- Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells
[作者：Renstrom, J; Istvanffy, R; Gauthier, K; Shimono, A; Mages, J; Jardon-Alvarez, A; Kroger, M; Schiemann, M; Busch, DH; Esposito, I; Lang, R; Peschel, C; Oostendorp, RAJ,期刊：Cell Stem Cell, 页码：157-167 , 文章类型： Article，,卷期：2009年5-2]
- Secreted frizzled-related protein 1 (Sfrp1) is highly expressed by stromal cells maintaining hematopoietic stem cells (HSCs). Sfrp1 loss in stromal cells increases production of hematopoietic progenitors, and in knockout...
- DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency
[作者：Hoey, T; Yen, WC; Axelrod, F; Basi, J; Donigian, L; Dylla, S; Fitch-Bruhns, M; Lazetic, S; Park, IK; Sato, A; Satyal, S; Wang, XH; Clarke, MF; Lewicki, J; Gurney, A,期刊：Cell Stem Cell, 页码：168-177 , 文章类型： Article，,卷期：2009年5-2]
- Previous studies have shown that blocking DLL4 signaling reduced tumor growth by disrupting productive angiogenesis. We developed selective anti-human and anti-mouse DLL4 antibodies to dissect the mechanisms involved by ...
- The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair
[作者：Corsini, NS; Sancho-Martinez, I; Laudenklos, S; Glagow, D; Kumar, S; Letellier, E; Koch, P; Teodorczyk, M; Kleber, S; Klussmann, S; Wiestler, B; Brustle, O; Mueller, W; Gieffers, C; Hill, O; Thiemann, M; Seedorf, M; Gretz, N; Sprengel, R; Celikel, T; Martin-Villalba, A,期刊：Cell Stem Cell, 页码：178-190 , 文章类型： Article，,卷期：2009年5-2]
- Adult neurogenesis persists in the subventricular zone and the dentate gyrus and can be induced upon central nervous system injury. However, the final contribution of newborn neurons to neuronal networks is limited. Here...
- Phosphoproteomic Analysis of Human Embryonic Stem Cells
[作者：Brill, LM; Xiong, W; Lee, KB; Ficarro, SB; Crain, A; Xu, Y; Terskikh, A; Snyder, EY; Ding, S,期刊：Cell Stem Cell, 页码：204-213 , 文章类型： Article，,卷期：2009年5-2]
- Protein phosphorylation, while critical to cellular behavior, has been undercharacterized in pluripotent cells. Therefore, we performed phosphoproteomic analyses of human embryonic stem cells (hESCs) and their differenti...
- Phosphorylation Dynamics during Early Differentiation of Human Embryonic Stem Cells
[作者：Van Hoof, D; Munoz, J; Braam, SR; Pinkse, MWH; Linding, R; Heck, AJR; Mummery, CL; Krijgsveld, J,期刊：Cell Stem Cell, 页码：214-226 , 文章类型： Article，,卷期：2009年5-2]
- Pluripotent stem cells, self-renew indefinitely and possess characteristic protein-protein networks that remodel during differentiation. How this occurs is poorly understood. Using quantitative mass spectrometry, we anal...
- Molecular Targeting of Cancer Stem Cells
[作者：Gupta, R; Vyas, P; Enver, T,期刊：Cell Stem Cell, 页码：125-126 , 文章类型： Editorial Material，,卷期：2009年5-2]
- Cancer stem cells may be important targets for new anticancer drugs. In two recent articles in Cell Stem Cell, Jin et al. (2009) and Hoey et al. (2009) provide proof of principle for this idea in experimental models of s...
- CD95/Fas in the Brain-Not Just a Killer
[作者：Beier, CP; Schulz, JB,期刊：Cell Stem Cell, 页码：128-130 , 文章类型： Editorial Material，,卷期：2009年5-2]
- Although CD95 (Fas/Apo-1) has long been known to be broadly expressed in the brain, its function has remained enigmatic. In this issue of Cell Stem Cell, Corsini et al. (2009) now show that CD95 serves as a potent activa...
- Smooth(ing) Muscle Differentiation by MicroRNAs
[作者：Neppl, RL; Wang, DZ,期刊：Cell Stem Cell, 页码：130-132 , 文章类型： Editorial Material，,卷期：2009年5-2]
- In a recent report in Nature, Cordes et al. (2009) demonstrate that miR-143 and miR-145 modulate smooth muscle cell (SMC) plasticity in part by regulating key transcription factors involved in SMC fate determination.
- Adult Muscle Stem Cells Avoid Death and Paxes
[作者：Brack, A,期刊：Cell Stem Cell, 页码：132-134 , 文章类型： Editorial Material，,卷期：2009年5-2]
- In a recent Nature publication, Lepper et al. (2009) use cell-specific lineage tracing and temporally controllable gene deletion approaches to study muscle stem cell function and reveal age-dependent requirements for Pax...
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