disadvantages (e.g., reduced transparency and biomechanical strength, heterogeneity depending on donor) create the nee...
- Mechanical properties and in vivo behavior of a biodegradable synthetic polymer microfiber-extracellular matrix hydrogel biohybrid scaffold
[作者:Hong, Y; Huber, A; Takanari, K; Amoroso, NJ; Hashizume, R; Badylak, SF; Wagner, WR,期刊:BIOMATERIALS, 页码:3387-3394 , 文章类型: Article,,卷期:2011年32-13]
- A biohybrid composite consisting of extracellular matrix (ECM) gel from porcine dermal tissue and biodegradable elastomeric fibers was generated and evaluated for soft tissue applications. ECM gel possesses attractive bi...
- The effects of combined micron-/submicron-scale surface roughness and nanoscale features on cell proliferation and differentiation
[作者:Gittens, RA; McLachlan, T; Olivares-Navarrete, R; Cai, Y; Berner, S; Tannenbaum, R; Schwartz, Z; Sandhage, KH; Boyan, BD,期刊:BIOMATERIALS, 页码:3395-3403 , 文章类型: Article,,卷期:2011年32-13]
- Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants. Previous studies have shown that surface roughness at the micro- and submicro-scales promotes osseointegration by enhancing os...
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