- Human melanoma cells express FGFR/Src/Rho signaling that entails an adhesion-independent caveolin-1 membrane association
[作者：Fecchi, K; Travaglione, S; Spadaro, F; Quattrini, A; Parolini, I; Piccaro, G; Raggi, C; Fabbri, A; Felicetti, F; Care, A; Fiorentini, C; Sargiacomo, M,期刊：International Journal of Cancer, 页码：1273-1283 , 文章类型： Article，,卷期：2012年130-6]
- Caveolae have been indicated as a center of cytoskeleton regulation for Src kinase/Rho GTPase signaling. In addition, Src recruitment on intact cortical actin cytoskeleton appears to be required for bFGF/FGFR signal acti...
- Non-invasive in vivo imaging of vessel calibre in orthotopic prostate tumour xenografts
[作者：Walker-Samuel, S; Boult, JKR; McPhail, LD; Box, G; Eccles, SA; Robinson, SP,期刊：International Journal of Cancer, 页码：1284-1293 , 文章类型： Article，,卷期：2012年130-6]
- Susceptibility contrast magnetic resonance imaging (MRI), utilising ultrasmall superparamagnetic iron oxide (USPIO) particles, was evaluated for the quantitation of vessel size index (Rv, mu m), a weighted average measur...
- Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis
[作者：Okuyama, S; Marusawa, H; Matsumoto, T; Ueda, Y; Matsumoto, Y; Endo, Y; Takai, A; Chiba, T,期刊：International Journal of Cancer, 页码：1294-1301 , 文章类型： Article，,卷期：2012年130-6]
- Apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) was originally identified as a member of the cytidine deaminase family with putative nucleotide editing activity. To clarify the physiologic and path...
- Expression of T-cell lymphoma invasion and metastasis 2 (TIAM2) promotes proliferation and invasion of liver cancer
[作者：Chen, JS; Su, IJ; Leu, YW; Young, KC; Sun, HS,期刊：International Journal of Cancer, 页码：1302-1313 , 文章类型： Article，,卷期：2012年130-6]
- The T-cell lymphoma invasion and metastasis 2 (TIAM2) gene is the homolog of human TIAM1, a Rac-specific guanine nucleotide exchange factor that plays important roles in neuron development and human malignancies. Althoug...
- Association of death receptor 4 variant (683A > C) with ovarian cancer risk in BRCA1 mutation carriers
[作者：Dick, MG; Versmold, B; Engel, C; Meindl, A; Arnold, N; Varon-Mateeva, R; Sutter, C; Niederacher, D; Deissler, H; Preisler-Adams, S; Kast, K; Schafer, D; Gadzicki, D; Heinritz, W; Wappenschmidt, B; Schmutzler, RK,期刊：International Journal of Cancer, 页码：1314-1318 , 文章类型： Article，,卷期：2012年130-6]
- Dysregulation of apoptosis plays an important role in carcinogenesis. Therefore, apoptosis-associated genes like the death receptor 4 (DR4, TRAIL-R1) are interesting candidates for modifying the penetrance of breast and ...
- Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma
[作者：Ammerpohl, O; Pratschke, J; Schafmayer, C; Haake, A; Faber, W; von Kampen, O; Brosch, M; Sipos, B; von Schonfels, W; Balschun, K; Rocken, C; Arlt, A; Schniewind, B; Grauholm, J; Kalthoff, H; Neuhaus, P; Stickel, F; Schreiber, S; Becker, T; Siebert, R; Hampe, J,期刊：International Journal of Cancer, 页码：1319-1328 , 文章类型： Article，,卷期：2012年130-6]
- Abberrant DNA methylation is one of the hallmarks of cancerogenesis. Our study aims to delineate differential DNA methylation in cirrhosis and hepatic cancerogenesis. Patterns of methylation of 27,578 individual CpG loci...
- Aberrations of a cell adhesion molecule CADM4 in renal clear cell carcinoma
[作者：Nagata, M; Sakurai-Yageta, M; Yamada, D; Goto, A; Ito, A; Fukuhara, H; Kume, H; Morikawa, T; Fukayama, M; Homma, Y; Murakami, Y,期刊：International Journal of Cancer, 页码：1329-1337 , 文章类型： Article，,卷期：2012年130-6]
- Renal clear cell carcinoma (RCCC) is the most frequent subpopulation of renal cell carcinoma and is derived from the proximal uriniferous tubules. We have previously reported that an actin-binding protein, 4.1B/DAL-1, is...
- Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)
[作者：Ter-Minassian, M; Asomaning, K; Zhao, Y; Chen, F; Su, L; Carmella, SG; Lin, XH; Hecht, SS; Christiani, DC,期刊：International Journal of Cancer, 页码：1338-1346 , 文章类型： Article，,卷期：2012年130-6]
- Urinary metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides, termed total NNAL, have recently be...
- Increased incidence of aflatoxin B1-induced liver tumors in hepatitis virus C transgenic mice
[作者：Jeannot, E; Boorman, GA; Kosyk, O; Bradford, BU; Shymoniak, S; Tumurbaatar, B; Weinman, SA; Melnyk, SB; Tryndyak, V; Pogribny, IP; Rusyn, I,期刊：International Journal of Cancer, 页码：1347-1356 , 文章类型： Article，,卷期：2012年130-6]
- Viral hepatitis and aflatoxin B1 (AFB1) exposure are common risk factors for hepatocellular carcinoma (HCC). The incidence of HCC in individuals coexposed to hepatitis C (HCV) or B virus and AFB1 is greater than could be...
- A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors
[作者：Torti, D; Sassi, F; Galimi, F; Gastaldi, S; Perera, T; Comoglio, PM; Trusolino, L; Bertotti, A,期刊：International Journal of Cancer, 页码：1357-1366 , 文章类型： Article，,卷期：2012年130-6]
- The MET oncogene is amplified in a fraction of human gastric carcinoma cell lines, with consequent overexpression and constitutive activation of the corresponding protein product, the Met tyrosine kinase receptor. This g...
- Evaluation of predictive models in daily practice for the identification of patients with Lynch syndrome
[作者：Tresallet, C; Brouquet, A; Julie, C; Beauchet, A; Vallot, C; Menegaux, F; Mitry, E; Radvanyi, F; Malafosse, R; Rougier, P; Nordlinger, B; Laurent-Puig, P; Boileau, C; Emile, JF; Muti, C; Penna, C; Hofmann-Radvanyi, H,期刊：International Journal of Cancer, 页码：1367-1377 , 文章类型： Article，,卷期：2012年130-6]
- The optimal strategy for identifying patients with Lynch syndrome among patients with newly diagnosed colorectal cancer (CRC) is still debated. Several predictive models (e.g., MMRpredict, PREMM1,2 and MMRpro) combining ...
- Circulating micro-RNA expression profiles in early stage nonsmall cell lung cancer
[作者：Heegaard, NHH; Schetter, AJ; Welsh, JA; Yoneda, M; Bowman, ED; Harris, CC,期刊：International Journal of Cancer, 页码：1378-1386 , 文章类型： Article，,卷期：2012年130-6]
- Circulating micro-RNA (miR) profiles have been proposed as promising diagnostic and prognostic biomarkers for cancer, including lung cancer. We have developed methods to accurately and reproducibly measure micro-RNA leve...
- Reported behavior of eating anything at anytime and risk of colorectal cancer in women
[作者：Bao, Y; Nimptsch, K; Chan, AT; Ng, K; Meyerhardt, JA; Willett, WC; Giovannucci, E; Fuchs, CS,期刊：International Journal of Cancer, 页码：1395-1400 , 文章类型： Article，,卷期：2012年130-6]
- Although numerous studies have assessed the effect of foods and nutrients on colorectal carcinogenesis, few studies have investigated human eating behavior in relation to risk of colorectal cancer. In our study, we asses...
- Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status
[作者：Zaineddin, AK; Vrieling, A; Buck, K; Becker, S; Linseisen, J; Flesch-Janys, D; Kaaks, R; Chang-Claude, J,期刊：International Journal of Cancer, 页码：1401-1410 , 文章类型： Article，,卷期：2012年130-6]
- Lignans are a group of estrogenic compounds present in plants. Several epidemiological studies proposed that lignans may protect against breast cancer by exerting anticarcinogenic activity. Levels of enterolactone were d...
- Body fat distribution, weight change during adulthood, and thyroid cancer risk in the NIH-AARP Diet and Health Study
[作者：Kitahara, CM; Platz, EA; Park, Y; Hollenbeck, AR; Schatzkin, A; de Gonzalez, AB,期刊：International Journal of Cancer, 页码：1411-1419 , 文章类型： Article，,卷期：2012年130-6]
- Body mass index (BMI) has been positively associated with thyroid cancer risk in several studies, but the underlying mechanisms remain unclear. We examined the associations for waist and hip circumference and weight chan...
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