- Dickkopf1: A tumor suppressor or metastasis promoter?
[作者：Menezes, ME; Devine, DJ; Shevde, LA; Samant, RS,期刊：International Journal of Cancer, 页码：1477-1483 , 文章类型： Review，,卷期：2012年130-7]
- Dickkopf1 (DKK1), a secreted inhibitor of the Wnt/beta-catenin pathway, is a negative regulator of bone formation. DKK1 acts as a switch that transitions prostate cancer bone metastases from osteolytic to osteoblastic an...
- Dichloroacetate inhibits neuroblastoma growth by specifically acting against malignant undifferentiated cells
[作者：Vella, S; Conti, M; Tasso, R; Cancedda, R; Pagano, A,期刊：International Journal of Cancer, 页码：1484-1493 , 文章类型： Article，,卷期：2012年130-7]
- The small, water soluble molecule Dichloroacetate (DCA) is recently arousing lively interests in the field of cancer therapy for it has been shown to be able to inhibit the growth of human tumors acting specifically on t...
- Pharmacologic downregulation of c-FLIPL restores juxtacrine death receptor-mediated apoptosis in cancer cells in a peritoneal carcinomatosis model
[作者：Shen, Y; Herde, R; Doxey, BW; Xu, CX; Gray, PD; Kuwada, SK,期刊：International Journal of Cancer, 页码：1494-1503 , 文章类型： Article，,卷期：2012年130-7]
- Metastasis occurs when circulating cancer cells implant in normal secondary tissues. Paradoxically, many cancer cells express death receptors while many normal tissues express the cognate death receptor ligands, suggesti...
- In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH
[作者：Chiche, J; Le Fur, Y; Vilmen, C; Frassineti, F; Daniel, L; Halestrap, AP; Cozzone, PJ; Pouyssegur, J; Lutz, NW,期刊：International Journal of Cancer, 页码：1511-1520 , 文章类型： Article，,卷期：2012年130-7]
- We present an investigation of tumor pH regulation, designed to support a new anticancer therapy concept that we had previously proposed. Our study uses a tumor model of ras-transformed hamster fibroblasts, CCL39, xenogr...
- Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth
[作者：Wolff, DW; Xie, Y; Deng, CS; Gatalica, Z; Yang, MJ; Wang, B; Wang, JC; Lin, MF; Abel, PW; Tu, YP,期刊：International Journal of Cancer, 页码：1521-1531 , 文章类型： Article，,卷期：2012年130-7]
- G-protein-coupled receptor (GPCR)-stimulated androgen-independent activation of androgen receptor (AR) contributes to acquisition of a hormone-refractory phenotype by prostate cancer. We previously reported that regulato...
- ETV5 transcription factor is overexpressed in ovarian cancer and regulates cell adhesion in ovarian cancer cells
[作者：Llaurado, M; Abal, M; Castellvi, J; Cabrera, S; Gil-Moreno, A; Perez-Benavente, A; Colas, E; Doll, A; Dolcet, X; Matias-Guiu, X; Vazquez-Levin, M; Reventos, J; Ruiz, A,期刊：International Journal of Cancer, 页码：1532-1543 , 文章类型： Article，,卷期：2012年130-7]
- Epithelial ovarian cancer is the most lethal gynecological malignancy and the fifth leading cause of cancer deaths in women in the Western world. ETS transcription factors are known to act as positive or negative regulat...
- Analysis of the cellular uptake and nuclear delivery of insulin-like growth factor binding protein-3 in human osteosarcoma cells
[作者：Micutkova, L; Hermann, M; Offterdinger, M; Hess, MW; Matscheski, A; Pircher, H; Muck, C; Ebner, HL; Laich, A; Ferrando-May, E; Zwerschke, W; Huber, LA; Jansen-Durr, P,期刊：International Journal of Cancer, 页码：1544-1557 , 文章类型： Article，,卷期：2012年130-7]
- Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) regulates cell proliferation and survival by extracellular interaction and inactivation of the growth factor IGF-I. Beyond that, IGF-independent actions mediat...
- Candidate driver genes in microsatellite-unstable colorectal cancer
[作者：Alhopuro, P; Sammalkorpi, H; Niittymaki, I; Bistrom, M; Raitila, A; Saharinen, J; Nousiainen, K; Lehtonen, HJ; Heliovaara, E; Puhakka, J; Tuupanen, S; Sousa, S; Seruca, R; Ferreira, AM; Hofstra, RMW; Mecklin, JP; Jarvinen, H; Ristimaki, A; Orntoft, TF; Hautaniemi, S; Arango, D; Karhu, A; Aaltonen, LA,期刊：International Journal of Cancer, 页码：1558-1566 , 文章类型： Article，,卷期：2012年130-7]
- Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed in similar to 15% of all colorectal cancers (CRCs). Microsatellite mutations that drive tumourigenesis, typically inactiv...
