- Vesicular Stomatitis Virus-Simian Retrovirus Type 2 Vaccine Protects Macaques from Detectable Infection and B-Cell Destruction
[作者:Gautam, R; Iyer, A; Hunter, M; Das, A; Williams, T; Dufour, J; Apetrei, C; Kousoulas, KG; Marx, PA,期刊:Journal of virology, 页码:5889-5896 , 文章类型: Article,,卷期:2011年85-12]
- Natural infection with simian retrovirus (SRV) has long been recognized in rhesus macaques (RMs) and may result in an AIDS-like disease. Importantly, SRV infections persist as a problem in recently imported macaques. The...
- Genome-Wide Analysis of the 5 ' and 3 ' Ends of Vaccinia Virus Early mRNAs Delineates Regulatory Sequences of Annotated and Anomalous Transcripts
[作者:Yang, Z; Bruno, DP; Martens, CA; Porcella, SF; Moss, B,期刊:Journal of virology, 页码:5897-5909 , 文章类型: Article,,卷期:2011年85-12]
- Poxviruses are large DNA viruses that encode a multisubunit RNA polymerase, stage-specific transcription factors, and enzymes that cap and polyadenylate mRNAs within the cytoplasm of infected animal cells. Genome-wide mi...
- Receptor-Ligand Requirements for Increased NK Cell Polyfunctional Potential in Slow Progressors Infected with HIV-1 Coexpressing KIR3DL1*h/*y and HLA-B*57
[作者:Kamya, P; Boulet, S; Tsoukas, CM; Routy, JP; Thomas, R; Cote, P; Boulassel, MR; Baril, JG; Kovacs, C; Migueles, SA; Connors, M; Suscovich, TJ; Brander, C; Tremblay, CL; Bernard, N,期刊:Journal of virology, 页码:5949-5960 , 文章类型: Article,,卷期:2011年85-12]
- Carriage of the natural killer (NK) receptor genotype KIR3DL1*h/*y with its HLA-B*57 ligand (*h/*y+B*57) is associated with slow time to AIDS and low viral load (VL). To provide a functional basis for these epidemiologic...
- Complexity and Catalytic Efficiency of Hepatitis C Virus (HCV) NS3 and NS4A Protease Quasispecies Influence Responsiveness to Treatment with Pegylated Interferon plus Ribavirin in HCV/HIV-Coinfected Patients
[作者:Aparicio, E; Franco, S; Parera, M; Andres, C; Tural, C; Clotet, B; Martinez, MA,期刊:Journal of virology, 页码:5961-5969 , 文章类型: Article,,卷期:2011年85-12]
- The role of the hepatitis C virus (HCV) NS3/4A protease in ablating the signaling pathway involved in the production of alpha/beta interferon (IFN-alpha/beta) suggests a relationship between NS3/4A proteolytic activity a...
- Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules
[作者:Fadda, L; O'Connor, GM; Kumar, S; Piechocka-Trocha, A; Gardiner, CM; Carrington, M; McVicar, DW; Altfeld, M,期刊:Journal of virology, 页码:5970-5974 , 文章类型: Article,,卷期:2011年85-12]
- Epidemiological studies have shown the protective effect of KIR3DL1/HLA-Bw4 genotypes in human immunodeficiency virus type 1 (HIV-1) infection; however, the functional correlates for the protective effect remain unknown....
- Measles Virus Glycoprotein-Pseudotyped Lentiviral Vector-Mediated Gene Transfer into Quiescent Lymphocytes Requires Binding to both SLAM and CD46 Entry Receptors
[作者:Frecha, C; Levy, C; Costa, C; Negre, D; Amirache, F; Buckland, R; Russell, SJ; Cosset, FL; Verhoeyen, E,期刊:Journal of virology, 页码:5975-5985 , 文章类型: Article,,卷期:2011年85-12]
- Gene transfer into quiescent T and B cells is of importance for gene therapy and immunotherapy approaches to correct hematopoietic disorders. Previously, we generated lentiviral vectors (LVs) pseudotyped with the Edmonst...
