- Infrared microspectroscopy analysis of Ibuprofen release from drug eluting beads in uterine tissue
[作者:Namur, J; Wassef, M; Pelage, JP; Lewis, A; Manfait, M; Laurent, A,期刊:Journal of controlled release, 页码:198-202 , 文章类型: Article,,卷期:2009年135-3]
- Ibuprofen loaded embolization beads (IBU-BB) have been developed to reduce inflammation and pain following uterine artery embolization for the treatment of uterine fibroids. The present work has investigated the elution ...
- Bioactive cell-hydrogel microcapsules for cell-based drug delivery
[作者:Orive, G; De Castro, M; Kong, HJ; Hernandez, R; Ponce, S; Mooney, DJ; Pedraz, JL,期刊:Journal of controlled release, 页码:203-210 , 文章类型: Article,,卷期:2009年135-3]
- Improvement of long-term drug release and design of mechanically more stable encapsulation devices are still major challenges in the field of cell encapsulation. This may be in part due to the weak in vivo stability of c...
- SMA-copolymer conjugate of AHPP: A polymeric inhibitor of xanthine oxidase with potential antihypertensive effect
[作者:Fang, J; Iyer, AK; Seki, T; Nakamura, H; Greish, K; Maeda, H,期刊:Journal of controlled release, 页码:211-217 , 文章类型: Article,,卷期:2009年135-3]
- In vascular system, superoxide anion (O-2(-)) generated by xanthine oxidase (XO) is known to regulate vascular tonus by reacting with, and thus consuming nitric oxide (NO), which determines vasorelaxation. We previously ...
- Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination
[作者:Isaji, K; Kawase, A; Matono, M; Guan, X; Nishikawa, M; Takakura, Y,期刊:Journal of controlled release, 页码:227-233 , 文章类型: Article,,卷期:2009年135-3]
- To elicit a cytotoxic T lymphocytes (CTL) response efficiently after DNA vaccination, we constructed several plasmid DNA (pDNA) vectors encoding the major histocompatibility complex (MHC) class I-restricted epitope pepti...
- Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
[作者:Elfinger, M; Geiger, J; Hasenpusch, G; Uzgun, S; Sieverling, N; Aneja, MK; Maucksch, C; Rudolph, C,期刊:Journal of controlled release, 页码:234-241 , 文章类型: Article,,卷期:2009年135-3]
- Coupling of targeting ligands to polyethylenimine (PEI) has been previously used to improve transfection efficiency of PEI gene vectors. Here, we show that the beta(2)-adrenoceptor (beta(2)-AR) agonist, clenbuterol (Clen...
- Transcutaneous immunization by lipoplex-patch based DNA vaccines is effective vaccination against Japanese encephalitis virus infection
[作者:Cheng, JY; Huang, HN; Tseng, WC; Li, TL; Chan, YL; Cheng, KC; Wu, CJ,期刊:Journal of controlled release, 页码:242-249 , 文章类型: Article,,卷期:2009年135-3]
- Skin, the biggest organ of human body, contains antigen presenting cells such as Langerhans cells (LCs) that modulate various immune responses. The skin therefore is an ideal venue to effect the transcutaneous immunizati...
- Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles
[作者:Nam, HY; Kwon, SM; Chung, H; Lee, SY; Kwon, SH; Jeon, H; Kim, Y; Park, JH; Kim, J; Her, S; Oh, YK; Kwon, IC; Kim, K; Jeong, SY,期刊:Journal of controlled release, 页码:259-267 , 文章类型: Article,,卷期:2009年135-3]
- Polymeric nanoparticle-based carriers are promising agents for the targeted delivery of therapeutics to the intracellular site of action. To optimize the efficacy in delivery, often the tuning of physicochemical properti...
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