- RAB11A Is Essential for Transport of the Influenza Virus Genome to the Plasma Membrane
[作者:Eisfeld, AJ; Kawakami, E; Watanabe, T; Neumann, G; Kawaoka, Y,期刊:Journal of virology, 页码:6117-6126 , 文章类型: Article,,卷期:2011年85-13]
- Influenza A virus assembly is a complex process that requires the intersection of pathways involved in transporting viral glycoproteins, the matrix protein, and viral genomes, incorporated in the viral ribonucleoprotein ...
- Spatiotemporally Different DNA Repair Systems Participate in Epstein-Barr Virus Genome Maturation
[作者:Sugimoto, A; Kanda, T; Yamashita, Y; Murata, T; Saito, S; Kawashima, D; Isomura, H; Nishiyama, Y; Tsurumi, T,期刊:Journal of virology, 页码:6127-6135 , 文章类型: Article,,卷期:2011年85-13]
- Productive replication of Epstein-Barr virus occurs in discrete sites in nuclei, called replication compartments, where viral DNA replication proteins and host homologous recombinational repair (HRR) and mismatch repair ...
- Molecular Mechanisms of Viral and Host Cell Substrate Recognition by Hepatitis C Virus NS3/4A Protease
[作者:Romano, KP; Laine, JM; Deveau, LM; Cao, H; Massi, F; Schiffer, CA,期刊:Journal of virology, 页码:6106-6116 , 文章类型: Article,,卷期:2011年85-13]
- Hepatitis C NS3/4A protease is a prime therapeutic target that is responsible for cleaving the viral polyprotein at junctions 3-4A, 4A4B, 4B5A, and 5A5B and two host cell adaptor proteins of the innate immune response, T...
- Detection of Chronic Wasting Disease Prions in Salivary, Urinary, and Intestinal Tissues of Deer: Potential Mechanisms of Prion Shedding and Transmission
[作者:Haley, NJ; Mathiason, CK; Carver, S; Zabel, M; Telling, GC; Hoover, EA,期刊:Journal of virology, 页码:6309-6318 , 文章类型: Article,,卷期:2011年85-13]
- Efficient horizontal transmission is a signature trait of chronic wasting disease (CWD) in cervids. Infectious prions shed into excreta appear to play a key role in this facile transmission, as has been demonstrated by b...
- Subversion of Cellular Autophagy Machinery by Hepatitis B Virus for Viral Envelopment
[作者:Li, JH; Liu, YH; Wang, ZK; Liu, KC; Wang, YH; Liu, JX; Ding, HP; Yuan, ZH,期刊:Journal of virology, 页码:6319-6333 , 文章类型: Article,,卷期:2011年85-13]
- Autophagy is a conserved eukaryotic mechanism that mediates the removal of long-lived cytoplasmic macromolecules and damaged organelles via a lysosomal degradative pathway. Recently, a multitude of studies have reported ...
- Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action
[作者:Targett-Adams, P; Graham, EJS; Middleton, J; Palmer, A; Shaw, SM; Lavender, H; Brain, P; Tran, TD; Jones, LH; Wakenhut, F; Stammen, B; Pryde, D; Pickford, C; Westby, M,期刊:Journal of virology, 页码:6353-6368 , 文章类型: Article,,卷期:2011年85-13]
- The current standard of care for hepatitis C virus (HCV)-infected patients consists of lengthy treatment with interferon and ribavirin. To increase the effectiveness of HCV therapy, future regimens will incorporate multi...
- Temporal Variations in the Hepatitis C Virus Intrahost Population during Chronic Infection
[作者:Ramachandran, S; Campo, DS; Dimitrova, ZE; Xia, GL; Purdy, MA; Khudyakov, YE,期刊:Journal of virology, 页码:6369-6380 , 文章类型: Article,,卷期:2011年85-13]
- The intrahost evolution of hepatitis C virus (HCV) holds keys to understanding mechanisms responsible for the establishment of chronic infections and to development of a vaccine and therapeutics. In this study, intrahost...
- Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication
[作者:Cencic, R; Desforges, M; Hall, DR; Kozakov, D; Du, YH; Min, J; Dingledine, R; Fu, HA; Vajda, S; Talbot, PJ; Pelletier, J,期刊:Journal of virology, 页码:6381-6389 , 文章类型: Article,,卷期:2011年85-13]
- Coronaviruses are a family of enveloped single-stranded positive-sense RNA viruses causing respiratory, enteric, and neurologic diseases in mammals and fowl. Human coronaviruses are recognized to cause up to a third of c...
- Multimerization of Adenovirus Serotype 3 Fiber Knob Domains Is Required for Efficient Binding of Virus to Desmoglein 2 and Subsequent Opening of Epithelial Junctions
[作者:Wang, HJ; Li, ZY; Yumul, R; Lara, S; Hemminki, A; Fender, P; Lieber, A,期刊:Journal of virology, 页码:6390-6402 , 文章类型: Article,,卷期:2011年85-13]
- Recently, we identified desmoglein 2 (DSG2) as the main receptor for a group of species B adenoviruses (Ads), including Ad3, a serotype that is widely distributed in the human population (H. Wang et al., Nat. Med. 17: 96...
- Evolution of Drug-Resistant Viral Populations during Interruption of Antiretroviral Therapy
[作者:Wang, DN; Hicks, CB; Goswami, ND; Tafoya, E; Ribeiro, RM; Cai, FP; Perelson, AS; Gao, F,期刊:Journal of virology, 页码:6403-6415 , 文章类型: Article,,卷期:2011年85-13]
- Analysis of a large number of HIV-1 genomes at multiple time points after antiretroviral treatment (ART) interruption allows determination of the evolution of drug-resistant viruses and viral fitness in vivo in the absen...
- Entry of Tiger Frog Virus (an Iridovirus) into HepG2 Cells via a pH-Dependent, Atypical, Caveola-Mediated Endocytosis Pathway
[作者:Guo, CJ; Liu, D; Wu, YY; Yang, XB; Yang, LS; Mi, S; Huang, YX; Luo, YW; Jia, KT; Liu, ZY; Chen, WJ; Weng, SP; Yu, XQ; He, JG,期刊:Journal of virology, 页码:6416-6426 , 文章类型: Article,,卷期:2011年85-13]
- Tiger frog virus (TFV), in the genus Ranavirus of the family Iridoviridae, causes high mortality of cultured tiger frog tadpoles in China. To explore the cellular entry mechanism of TFV, HepG2 cells were treated with dru...
- A5-Positive Primary Sensory Neurons Are Nonpermissive for Productive Infection with Herpes Simplex Virus 1 In Vitro
[作者:Bertke, AS; Swanson, SM; Chen, J; Imai, Y; Kinchington, PR; Margolis, TP,期刊:Journal of virology, 页码:6669-6677 , 文章类型: Article,,卷期:2011年85-13]
- Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) establish latency and express the latency-associated transcript (LAT) preferentially in different murine sensory neuron populations, with most HSV-1 LAT expression in A5(+...
- Varicella-Zoster Virus Infection of Differentiated Human Neural Stem Cells
[作者:Pugazhenthi, S; Nair, S; Velmurugan, K; Liang, QL; Mahalingam, R; Cohrs, RJ; Nagel, MA; Gilden, D,期刊:Journal of virology, 页码:6678-6686 , 文章类型: Article,,卷期:2011年85-13]
- Primary varicella-zoster virus (VZV) infection in humans produces varicella (chickenpox), after which the virus becomes latent in ganglionic neurons. Analysis of the physical state of viral nucleic acid and virus gene ex...
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