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  • Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function
    [作者:Pescovitz, MD; Greenbaum, CJ; Krause-Steinrauf, H; Becker, DJ; Gitelman, SE; Goland, R; Gottlieb, PA; Marks, JB; McGee, PF; Moran, AM; Raskin, P; Rodriguez, H; Schatz, DA; Wherrett, D; Wilson, DM; Lachin, JM; Skyler, JS,期刊:New England Journal of Medicine, 页码:2143-2152 , 文章类型: Article,,卷期:2009年361-22]
  • BACKGROUNDThe immunopathogenesis of type 1 diabetes mellitus is associated with T-lymphocyte autoimmunity. However, there is growing evidence that B lymphocytes play a role in many T-lymphocyte-mediated diseases. It is p...