- Interaction of Sp1 zinc finger with transport factor in the nuclear localization of transcription factor Sp1
[作者:Ito, T; Kitamura, H; Uwatoko, C; Azumano, M; Itoh, K; Kuwahara, J,期刊:Biochemical and Biophysical Research Communications, 页码:161-166 , 文章类型: Article,,卷期:2010年403-2]
- Transcription factor Sp1 is localized in the nucleus and regulates the expression of many cellular genes, but the nuclear transport mechanism of Sp1 is not well understood. In this study, we revealed that GST-fused Sp1 p...
- Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking
[作者:Kim, E; Lee, Y; Lee, HJ; Kim, JS; Song, BS; Huh, JW; Lee, SR; Kim, SU; Kim, SH; Hong, Y; Shim, I; Chang, KT,期刊:Biochemical and Biophysical Research Communications, 页码:167-171 , 文章类型: Article,,卷期:2010年403-2]
- The retromer complex, which mediates retrograde transport from endosomes to the trans-Golgi network, is a heteropentameric complex that contains a multifunctional cargo recognition heterotrimer consisted of the vacuolar ...
- A site-specific genomic integration strategy for sustained expression of glucagon-like peptide-1 in mouse muscle for controlling energy homeostasis
[作者:Liu, R; Li, YM; Hu, RM; Jin, TR; Deng, SS; Liang, W; Zhang, NN; Chen, JZ; Prud'homme, GJ; Jia, WW; Ma, DA; Wang, QH,期刊:Biochemical and Biophysical Research Communications, 页码:172-177 , 文章类型: Article,,卷期:2010年403-2]
- The incretin hormone glucagon-like peptide-1 (GLP-1) exerts important functions in controlling glucose and energy homeostasis. Endogenous GLP-1 has a very short half-life due to DPP-IV-mediated degradation and renal clea...
- Transcriptional regulation of the hypocretin/orexin gene by NR6A1
[作者:Tanaka, S; Kodama, T; Nonaka, T; Toyoda, H; Arai, M; Fukazawa, M; Honda, Y; Honda, M; Mignot, E,期刊:Biochemical and Biophysical Research Communications, 页码:178-183 , 文章类型: Article,,卷期:2010年403-2]
- The hypocretin (also known as orexin) neuropeptide system coordinates the regulation of various physiological processes. A reduction in Nr6a1 expression was observed in hypocretin neuron-ablated transgenic mice. To show ...
- Kaposi's sarcoma-associated herpesvirus-encoded LANA positively affects on ubiquitylation of p53
[作者:Suzuki, T; Isobe, T; Kitagawa, M; Ueda, K,期刊:Biochemical and Biophysical Research Communications, 页码:194-197 , 文章类型: Article,,卷期:2010年403-2]
- We established a series of stable transfectants expressing wild-type and three mutant LANA; amino terminus, carboxyl terminus and amino terminus plus DNA binding domain, as a new strategy to assess systematically the int...
- Further insight into the roles of the glycans attached to human blood protein C inhibitor
[作者:Sun, W; Parry, S; Ubhayasekera, W; Engstrom, A; Dell, A; Schedin-Weiss, S,期刊:Biochemical and Biophysical Research Communications, 页码:198-202 , 文章类型: Article,,卷期:2010年403-2]
- Protein C inhibitor (PCI) is a 57-kDa glycoprotein that exists in many tissues and secretions in human. As a member of the serpin superfamily of proteins it displays unusually broad protease specificity. PCI is implicate...
- Thermal-induced conformational changes in the product release area drive the enzymatic activity of xylanases 10B: Crystal structure, conformational stability and functional characterization of the xylanase 10B from Thermotoga petrophila RKU-1
[作者:Santos, CR; Meza, AN; Hoffmam, ZB; Silva, JC; Alvarez, TM; Ruller, R; Giesel, GM; Verli, H; Squina, FM; Prade, RA; Murakami, MT,期刊:Biochemical and Biophysical Research Communications, 页码:214-219 , 文章类型: Article,,卷期:2010年403-2]
- Endo-xylanases play a key role in the depolymerization of xylan and recently, they have attracted much attention owing to their potential applications on biofuels and paper industries. In this work, we have investigated ...
- Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress
[作者:Hayakawa, H; Fujikane, A; Ito, R; Matsumoto, M; Nakayama, KI; Sekiguchi, M,期刊:Biochemical and Biophysical Research Communications, 页码:220-224 , 文章类型: Article,,卷期:2010年403-2]
- Exposure of cells to oxygen radicals damage various biologically important molecules. Among the oxidized bases produced in nucleic acids, 8-oxo-7,8-dihydroguanine (8-oxoguanine) is particularly important since it causes ...
- Biological characterization and structure based prediction of insulin-like growth factor binding protein-5
[作者:Sung, M; Jeong, MS; Jang, SB,期刊:Biochemical and Biophysical Research Communications, 页码:230-236 , 文章类型: Article,,卷期:2010年403-2]
- The insulin-like growth factor binding protein (IGFBP) family has been shown to play a role in various functions such as cell growth, cell death, cell motility, and tissue remodeling. Among the 7 IGFBP family members, IG...
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