- Cytomegalovirus e127 Protein Interacts with the Inhibitory CD200 Receptor
[作者:Foster-Cuevas, M; Westerholt, T; Ahmed, M; Brown, MH; Barclay, AN; Voigt, S,期刊:Journal of virology, 页码:6055-6059 , 文章类型: Article,,卷期:2011年85-12]
- CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) i...
- Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4(+) T Cell Model without Inducing Global T Cell Activation
[作者:Xing, SF; Bullen, CK; Shroff, NS; Shan, L; Yang, HC; Manucci, JL; Bhat, S; Zhang, H; Margolick, JB; Quinn, TC; Margolis, DM; Siliciano, JD; Siliciano, RF,期刊:Journal of virology, 页码:6060-6064 , 文章类型: Article,,卷期:2011年85-12]
- Highly active antiretroviral therapy (HAART) can reduce plasma HIV-1 levels to below the detection limit. However, due to the latent reservoir in resting CD4(+) cells, HAART is not curative. Elimination of this reservoir...
- Temporal Profiling of the Coding and Noncoding Murine Cytomegalovirus Transcriptomes
[作者:Lacaze, P; Forster, T; Ross, A; Kerr, LE; Salvo-Chirnside, E; Lisnic, VJ; Lopez-Campos, GH; Garcia-Ramirez, JJ; Messerle, M; Trgovcich, J; Angulo, A; Ghazal, P,期刊:Journal of virology, 页码:6065-6076 , 文章类型: Article,,卷期:2011年85-12]
- The global transcriptional program of murine cytomegalovirus (MCMV), involving coding, noncoding, and antisense transcription, remains unknown. Here we report an oligonucleotide custom microarray platform capable of meas...
- Electron Tomography Reveals Polyhedrin Binding and Existence of both Empty and Full Cytoplasmic Polyhedrosis Virus Particles inside Infectious Polyhedra
[作者:Chen, J; Sun, JC; Atanasov, I; Ryazantsev, S; Zhou, ZH,期刊:Journal of virology, 页码:6077-6081 , 文章类型: Article,,卷期:2011年85-12]
- Previous studies have described the structure of purified cytoplasmic polyhedrosis virus (CPV) and that of polyhedrin protein. However, how polyhedrin molecules embed CPV particles inside infectious polyhedra is not know...
- Discrimination of Mumps Virus Small Hydrophobic Gene Deletion Effects from Gene Translation Effects on Virus Virulence
[作者:Malik, T; Shegogue, CW; Werner, K; Ngo, L; Sauder, C; Zhang, C; Duprex, WP; Rubin, S,期刊:Journal of virology, 页码:6082-6085 , 文章类型: Article,,卷期:2011年85-12]
- Deletion of the small hydrophobic (SH) protein of certain paramyxoviruses has been found to result in attenuation, suggesting that the SH protein is a virulence factor. To investigate the role of the mumps virus (MuV) SH...
- Partial Functional Complementation between Human and Mouse Cytomegalovirus Chemokine Receptor Homologues
[作者:Farrell, HE; Abraham, AM; Cardin, RD; Sparre-Ulrich, AH; Rosenkilde, MM; Spiess, K; Jensen, TH; Kledal, TN; Davis-Poynter, N,期刊:Journal of virology, 页码:6091-6095 , 文章类型: Article,,卷期:2011年85-12]
- The human cytomegalovirus (CMV) proteins US28 and UL33 are homologous to chemokine receptors (CKRs). Knockout of the mouse CMV M33 protein (UL33 homologue) results in substantial attenuation of salivary gland infection/r...
- Coxsackievirus Preferentially Replicates and Induces Cytopathic Effects in Undifferentiated Neural Progenitor Cells
[作者:Tsueng, G; Tabor-Godwin, JM; Gopal, A; Ruller, CM; Deline, S; An, N; Frausto, RF; Milner, R; Crocker, SJ; Whitton, JL; Feuer, R,期刊:Journal of virology, 页码:5718-5732 , 文章类型: Article,,卷期:2011年85-12]
- Enteroviruses, including coxsackieviruses, exhibit significant tropism for the central nervous system, and these viruses are commonly associated with viral meningitis and encephalitis. Previously, we described the abilit...
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