- Microvesicles and Viral Infection
[作者:Meckes, DG; Raab-Traub, N,期刊:Journal of virology, 页码:12844-12854 , 文章类型: Review,,卷期:2011年85-24]
- ;Cells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in ...
- Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion Promotion
[作者:Bose, S; Welch, BD; Kors, CA; Yuan, P; Jardetzky, TS; Lamb, RA,期刊:Journal of virology, 页码:12855-12866 , 文章类型: Article,,卷期:2011年85-24]
- Paramyxovirus entry into cells requires the fusion protein (F) and a receptor binding protein (hemagglutinin-neuraminidase [HN], H, or G). The multifunctional HN protein of some paramyxoviruses, besides functioning as th...
- Functional Genomics Reveals an Essential and Specific Role for Stat1 in Protection of the Central Nervous System following Herpes Simplex Virus Corneal Infection
[作者:Pasieka, TJ; Cilloniz, C; Carter, VS; Rosato, P; Katze, MG; Leib, DA,期刊:Journal of virology, 页码:12972-12981 , 文章类型: Article,,卷期:2011年85-24]
- Innate immune deficiencies result in a spectrum of severe clinical outcomes following infection. In particular, there is a strong association between loss of the signal transducer and activator of transcription (Stat) pa...
- Infection of Nonhost Species Dendritic Cells In Vitro with an Attenuated Myxoma Virus Induces Gene Expression That Predicts Its Efficacy as a Vaccine Vector
[作者:Top, S; Foulon, E; Pignolet, B; Deplanche, M; Caubet, C; Tasca, C; Bertagnoli, S; Meyer, G; Foucras, G,期刊:Journal of virology, 页码:12982-12994 , 文章类型: Article,,卷期:2011年85-24]
- Recombinant myxoma virus (MYXV) can be produced without a loss of infectivity, and its highly specific host range makes it an ideal vaccine vector candidate, although careful examination of its interaction with the immun...
- Genomic Sequencing and Characterization of Cynomolgus Macaque Cytomegalovirus
[作者:Marsh, AK; Willer, DO; Ambagala, APN; Dzamba, M; Chan, JK; Pilon, R; Fournier, J; Sandstrom, P; Brudno, M; MacDonald, KS,期刊:Journal of virology, 页码:12995-13009 , 文章类型: Article,,卷期:2011年85-24]
- Cytomegalovirus (CMV) infection is the most common opportunistic infection in immunosuppressed individuals, such as transplant recipients or people living with HIV/AIDS, and congenital CMV is the leading viral cause of d...
- A Virus-Like Particle-Based Epstein-Barr Virus Vaccine
[作者:Ruiss, R; Jochum, S; Wanner, G; Reisbach, G; Hammerschmidt, W; Zeidler, R,期刊:Journal of virology, 页码:13105-13113 , 文章类型: Article,,卷期:2011年85-24]
- Epstein-Barr Virus (EBV) is an ubiquitous human herpesvirus which can lead to infectious mononucleosis and different cancers. In immunocompromised individuals, this virus is a major cause for morbidity and mortality. Tra...
- Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors
[作者:Yu, D; Jin, C; Leja, J; Majdalani, N; Nilsson, B; Eriksson, F; Essand, M,期刊:Journal of virology, 页码:13114-13123 , 文章类型: Article,,卷期:2011年85-24]
- Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surfaces of tum...
- Cardiotrophin-1 Promotes a High Survival Rate in Rabbits with Lethal Fulminant Hepatitis of Viral Origin
[作者:Tunon, MJ; San Miguel, B; Crespo, I; Riezu-Boj, JI; Larrea, E; Alvarez, M; Gonzalez, I; Bustos, M; Gonzalez-Gallego, J; Prieto, J,期刊:Journal of virology, 页码:13124-13132 , 文章类型: Article,,卷期:2011年85-24]
- Rabbit hemorrhagic disease virus (RHDV) causes lethal fulminant hepatitis closely resembling acute liver failure (ALF) in humans. In this study, we investigated whether cardiotrophin-1 (CT-1), a cytokine with hepatoprote...
- Spring-Loaded Model Revisited: Paramyxovirus Fusion Requires Engagement of a Receptor Binding Protein beyond Initial Triggering of the Fusion Protein
[作者:Porotto, M; DeVito, I; Palmer, SG; Jurgens, EM; Yee, JL; Yokoyama, CC; Pessi, A; Moscona, A,期刊:Journal of virology, 页码:12867-12880 , 文章类型: Article,,卷期:2011年85-24]
- During paramyxovirus entry into a host cell, receptor engagement by a specialized binding protein triggers conformational changes in the adjacent fusion protein (F), leading to fusion between the viral and cell membranes...
- ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication
[作者:Raychoudhuri, A; Shrivastava, S; Steele, R; Kim, H; Ray, R; Ray, RB,期刊:Journal of virology, 页码:12881-12889 , 文章类型: Article,,卷期:2011年85-24]
- Hepatitis C virus (HCV) often leads to persistent infection. Interferon (IFN) and IFN-stimulated genes (ISGs) are amplified during HCV infection but fail to eliminate virus from the liver in a large number of infected pa...
- Generation and Comprehensive Analysis of an Influenza Virus Polymerase Cellular Interaction Network
[作者:Tafforeau, L; Chantier, T; Pradezynski, F; Pellet, J; Mangeot, PE; Vidalain, PO; Andre, P; Rabourdin-Combe, C; Lotteau, V,期刊:Journal of virology, 页码:13010-13018 , 文章类型: Article,,卷期:2011年85-24]
- The influenza virus transcribes and replicates its genome inside the nucleus of infected cells. Both activities are performed by the viral RNA-dependent RNA polymerase that is composed of the three subunits PA, PB1, and ...
- A Virion-Associated Protein Kinase Induces Apoptosis
[作者:Chitnis, NS; Paul, ER; Lawrence, PK; Henderson, CW; Ganapathy, S; Taylor, PV; Virdi, KS; D'Costa, SM; May, AR; Bilimoria, SL,期刊:Journal of virology, 页码:13144-13152 , 文章类型: Article,,卷期:2011年85-24]
- Apoptosis and inhibition of host gene expression are often associated with virus infections. Many viral polypeptides modulate apoptosis by direct interaction with highly conserved apoptotic pathways. Some viruses induce ...
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