- p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers
[作者：Bond, CE; Umapathy, A; Ramsnes, I; Greco, SA; Zhao, ZZ; Mallitt, KA; Buttenshaw, RL; Montgomery, GW; Leggett, BA; Whitehall, VLJ,期刊：International Journal of Cancer, 页码：1567-1576 , 文章类型： Article，,卷期：2012年130-7]
- The majority of serrated pathway colorectal cancers have mutation of the BRAF oncogene and display the CpG island methylator phenotype (CIMP). Half these cancers have microsatellite instability (MSI) and an excellent pro...
- Cetuximab +/- chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro
[作者：Correale, P; Botta, C; Cusi, MG; Del Vecchio, MT; De Santi, MM; Savellini, GG; Bestoso, E; Apollinari, S; Mannucci, S; Marra, M; Abbruzzese, A; Aquino, A; Turriziani, M; Bonmassar, L; Caraglia, M; Tagliaferri, P,期刊：International Journal of Cancer, 页码：1577-1589 , 文章类型： Article，,卷期：2012年130-7]
- Cetuximab is a human/mouse chimeric IgG1 monoclonal antibody (mAb) to epidermal growth factor receptor, approved for colorectal carcinoma treatment in combination with chemotherapy. The immune-mediated effects elicited b...
- Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect (TM) versus Veridex CellSearch (TM) system
[作者：Andreopoulou, E; Yang, LY; Rangel, KM; Reuben, JM; Hsu, L; Krishnamurthy, S; Valero, V; Fritsche, HA; Cristofanilli, M,期刊：International Journal of Cancer, 页码：1590-1597 , 文章类型： Article，,卷期：2012年130-7]
- The detection of CTCs prior to and during therapy is an independent and strong prognostic marker, and it is predictive of poor treatment outcome. A major challenge is that different technologies are available for isolati...
- Colon cancer associated transcript-1: A novel RNA expressed in malignant and pre-malignant human tissues
[作者：Nissan, A; Stojadinovic, A; Mitrani-Rosenbaum, S; Halle, D; Grinbaum, R; Roistacher, M; Bochem, A; Dayanc, BE; Ritter, G; Gomceli, I; Bostanci, EB; Akoglu, M; Chen, YT; Old, LJ; Gure, AO,期刊：International Journal of Cancer, 页码：1598-1606 , 文章类型： Article，,卷期：2012年130-7]
- Early detection of colorectal cancer (CRC) is currently based on fecal occult blood testing (FOBT) and colonoscopy, both which can significantly reduce CRC-related mortality. However, FOBT has low-sensitivity and specifi...
- CpG island methylation status of miRNAs in esophageal squamous cell carcinoma
[作者：Chen, XD; Hu, HM; Guan, XY; Xiong, G; Wang, Y; Wang, K; Li, J; Xu, XQ; Yang, K; Bai, Y,期刊：International Journal of Cancer, 页码：1607-1613 , 文章类型： Article，,卷期：2012年130-7]
- Previous studies on esophageal squamous cell carcinoma (ESCC) indicated that it contains much dysregulation of microRNAs (miRNAs). DNA hypermethylation in the miRNA 5' regulatory region is a mechanism that can account fo...
- Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community
[作者：Zhang, XH; Xue, LY; Xing, LX; Wang, JL; Cui, JF; Mi, JM; Xing, X; Wang, J; Du, ZJ; Misumi, J; Tian, QB; Wang, LQ,期刊：International Journal of Cancer, 页码：1614-1619 , 文章类型： Article，,卷期：2012年130-7]
- The correlation between low serum PG level and H. pylori infection with the development of gastric cancer has caused considerable concerns all over the world. Some authors exclaimed that gastric cancer developed only in ...
- Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis
[作者：Chen, X; Hu, ZB; Wang, WJ; Ba, Y; Ma, LJ; Zhang, CN; Wang, C; Ren, ZJ; Zhao, Y; Wu, SJ; Zhuang, R; Zhang, YX; Hu, H; Liu, CZ; Xu, L; Wang, J; Shen, HB; Zhang, JF; Zen, K; Zhang, CY,期刊：International Journal of Cancer, 页码：1620-1628 , 文章类型： Article，,卷期：2012年130-7]
- The detection of nonsmall cell lung cancer (NSCLC) at an early stage presents a daunting challenge due to the lack of a specific noninvasive marker. The discovery of microRNAs (miRNAs), particularly those found in serum,...
|