- Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma
[作者:Adams, H; Fritzsche, FR; Dirnhofer, S; Kristiansen, G; Tzankov, A,期刊:Expert Opinion on Therapeutic Targets, 页码:577-584 , 文章类型: Article,,卷期:2010年14-6]
- Objective: HDAC inhibitors (HDI) are anti-neoplastic drugs with preliminary successful clinical applications in Hodgkin's lymphoma (HL). Systematic investigations of HDAC expression in HL, based on histology and immunohi...
- PAR-4 as a possible new target for pancreatic cancer therapy
[作者:Azmi, AS; Philip, PA; Zafar, SF; Sarkar, FH; Mohammad, RM,期刊:Expert Opinion on Therapeutic Targets, 页码:611-620 , 文章类型: Review,,卷期:2010年14-6]
- Importance of the field: Pancreatic cancer ( PC) is a deadly disease that is intractable to currently available treatment regimens. Although well described in different tumors types, the importance of apoptosis inducer p...
- The cancer stem cell paradigm: a new understanding of tumor development and treatment
[作者:Ebben, JD; Treisman, DM; Zorniak, M; Kutty, RG; Clark, PA; Kuo, JS,期刊:Expert Opinion on Therapeutic Targets, 页码:621-632 , 文章类型: Review,,卷期:2010年14-6]
- Importance of the field: Cancer is the second leading cause of death in the United States, and therefore remains a central focus of modern medical research. Accumulating evidence supports a 'cancer stem cell' (CSC) model...
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