- Effect of an Asparagine-to-Serine Mutation at Position 294 in Neuraminidase on the Pathogenicity of Highly Pathogenic H5N1 Influenza A Virus
[作者:Kiso, M; Ozawa, M; Mai, TQL; Imai, H; Takahashi, K; Kakugawa, S; Noda, T; Horimoto, T; Kawaoka, Y,期刊:Journal of virology, 页码:4667-4672 , 文章类型: Article,,卷期:2011年85-10]
- Like the histidine-to-tyrosine substitution at position 274 in neuraminidase (NA H274Y), an asparagine-to-serine mutation at position 294 in this protein (NA N294S) confers oseltamivir resistance to highly pathogenic H5N...
- Systemic Dissemination of H5N1 Influenza A Viruses in Ferrets and Hamsters after Direct Intragastric Inoculation
[作者:Shinya, K; Makino, A; Tanaka, H; Hatta, M; Watanabe, T; Le, MQ; Imai, H; Kawaoka, Y,期刊:Journal of virology, 页码:4673-4678 , 文章类型: Article,,卷期:2011年85-10]
- Although oral exposure to H5N1 highly pathogenic avian influenza viruses is a risk factor for infection in humans, it is unclear how oral exposure to these virus results in lethal respiratory infections. To address this ...
- Role of Nrf2 in Host Defense against Influenza Virus in Cigarette Smoke-Exposed Mice
[作者:Yageta, Y; Ishii, Y; Morishima, Y; Masuko, H; Ano, S; Yamadori, T; Itoh, K; Takeuchi, K; Yamamoto, M; Hizawa, N,期刊:Journal of virology, 页码:4679-4690 , 文章类型: Article,,卷期:2011年85-10]
- Influenza virus is a common respiratory tract viral infection. Although influenza can be fatal in patients with chronic pulmonary diseases such as chronic obstructive pulmonary disease, its pathogenesis is not fully unde...
- Role of the Herpes Simplex Virus 1 Us3 Kinase Phosphorylation Site and Endocytosis Motifs in the Intracellular Transport and Neurovirulence of Envelope Glycoprotein B
[作者:Imai, T; Arii, J; Minowa, A; Kakimoto, A; Koyanagi, N; Kato, A; Kawaguchi, Y,期刊:Journal of virology, 页码:5003-5015 , 文章类型: Article,,卷期:2011年85-10]
- Herpes simplex virus 1 (HSV-1) Us3 protein kinase phosphorylates threonine at position 887 (Thr-887) in the cytoplasmic tail of envelope glycoprotein B (gB) in infected cells. This phosphorylation downregulates cell surf...
- Deletion of Major Nonessential Genomic Regions in the Vaccinia Virus Lister Strain Enhances Attenuation without Altering Vaccine Efficacy in Mice
[作者:Dimier, J; Ferrier-Rembert, A; Pradeau-Aubreton, K; Hebben, M; Spehner, D; Favier, AL; Gratier, D; Garin, D; Crance, JM; Drillien, R,期刊:Journal of virology, 页码:5016-5026 , 文章类型: Article,,卷期:2011年85-10]
- The vaccinia virus (VACV) Lister strain was one of the vaccine strains that enabled smallpox eradication. Although the strain is most often harmless, there have been numerous incidents of mild to life-threatening acciden...
- Structure of Bombyx mori Densovirus 1, a Silkworm Pathogen
[作者:Kaufmann, B; El-Far, M; Plevka, P; Bowman, VD; Li, Y; Tijssen, P; Rossmann, MG,期刊:Journal of virology, 页码:4691-4697 , 文章类型: Article,,卷期:2011年85-10]
- Bombyx mori densovirus 1 (BmDNV-1), a major pathogen of silkworms, causes significant losses to the silk industry. The structure of the recombinant BmDNV-1 virus-like particle has been determined at 3.1-angstrom resoluti...
- FUSE Binding Protein 1 Interacts with Untranslated Regions of Japanese Encephalitis Virus RNA and Negatively Regulates Viral Replication
[作者:Chien, HL; Liao, CL; Lin, YL,期刊:Journal of virology, 页码:4698-4706 , 文章类型: Article,,卷期:2011年85-10]
- The untranslated regions (UTRs) located at the 5' and 3' ends of the Japanese encephalitis virus (JEV) genome, a positive-sense RNA, are involved in viral translation, the initiation of RNA synthesis, and the packaging o...
- Regulation of Antinucleoprotein IgG by Systemic Vaccination and Its Effect on Influenza Virus Clearance
[作者:LaMere, MW; Moquin, A; Lee, FEH; Misra, RS; Blair, PJ; Haynes, L; Randall, TD; Lund, FE; Kaminski, DA,期刊:Journal of virology, 页码:5027-5035 , 文章类型: Article,,卷期:2011年85-10]
- Seasonal influenza epidemics recur due to antigenic drift of envelope glycoprotein antigens and immune evasion of circulating viruses. Additionally, antigenic shift can lead to influenza pandemics. Thus, a universal vacc...
- Development of a Glycoprotein D-Expressing Dominant-Negative and Replication-Defective Herpes Simplex Virus 2 (HSV-2) Recombinant Viral Vaccine against HSV-2 Infection in Mice
[作者:Akhrameyeva, NV; Zhang, PW; Sugiyama, N; Behar, SM; Yao, F,期刊:Journal of virology, 页码:5036-5047 , 文章类型: Article,,卷期:2011年85-10]
- Using the T-REx (Invitrogen, California) gene switch technology and a dominant-negative mutant polypeptide of herpes simplex virus 1 (HSV-1)-origin binding protein UL9, we previously constructed a glycoprotein D-expressi...
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